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An epidemiological study, yet still useful IMO since the correlation was maintained across the various levels of PUFA intake - i.e. the higher the PUFA intake the higher the prevalence of a mental disorder such as depression, which suggests a causal link. The link was the strongest in males and...
The rates of MS have been steadily rising over the last several decades. While mainstream medicine claims the cause is "unknown", it is well known that it has an almost perfect inverse association with sunshine exposure, vitamin D levels, aspirin usage, histamine blockers, etc. This suggest an...
The study below demonstrates yet again that there is hardly an aspect of human health that PUFA does not influence in a detrimental manner, even seemingly non-metabolic aspects such as bacterial infections. As it turns out, most bacteria express the enzyme family known as lipoxygenases (LOX) and...
Over the years I have posted a number of studies on the roles of PUFA metabolites such as prostaglandins and leukotrienes in many chronic conditions including cancer, Alzheimer, Parkinson, ALS, MS, CVD, etc. For those that are new to this issue, COX enzymes are responsible for prostaglandin...
These studies show that PUFA has both direct (linoleic) and secondary (through LOX) stimulating effect on prostate cancer growth, independently of any hormones. Inhibiting the LOX-5 pathway led to immediate growth arrest and apoptosis of prostate cancer cells.
The important message for both...
I posted a few studied showing PUFA and its metabolites are strongly involved in AD and brain aging in general.
Increased Pufa Oxidation May Be Biomarker For Alzheimers
Blocking Inflammation From PUFA Reverses Brain Aging
The second link above discussed specifically the inhibition of the...