liver disease

  1. EnergeticLeo

    Feeding PUFA muffins caused less liver fat gain than SFA muffins??

    https://diabetesjournals.org/diabetes/article/63/7/2356/34338/Overfeeding-Polyunsaturated-and-Saturated-Fat I'd be very interested in others' views on this study; the only key variable changed was PUFA (sunflower oil) vs SFA (palm oil) used in muffins fed to the subjects, and the PUFA group had...
  2. xeliex

    Ascites and cirrhosis... any hope?

    My aunt is suffering from ascites and cirrhosis. She is not a drinker nor has hepatitis, but the suspected cause of sudden ascites and cirrhosis is long term (undiagnosed) fatty liver and possibly a blood clot from COVID-19. She is needing frequent paracentesis and is on lactulose. Without...
  3. haidut

    Endotoxin (LPS) as a cause of liver disease, obesity and diabetes

    The first article below is actually about praising fermented foods, which I don't really agree with. So, I am posting it mostly because of the quote on endotoxin/LPS, which is a very rare finding in published medical literature since medicine does not recognize chronic, low-grade endotoxemia as...
    • haidut
    • Thread
    • diabetes endotoxin hdl hepatitis liver disease lps obesity tlr4
    • Replies: 17
    • Forum: Scientific Studies
  4. koreus

    Just Got My Liver Enzymes Checked And They Are Elevated

    My Alanine transferase is way out of range which is worrying: Alanine transferase 220 IU/L (range 50 - 150) Gamma-GT 45 IU/L (range 34-335) Albumin 44 g/L (range 34 - 52) Alkaline phosphatase 81 IU/L (range 0 - 130) Globulin 30 g/L (range 19 - 35) Bilirubin 9 umol/L (range 0 - 40) Total...
  5. haidut

    Vitamin E Lowers Mortality, Transplantation Need In Liver Disease Patients

    Good study on the protective effects of vitamin E on progression of the liver disease known as NASH, which usually leads to cirrhosis and eventually a need for liver transplant. It is nice to see Big Pharma opening up to treatment with vitamins, but it is probably due to the failure of their...
    • haidut
    • Thread
    • cirrhosis fatty liver liver disease lower mortality nash reduce tocopherol transplantation vitamin e
    • Replies: 1
    • Forum: Scientific Studies
  6. haidut

    Niacinamide Can Treat Alcoholic Liver Disease

    As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...
    • haidut
    • Thread
    • alcohol alcoholism cirrhosis liver liver disease liver steatosis nad nad/nadh niacinamide nicotinamide riboside nr prevent redox
    • Replies: 3
    • Forum: Scientific Studies
  7. haidut

    Liver Disease Is Caused By Low ATP Driven By Fat (PUFA) Oxidation

    I posted a study several months ago on the ability of inosine to prevent/reverse liver disease, and how liver damage caused by various toxins was due to lower ATP levels in the liver. Inosine, being both a metabolite and precursor of ATP, is able to restore ATP levels and as such to...
    • haidut
    • Thread
    • atp cardiolipin cirrhosis fao fas fatty acid oxidation fatty acid synthesis liver liver disease mitochondrial dysfunction nafld nash peroxidation pufa
    • Replies: 26
    • Forum: Scientific Studies
  8. haidut

    Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked

    This is one of the unique studies that breaks away from the mainstream dogma that serotonin is the "happy hormone" and increasing it with drugs like SSRI can lead to nothing but goodness. The study not only directly states that past/current SSRI use is a risk for developing diabetes but show how...
    • haidut
    • Thread
    • 5-ht 5-ht3 5-htt diabetes endotoxemia endotoxin inflammation liver disease lps obesity pufa serotonin serotonin transporter sert tlr4
    • Replies: 45
    • Forum: Scientific Studies
  9. haidut

    Inosine Increases ATP And Reverses NAFLD (and Likely Other Liver Disease)

    As I mentioned in another recent thread on inosine and serotonin/cortisol, many pathologies are simply signs/symptoms of inefficient ATP synthesis and restoring proper synthesis or replenishing ATP levels through precursors often reverses the pathology. These two studies below show that fatty...
    • haidut
    • Thread
    • atp fatty liver inosine liver disease nafld protein synthesis purine purine salvage pathway purine synthesis
    • Replies: 39
    • Forum: Scientific Studies
  10. haidut

