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male

  1. haidut

    Hypogonadism in older males due to low OXPHOS

    I suspect many readers will simply say "duh!", but believe or not the origin of age-related hypogonadism in males is still considered unknown. Most endocrinologists have discovered experimentally that treating their patients with SERM or AI drugs restores androgens to youthful levels, but the...
  2. ScurveDream

    Thoughts on THIS BOOK? "The Manipulated Man" - Female author bashes women/supports (redpilled?) men AKA battle of the sexes!

    I had never heard of this book ... Apparently it's a female author (surprising?) who elaborates on how women only are capable of making men in to their slaves AKA women rule over men. Also relevant to some previous threads here since this is about the "battle between the sexes" AKA the...
  3. haidut

    Vitamin A is required for male fertility

    I am posting about this study not because I am thrilled at the possibility of society now having oral (non-steroid) contraceptive methods for males, but rather because this study highlights that vitamin A is actually required for male fertility. Even minor interference with so-called retinoic...
  4. koreus

    Waking up early with painful morning wood

    I usually go to bed between 11pm and 12am and sleep 8 - 9 hours but lately I have been waking up at 5 or 6am with extreme morning wood. It's actually a little painful and causes me to wake up. I usually fall back asleep within 10 to 15 minutes but the remaining sleep is not restful and I need...
  5. haidut

    Dietary PUFA In Childhood Causes Diabetes And Irreversible (male) Infertility

    A great study, which corroborates the discussion in another recent post of mine on PUFA's role in infertility and insulin-resistance / diabetes. However, the study below found that the infertility caused by dietary PUFA exposure were NOT reversible upon discontinuation of the high-fat (both PUFA...
  6. haidut

    Male Sexual Function Does NOT Require Estrogen

    It is a "sacred" mantra in the medical and sports worlds - i.e. "estrogen is crucial for males, without it they won't have any sex life". This mantra is also part of the justification given for the currently ongoing COVID-19 clinical trials with males receiving estrogen in the hope it will...
  7. haidut

    Eating 1 Lb Of Sugar Daily Has Strikingly Positive Effects On (male) Fertility

    When I saw this news article pop up in my daily feed I immediately thought to myself "This study will never get covered by large mainstream news outlets". And of course, the websites of CNN, Fox, ABC, CNBC, USA Today, etc have no trace of an article covering the study or even just the basic...
  8. haidut

    Male Fertility Depends On Intensity Of (sperm) Metabolism

    Yet another aspect of health that turns out to be directly controlled by quality/speed of metabolism. I made a few posts in the past demonstrating that progesterone and pregnenolone activate a calcium channel (CatSper) specific to progesterone, which greatly increases sperm motility...
  9. haidut

    Testosterone Does NOT Impair Empathy In Men

    I am sure most readers are quite familiar with the cliche that testosterone (T) is what drives stereotypical "boy behavior" - aggressiveness, carelessness, impulsive behavior, risk taking, cheating, and of course the militaristic attitude characterized by lack of (or reduced) empathy. As I...
  10. haidut

    Fertility Depends On Metabollism (ATP), Not Age

    As many of you know, there are 2 fundamental dogmas in reproductive medicine. One is that every woman is born with a fixed number of eggs and those cannot be replenished. The second one is that there is a biological fertility clock in every woman that inexorably ticks, and if the female does not...
  11. haidut

    Androsterone May Be The Main Source Of DHT, Drives Fetal Masculinization

    The study below demonstrates that not only may androsterone be the primary pro-hormone used endogenously for DHT synthesis, it likely also drives the masculinization of sexual organs in the fetus. For a long time it was thought that the so-called "front pathway" using testosterone (T) produced...
  12. haidut

    Antidepressants (SSRI) Make Females Unattractive, Provoke Male Aggression

    ...or at least it does so in birds. The news about the pure evil that SSRI drugs are just keep on coming. There is already evidence that they pretty much zombify the person taking them and deprive that person of any semblance of humanity. SSRI Drugs Linked To At Least 28 Murders, Including Mass...
  13. haidut

    Dads Pass On More Than Genetics In Their Sperm

    Another good study showing that our lifestyle choices directly affect our future children, despite what the morons in white coats keeps repeating. It has been known for years that dads in poorer health tend to beget more sickly children but the explanation had always been genetic - i.e. the dad...
  14. haidut

    Protein Quality, Not Genes, Determine Male Height

    I posted a study on the height of Dutch men - a well studied phenomenon officially explained by genes, but recently recast as one possibly due to diet. Dutch People Gained 20cm Of Height In Just 150 Years Now this new study adds more evidence to the diet hypothesis as it found a population in...
  15. haidut

    Androsterone - Androgenic Neurosteroid Required For Male Sexual Behavior

    I recently posted a study about DHT being required for male sexual behavior and orgasm. That study did not look specifically into whether DHT or one of its downstream metabolites was indeed responsible for male sexual function. This study went a bit further and claims that it is androsterone...
  16. haidut

    Infertility In Men Linked To High Estrogen

    Not really surprising but some "studied" have tried to paint a link between increased androgens and infertility, so I thought this would be good post here as a counter-perspective. Increased oestradiol level in seminal plasma in infertile men. - PubMed - NCBI "...Seminal hormonal patterns in...
  17. natedawggh

    Progesterone Use For Males

    From February to March of this year I noticed a decrease in the quality of my appearance, as if I were re-aging again. I thought I would go on Progesterone once more. I used it before, with great benefits but some seeming unwanted effects (or so I thought)... Just two days of natural...
  18. haidut

    Male Fertility Requires Progesterone And Antagonism Of A PUFA Metabolite

    Ray has written many times on progesterone's role in both female and male health. This study discovered that sperm actually has a progesterone "receptor" on its tail, and it is the activation of this "receptor" by progesterone that allows sperm to make the final push into the egg and perform the...
  19. EndAllDisease

    Progesterone Daily For Men?

    Hey I bought some Progest-E to experiment with it for it's anti-stress effects. I am currently taking pregnenolone, EstroBan, DHEA, Aspirin, Niacinamide, and Methylene Blue daily, and have purchased Progest-E to add to the mix. I understand that Progesterone is anti-Androgenic so I'm a bit...
  20. L

    Progest E [Can Anyone Help Me Taper Off?]

    I have been doing about 5 days of progest E as per the instructions, and some thyroid(called thytrophin), and it seems to be having some side effect. When I get the bee sting sensation, I try and take another dose earlier and/or some aspirin. So should I just keep plowing through? I know some...
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