1. haidut

    Serotonin (5-HT) causes anxiety, LSD and its derivatives may be treat it

    The so-called generalized anxiety disorder (GAD) is perhaps the most commonly diagnosed mental health condition. Ergo, the drugs to treat GAD - the benzodiazepine (GABA agonist) class - are perhaps the most widely prescribed mental health drugs globally. Unfortunately, chronic use of such drugs...
  2. P

    Cypro made me hallucinate

    So i've been taking cypro past the last 5 days. I was tooking 2mg on lunch and 2mg on dinner. It was being amazingly therapeutic for me (i was happier, seeing colors more vibrant, enjoying more life, recovering from the learned helplessness i was stuck in, etc). Today i decided to take 2mg on...
  3. haidut

    Dopaminergic/antiserotonin drug treats schizophrenia - psychiatry is a giant FRAUD!

    Some people make take issue with the title and claim that it is too dramatic. In this case, at least, the title may even be an understatement in regards to evidence of just how utterly FRAUDULENT psychiatry is and has been for decades. Speaking of the latter, psychiatry has claimed for decades...
  4. NewACC

    Study says: Cyproheptadine is Serotonin Antagonist, Doesn't Block Dopamine and Noradrenaline Abstract "...Cyproheptadine and LSD, two known antagonists of the peripheral effects of 5-HT, were administered i.v. to conscious rabbits at different times before the intracerebroventricular (i.c.v.) administration of 5-HT, NAD or dopamine...
  5. NewACC

    Serotonin antagonists fail to prevent endotoxin lethality in healthy mice Very scary article. I'd be glad if @haidut and @Hans commented it
  6. haidut

    Serotonin enhances learning from punishment, reduces learning from reward

    Research as early as the 1960s firmly established that there is nothing "happy" when it comes to serotonin (5-HT). Namely, elevated 5-HT levels were found in many chronic diseases and especially clinical depression. It took more than 7 decades for medicine to finally start admitting that 5-HT is...
  7. 'peataphysique

    American Pravda: Waging Biological Warfare
  8. Mauritio

    Psychedelic effect of psilocybin/ LSD mediated through 5ht2a + psychedelics increase neuroplasticity!

    This is study underlines what peat has stated before ,namely that the hallucinations of psychedelics are mediated through serotonin. To be precise it's the 5-HT2a receptor that does that. And the intensity of the experience actually correlated with 5ht2a receptor occupancy. "We report for the...
  9. R How ecstasy and psilocybin are shaking up psychiatry
  10. Mauritio

    1-acetyl- LSD, a better LSD-alternative? (aka ALD-52)

    A few days ago I did a post on 2-bromo-LSD as a better LSD alternative . 2-bromo-lsd ,lacks the hallucinogenic effect of LSD ,which might be due to a stronger anti-serotonin effect . The problem is: it is very hard to get and pretty expensive, plus its illegal . Today I stumbled...
  11. A

    Exploratory Controlled Study Of The Migraine-Suppressing Effects Of Psilocybin

    Neurotherapeutics. 2020 Nov 12. doi: 10.1007/s13311-020-00962-y. Online ahead of print. Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin Emmanuelle A D Schindler, R Andrew Sewell, Christopher H Gottschalk, Christina Luddy, L Taylor Flynn, Hayley Lindsey, Brian P...
  12. haidut

    LSD Enters Clinical Trials For Alzheimer Disease (AD)

    For the last 5+ decades, Big Pharma and public health officials together with the entire law enforcement apparatus have been propagating myths, lies and outright fraud in regards to psychedelic drugs and especially about LSD. This attitude grew out of the civil rights movement and protests in...
  13. Frankdee20

    Using Psychedelics To "Reset The Brain"

    I come across study after study of Psilocybin, DMT, LSD being used to reset the brains of Depressed people, and help alcoholics, etc. I can obtain Mushrooms, LSD, and 5MEODMT, and want to use these in small amounts to see if they can help. How exactly are they purported to reset the brain though...
  14. haidut

    Babies Experience Life As An LSD Trip, As A Result Of Their High Metabolism

    Peat wrote a few times on the brain's innate need to dream and how anti-serotonin chemicals like LSD removes the barriers on consciousness imposed by an authoritarian culture. He said that the ability to dream in an awake state is an indication of high metabolic rate and that is a testament to...
  15. energyandstruct

    Is Peat Wrong About LSD? Or Just Too Vague? Antagonism Vs Agonism

    This is something that's been bugging me about Ray's work for a little while. He claims that LSD is "approximately" a serotonin receptor antagonist. To start with, the claim seems very broad, given how many different subtypes of serotonin receptors there are. And its a claim that he doesn't...
  16. haidut

    LSD-derivatives Like Bromocriptine Can Fully Cure Breast Cancer

    Ray wrote about the usage of drugs like bromocriptine as an actual cure for certain types of cancer. He did not specify which cancers but given the causative role of prolactin in both breast and prostate cancer, I'd suspect these two were on his list. These studies below show that prolactin...
  17. haidut

    LSD Forces People To Think About The Present/future And Not The Past

    I have written before about the well-known tendency of people with depression, PTSD, and other traumatic disorders to ruminate and focus intensively on analyzing past events. This is one of the reason people with such conditions tend to abuse alcohol. In addition to temporarily lowering stress...
  18. michael94

    Lsd: Antagonizes Serotonin And Glutamate Excitation
  19. M

    Question About LSD

    There is one thing I don't understand about LSD. From what I have Read from Ray Peat LSD is named antiserotonergic substance. But in other places like Wikipedia or medical articles on pubmed there is info that LSD psychodelic properties comes mainly from 5-HT2 agonism, not antagonizm. 5-HT2a...
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