longevity

  1. Peatful

    Living to 120. Pregnancies at 65. See what they eat and how they live.

    View: https://youtu.be/QW_713n3D0o Fascinating.
    • Peatful
    • Thread
    • cheese community environment fruit health longevity vitamin d
    • Replies: 32
    • Forum: Health
  2. B

    NIH Longevity Testing Program - Interventions that extend lifespan in mice

    Came across the NIH Interventions Testing Program. Pretty interesting info. Interventions Testing Program (ITP) Interventions shown to extend lifespan in UM-HET3 mice include; Aspirin – Increased lifespan in males but not females (Strong et al., 2008). Rapamycin – Increased mean and...
  3. A

    Hypercapnia-inducible factor: a hypothesis | Aging and longevity

    Abstract Cells and tissues sense and respond to hypercapnia by global activation or down-regulation of hundreds of genes and switching on/off a number of signaling and metabolic pathways. We hypothesize for the first time that such complex rearrangements are hardly possible without subtle...
  4. A

    Aspirin was the most potent life-extension agent when data for all model organisms was combined, more so than rapamycin or metformin

    Research on aging and lifespan-extending compounds has been carried out using diverse model organisms, including yeast, worms, flies and mice. Many studies reported the identification of novel lifespan‐extending compounds in different species, some of which may have the potential to translate to...
  5. Apple

    World's oldest person - Kane Tanaka (118yo)

    Just stumbled on this peaty centenarian - Kane Tanaka. She likes eating chocolate and drinking Coke. Secret to her longevity, Tanaka replied, “Eating delicious food and studying.”...
    • Apple
    • Thread
    • centenarians coca cola coke diet longevity
    • Replies: 8
    • Forum: Breaking News
  6. haidut

    Metabolically, children are different species compared to adults

    A great study, which once again puts metabolism in the spotlight. Many studies have tried to discover the main biological differences between children and adults and so far none of them have discovered a "smoking gun". At the same time, multiple studies have demonstrated that children are much...
    • haidut
    • Thread
    • babies children evolution health kids longevity metabolic rate metabolism
    • Replies: 18
    • Forum: Scientific Studies
  7. haidut

    Inflammation (from PUFA), not telomeres, determines lifespan / healthspan

    The idea of lifespan being entirely determined by limits on cellular division has ruled biology for more than a century and is perhaps best exemplified by the (in)famous (and false) Hayflick limit. Reaching the said limit is postulated to be controlled by telomere length, and as such the...
    • haidut
    • Thread
    • aging aspirin centenarian inflammation lifespan longevity pufa telomere
    • Replies: 0
    • Forum: Scientific Studies
  8. Mauritio

    Why PUFA is bad: how high membrane polyunsaturation decreases longevity

    Why PUFA is bad: how high membrane polyunsaturation decreases longevity: This is probably one of the most interesting papers I've read in a long time . It goes into depth about the danger of PUFA and conncects the dots between PUFA ,membranes ,rate of living theory, life expectancy, and...
    • Mauritio
    • Thread
    • free radicals longevity membranes mufa pufa rate of living sfa
    • Replies: 72
    • Forum: Scientific Studies
  9. youngsinatra

    Rate My Anti-Aging Stack

    Hello everyone, I am personally very interested in longevity and extending healthy lifespan. I am curious if some of you are also into this field of interest and could give me some advice for what you would change/add/remove. My supplement stack: 1. Fat-solubles: (All dissolved in MCT-oil...
  10. P

    55 year-old looks like 25

    Interesting video about a 55 year-old photographer who looks like an elite 25 year-old fitness model. He's 55 Years Old But Looks 25... Reacting To Chuando Tan Reveal His Secrets Summary: He looks the same as he did in the late 1980s, in his 20s. He doesn't drink or smoke, doesn't drink coffee...
  11. M

