lsd

https://www.nature.com/articles/d41586-021-00187-9

A few days ago I did a post on 2-bromo-LSD as a better LSD alternative . 2-bromo-lsd ,lacks the hallucinogenic effect of LSD ,which might be due to a stronger anti-serotonin effect . The problem is: it is very hard to get and pretty expensive, plus its illegal . Today I stumbled...

Neurotherapeutics. 2020 Nov 12. doi: 10.1007/s13311-020-00962-y. Online ahead of print. Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin Emmanuelle A D Schindler, R Andrew Sewell, Christopher H Gottschalk, Christina Luddy, L Taylor Flynn, Hayley Lindsey, Brian P...

For the last 5+ decades, Big Pharma and public health officials together with the entire law enforcement apparatus have been propagating myths, lies and outright fraud in regards to psychedelic drugs and especially about LSD. This attitude grew out of the civil rights movement and protests in...

I come across study after study of Psilocybin, DMT, LSD being used to reset the brains of Depressed people, and help alcoholics, etc. I can obtain Mushrooms, LSD, and 5MEODMT, and want to use these in small amounts to see if they can help. How exactly are they purported to reset the brain though...

Peat wrote a few times on the brain's innate need to dream and how anti-serotonin chemicals like LSD removes the barriers on consciousness imposed by an authoritarian culture. He said that the ability to dream in an awake state is an indication of high metabolic rate and that is a testament to...

This is something that's been bugging me about Ray's work for a little while. He claims that LSD is "approximately" a serotonin receptor antagonist. To start with, the claim seems very broad, given how many different subtypes of serotonin receptors there are. And its a claim that he doesn't...

Ray wrote about the usage of drugs like bromocriptine as an actual cure for certain types of cancer. He did not specify which cancers but given the causative role of prolactin in both breast and prostate cancer, I'd suspect these two were on his list. These studies below show that prolactin...

I have written before about the well-known tendency of people with depression, PTSD, and other traumatic disorders to ruminate and focus intensively on analyzing past events. This is one of the reason people with such conditions tend to abuse alcohol. In addition to temporarily lowering stress...

http://www.ncbi.nlm.nih.gov/pubmed/5492893

There is one thing I don't understand about LSD. From what I have Read from Ray Peat LSD is named antiserotonergic substance. But in other places like Wikipedia or medical articles on pubmed there is info that LSD psychodelic properties comes mainly from 5-HT2 agonism, not antagonizm. 5-HT2a...

I’ve decided that I want to share my LSD experience, at least as it pertains to how it affected my body. I’ve tried small doses of LSD in the past, ranging from about 10mcg to 60mcg. At 10mcg I first noticed an increase in anxiety and panic-sweating which then gave way to a cooling down of...