1. 'peataphysique

    American Pravda: Waging Biological Warfare
  2. Mauritio

    Psychedelic effect of psilocybin/ LSD mediated through 5ht2a + psychedelics increase neuroplasticity!

    This is study underlines what peat has stated before ,namely that the hallucinations of psychedelics are mediated through serotonin. To be precise it's the 5-HT2a receptor that does that. And the intensity of the experience actually correlated with 5ht2a receptor occupancy. "We report for the...
  3. R How ecstasy and psilocybin are shaking up psychiatry
  4. Mauritio

    1-acetyl- LSD, a better LSD-alternative? (aka ALD-52)

    A few days ago I did a post on 2-bromo-LSD as a better LSD alternative . 2-bromo-lsd ,lacks the hallucinogenic effect of LSD ,which might be due to a stronger anti-serotonin effect . The problem is: it is very hard to get and pretty expensive, plus its illegal . Today I stumbled...
  5. A

    Exploratory Controlled Study Of The Migraine-Suppressing Effects Of Psilocybin

    Neurotherapeutics. 2020 Nov 12. doi: 10.1007/s13311-020-00962-y. Online ahead of print. Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin Emmanuelle A D Schindler, R Andrew Sewell, Christopher H Gottschalk, Christina Luddy, L Taylor Flynn, Hayley Lindsey, Brian P...
  6. haidut

    LSD Enters Clinical Trials For Alzheimer Disease (AD)

    For the last 5+ decades, Big Pharma and public health officials together with the entire law enforcement apparatus have been propagating myths, lies and outright fraud in regards to psychedelic drugs and especially about LSD. This attitude grew out of the civil rights movement and protests in...
  7. Frankdee20

    Using Psychedelics To "Reset The Brain"

    I come across study after study of Psilocybin, DMT, LSD being used to reset the brains of Depressed people, and help alcoholics, etc. I can obtain Mushrooms, LSD, and 5MEODMT, and want to use these in small amounts to see if they can help. How exactly are they purported to reset the brain though...
  8. haidut

    Babies Experience Life As An LSD Trip, As A Result Of Their High Metabolism

    Peat wrote a few times on the brain's innate need to dream and how anti-serotonin chemicals like LSD removes the barriers on consciousness imposed by an authoritarian culture. He said that the ability to dream in an awake state is an indication of high metabolic rate and that is a testament to...
  9. debored13

    Is Peat Wrong About LSD? Or Just Too Vague? Antagonism Vs Agonism

    This is something that's been bugging me about Ray's work for a little while. He claims that LSD is "approximately" a serotonin receptor antagonist. To start with, the claim seems very broad, given how many different subtypes of serotonin receptors there are. And its a claim that he doesn't...
  10. haidut

    LSD-derivatives Like Bromocriptine Can Fully Cure Breast Cancer

    Ray wrote about the usage of drugs like bromocriptine as an actual cure for certain types of cancer. He did not specify which cancers but given the causative role of prolactin in both breast and prostate cancer, I'd suspect these two were on his list. These studies below show that prolactin...
  11. haidut

    LSD Forces People To Think About The Present/future And Not The Past

    I have written before about the well-known tendency of people with depression, PTSD, and other traumatic disorders to ruminate and focus intensively on analyzing past events. This is one of the reason people with such conditions tend to abuse alcohol. In addition to temporarily lowering stress...
  12. michael94

    Lsd: Antagonizes Serotonin And Glutamate Excitation
  13. M

    Question About LSD

    There is one thing I don't understand about LSD. From what I have Read from Ray Peat LSD is named antiserotonergic substance. But in other places like Wikipedia or medical articles on pubmed there is info that LSD psychodelic properties comes mainly from 5-HT2 agonism, not antagonizm. 5-HT2a...
  14. S

    My LSD Experience

    I’ve decided that I want to share my LSD experience, at least as it pertains to how it affected my body. I’ve tried small doses of LSD in the past, ranging from about 10mcg to 60mcg. At 10mcg I first noticed an increase in anxiety and panic-sweating which then gave way to a cooling down of...