    Metabolic Rate & Longevity

    Peat's central premise is that a high metabolic rate will improve chances of longevity. This is in direct contrast to the mainstream premise. (Just look up "metabolic rate longevity") to get an idea of this. I'm trying to gather up evidence for the idea that a higher metabolic rate gives us a...
    • metabolizm
    • Thread
    • longevity metabolic rate
    • Replies: 2
    • Forum: Metabolism
  12. haidut

    Sexual activity and stress levels (HPA activity) may determine longevity

    The study below tried to tease out the main factors affecting the longevity of the legendary naked mole rat - the animal with longest lifespan in its genus, and the sole mammal known to be virtually immune to developing cancer. Most of the biological/biochemical findings in regards to naked mole...
    • haidut
    • Thread
    • dhea hpa lifespan longevity reproduction sexuality stress
    • Replies: 12
    • Forum: Scientific Studies
  13. Hans

    The Most Important Organ For Longevity

    Where is the hub in the body where all things are most likely to go wrong? The most important organ for longevity » MENELITE
  14. B

    Crickets Fed Low Dose Aspirin Live 143% Longer, Have Longer Childhoods And Higher Metabolic Rates

    We examined the impacts of aspirin and metformin on the life history of the cricket Acheta domesticus (growth rate, maturation time, mature body size, survivorship, and maximal longevity). Both drugs significantly increased survivorship and maximal life span. Maximal longevity was 136 days for...
  15. A

    Calcium Alpha-ketoglutarate. A Calcium Supplement With Added Benefits?

    While searching for the ideal calcium supplement I came across calcium alpha-ketoglutarate which I think has not been discussed on this forum yet and looks highly interesting. There is a study showing that calcium alpha-ketoglutarate extends lifespan and compresses morbidity in aging mice...
    • agnostic
    • Thread
    • ammonia calcium hyperparathyroidism longevity
    • Replies: 53
    • Forum: Calcium
  16. S

    Diet Of Japanese Longevity Expert Who Lived To 105

    This Japanese longevity expert lived to 105 — here's what he ate every day
  17. haidut

    A High-carb Diet May Explain Why Okinawans Live So Long

    Most people have heard of the so-called Okinawan "miracle" - i.e. the high ratio of centenarians per capita on that Japanese island. While that ratio is artificially elevated due to increased emigration after WWII, there is solid evidence that Okinawans have better systemic health than the rest...
    • haidut
    • Thread
    • centenarian diet health healthspan high-carb lifespan longevity low-fat low-protein okinawa okinawan
    • Replies: 148
    • Forum: Scientific Studies
  18. haidut

    Low-protein High-carb Diet Has The Same Benefits As Caloric Restriction

    A recent study posted on the forum claimed that low carb is better for weight loss than other diets. Low Carb More Effective In Weight Loss Than High Carb? But the key question which so far most dieting studies ignore is this. Is the diet actually improving health and increasing lifespan...
    • haidut
    • Thread
    • benefit caloric restriction casein diet endotoxin fasting health high-carb lifespan longevity low-protein sucrose
    • Replies: 92
    • Forum: Scientific Studies
  19. haidut

    Longevity Is NOT In Your Genes, It's In Your Choices Of Lifestyle And People

    Yet another big hit against the genetic explanation. Not only is longevity not due to genes but it can also be largely controlled by whom you associate with. Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating The Key to a Long Life Has Little...
    • haidut
    • Thread
    • assortative mating choices dna family genome lifespan lifestyle longevity social interaction
    • Replies: 16
    • Forum: Scientific Studies
  20. L

    Deprenyl – Peatarian-Safe?

    Has anyone asked Ray Peat his opinion about this drug? Would he think it is safe for long term usage? Do you think it is safe, and good to use as a nootropic?
    • Logan-
    • Thread
    • anti-aging brain deprenyl dopamine dopaminergic longevity mao-b nootropic selegiline
    • Replies: 33
    • Forum: Pharmaceutical Drugs
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