liver health

  1. Mauritio

    PUFA causes liver steatosis, Vitamin E can prevent it

    In this study they looked at the effect of PUFA on liver health and Vitamin E's capibility to prevent liver damage. They fed mice a diet high in linoleic acid, low in linoleic acid or high in linoleic acid and supplemented with Vitamin E. The results are remarkable: in many ways the Vitamin E...
  2. Mauritio

    Activating FXR decreases PUFA in the liver

    Very interesting study showing that activating the Farnesoid X Receptor results in lower levels of MUFA and PUFA in the liver. (Farnesoid X receptor - Wikipedia) Lowers levels of MUFA are brought on by downregulating genes like SCD1. "Elevated expression levels of SCD1 is found to be...
    • Mauritio
    • Thread
    • fatty liver fxr liver health mufa nafld nash pufa
    • Replies: 12
    • Forum: Fats
  3. Mauritio

    Doxycycline for liver health

    Doxycycline is beeing increasingly studied for its anti-inflammatory effects at sub-antimicrobial doses. This study shows how and that it might be helpful in avoiding liver scarring/fibrosis. It shows that MMP-8, which is released in response to LPS, activates the hepatic stellate cells...
  4. Mauritio

    Vitamin K can regenerate the liver

    I've been trying to find evidence for the mechanism of action of all vitamin K forms on regenerating/helping the liver. The MoAs mentioned on this forum are kind of vague in my opinion. I do think vitamin K can be very helpful for the liver in many ways and I think the specific MoA deserves...
    • Mauritio
    • Thread
    • liver liver health pxr quinone sxr vitamin k vitamin k2
    • Replies: 31
    • Forum: Vitamins
  5. J

    Severe Sleeplessness

    Hello, I am experiencing extreme sleeplessness and looking for insight and things to try. On the worse nights I fall asleep for about an hour or even less and then I’m awake the rest of the night. I’ve been struggling with pretty severe insomnia for the past couple of years and it’s just been...
    • Jesilyn
    • Thread
    • chronic fatigue cirs endotoxemia endotoxin insomnia liver liver health lyme sleeplessness
    • Replies: 185
    • Forum: Ask For Help or Advice
  6. Mauritio

    The Policosanols Thread

    In his latest interview with danny roddy and @haidut ray peat talked about policosanols beeing best at replacing stores PUFA over time. They start talking about it at about 1:33:00 Now this is an important topic ,yet I haven't found much info on it. Why dont we compile some info here and...
    • Mauritio
    • Thread
    • haidut liver health long chain fatty acids octacosanol policosanol policosanols pufa ray peat replacing pufa
    • Replies: 442
    • Forum: Articles & Scientific Studies
  7. michael94

    TUDCA

    decreases rates of lipid peroxidation http://www.ncbi.nlm.nih.gov/pubmed/9655521 interesting mice study demonstrating some coool effects http://www.ncbi.nlm.nih.gov/pubmed/26681941 neuroprotective too http://www.ncbi.nlm.nih.gov/pubmed/26379056 May be something worth trying if you...
    • michael94
    • Thread
    • liver liver health supplemental tudca
    • Replies: 103
    • Forum: Supplements
  8. Y

    RP Says Glucose Helps T4 To T3, Then Why Fructose?

    I am reading this statement below i got from a site: Did you know that your liver stores sugar (called glycogen), and that you NEED a steady flow of sugar to keep glycogen stores topped off? Without a healthy storage of glycogen, your liver won’t convert thyroid hormone T4 (inactive) to T3...
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