    Androgen Deficiency As The Main Cause Of Chronic Disease In Males

    This is one of the most comprehensive reviews that I have ever come across on the topic of androgens and their role in male health. It is authored by one of the most renowned experts in urology - the former director of the Department of Urology at Boston University (BU) School of Medicine. Given...
    • haidut
    • Thread
    • aging androgen deficiency androgen deprivation cvd dht diabetes dutasteride finasteride heart attack heart disease hepatocellular carcinoma insulin resistance liver cancer liver disease males mitochondrial dysfunction nafld sexual dysfunction stroke testosterone
    • Replies: 108
    • Forum: Scientific Studies
  11. haidut

    Alcohol Mostly Benign For The Liver, Causing Injury Requires Endotoxin (LPS)

    Peat wrote in one of his articles that alcohol is getting a bad reputation for causing all sorts of liver disease and even liver cancer, but alcohol by itself is fairly neutral for the liver and that the role of PUFA, iron and endotoxin is being neglected by mainstream medicine. The study below...
    • haidut
    • Thread
    • alcohol endotoxin ethanol fatty liver fibrosis inflammation liver disease lps nafld
    • Replies: 52
    • Forum: Scientific Studies
  12. P

    Betaine Lowers FFA And Improve Insulin Sensitivity And Adiponectine Level In High Fat Fed Animal

    Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease Endoplasmic reticulum (ER) stress plays a critical role in adipose tissue dysfunction and insulin resistance in a variety of experimental...
    • paymanz
    • Thread
    • adiponectin betaine choline diabetes fibrosis free fatty acids insulin resistance insulin sensitivity jnk leptin liver disease liver steatosis resistin
    • Replies: 7
    • Forum: Articles & Scientific Studies
  13. haidut

    Candida Overgrowth Is A Major Factor In (alcoholic) Liver Damage / Cirrhosis

    Over the last 5 years or so it has become very fashionable among many "naturopaths" to throw the diagnosis "Candida overgrowth" at every symptom of gut dysfunction people present with at the doctor. Peat has spoken about Candida overgrowth and how the fungus typically only becomes an issue in...
    • haidut
    • Thread
    • alcohol candida cirrhosis endotoxin glucans inflammation intestinal permeability liver disease lps tlr4
    • Replies: 42
    • Forum: Scientific Studies
  14. R

    Unsaturated Fats Role In Non-alcoholic Fatty Liver Disease

    At 2 minutes and 3 seconds
    • ReSTART
    • Thread
    • efa deficiency liver disease nafld pufa
    • Replies: 5
    • Forum: Fats
  15. haidut

    Vitamin D May Be Therapeutic Against Liver Fibrosis And Liver Cancer

    I posted a few threads on vitamin D and how it may help treat endotoxin-related condition, especially ones affecting the liver. Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked Conditions Endotoxin is perhaps the primary driver of actual liver fibrosis, which (if left...
    • haidut
    • Thread
    • calcitriol cancer cholecalciferol fibrosis liver disease retinol reverse treatment vitamin d
    • Replies: 0
    • Forum: Cancer
  16. haidut

    Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked Conditions

    The activation of TLR by various substances like endotoxin, ethanol / alcohol, opioids, SSRI, etc is involved in the pathogenesis of many conditions, especially IBD, colon cancer, periodontal disease, etc. There are very few effective endotoxin antagonists in clinical use, which is unfortunate...
    • haidut
    • Thread
    • antagonist calcitriol cancer cholecalciferol endotoxin fibrosis inflammation liver disease lps periodontal disease periodontitis tlr4 tnf vitamin d
    • Replies: 27
    • Forum: Scientific Studies
  17. P

    Creatine Supplementation As A Possible New Therapeutic Approach For Fatty Liver Disease

    Creatine supplementation as a possible new therapeutic approach for fatty liver disease: early findings. - PubMed - NCBI Over the last few years, consistent data have demonstrated that creatine (Cr) supplementation prevents the accumulation of fat in rat liver as well as the progression of...
  18. L

    Coffee Reverses Liver Disease

    Science Finds Drinking Coffee Can Reduce The Damage From This Bad Habit @haidut another one about coffee...
    • lollipop
    • Thread
    • article coffee liver disease
    • Replies: 26
    • Forum: Coffee
  19. haidut

    Zinc Reduces Ammonia

    Several human studies and some animals ones. Keep in mind that most of the human patients had severe liver disease and as such their ammonia levels were quite high (some people were in coma). As such, the high doses of zinc used in those studies (150mg-200mg elemental zinc per day) are probably...
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