lipolysis

  1. Juri

    THE GREAT PUFA DETOX/DEPLETION MEGA THREAD - SIMPLIFIED

    Sorry for the all caps title, I want to attract attention with it, simply because i'm counting on your guys' and girls' experiences to be shared here also. For anyone not that familiar with why one would want to lose PUFA, here is a quick summary by haidut. That being said, I made this thread...
  2. haidut

    Aspirin reduces risk of developing diabetes

    Not sure if my readers have noticed it, but Big Pharma has drastically increased their bashing of aspirin since the pandemic started. Those attacks began when a few studies published back in 2020 demonstrated that aspirin users had a much lower risk of both contracting and dying from COVID-19...
    • haidut
    • Thread
    • aspirin diabetes fatty acid oxidation inflammation lipolysis metabolism obesity
    • Replies: 12
    • Forum: Scientific Studies
  3. haidut

    PUFA metabolite (prostaglandin) promotes lipolysis / fibrosis, causes obesity / diabetes

    Just in case there are still doubts out there about just how detrimental PUFA is to our health, here is a study showing that just one of PUFA's "normal" metabolites (i.e. enzymatically derived, instead of through peroxidation) is sufficient to elevate lipolysis, and that effect alone is enough...
    • haidut
    • Thread
    • aspirin cox diabetes fibrosis lipolysis obesity pge2 prostaglandin pufa
    • Replies: 2
    • Forum: Scientific Studies
  4. haidut

    Exhaustive eccentric exercise (EEE), such as running, causes hyperlipidemia and liver damage

    ...and vitamin D can apparently reverse those negative effects, when given at a dose of just 2,000 IU daily during the exercise time period. In addition, the vitamin D supplementation resulted in a significantly bigger weight (fat) loss than the group doing only exercise. I think the biggest...
    • haidut
    • Thread
    • eccentric endurance exercise exhaustive hyperlipidemia lipolysis liver damage running
    • Replies: 12
    • Forum: Scientific Studies
  5. haidut

    A single, low dose niacinamide drops triglycerides by 75%

    Among the vitamin B3 analogs, niacin is perhaps the most famous for its ability to both raise "good" cholesterol (HDL) and also lower triglycerides. However, niacinamide, nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are all effective precursors to NAD (as niacin is) and...
    • haidut
    • Thread
    • lipolysis nad niacinamide nicotinamide nmn triglycerides vitamin b3
    • Replies: 17
    • Forum: Scientific Studies
  6. haidut

    Lipolysis preferentially releases PUFA from adipose tissue

    ...compared to SFA and/or MUFA. This topic is considered highly controversial in Peat-land, mostly because of the dearth of studies dealing with it. I must have received hundreds of emails at this point criticizing Peat's stance on this issue and claiming that there is no evidence for...
  7. haidut

    High blood PUFA "a specific feature of severe COVID-19 pneumonia"

    The evidence for PUFA being a crucial pathological factor in yet another disease is probably not surprising to my readers. The reason I like this study is that since COVID-19 is still (unfortunately) the main topic of the day in most Western countries, a study discussing PUFA in a COVID-19...
    • haidut
    • Thread
    • covid-19 inflammation lipolysis mortality pneumonia pufa sars-cov-2
    • Replies: 17
    • Forum: Scientific Studies
  8. haidut

    Inhibiting lipolysis may treat diabetes

    Probably nothing surprising to my readers, but I think the study below is still important as it is one of the very few that openly state that diabetes is driven not by genetics but by excessive free fatty acids in the blood. While it does not mention it directly, the study is a great...
    • haidut
    • Thread
    • diabetes ffa insulin lipolysis nefa obesity randle cycle
    • Replies: 21
    • Forum: Scientific Studies
  9. A

    Why Cancer of the Heart is So Rare

    https://raypeatforum.com/community/threads/cancer-cells-addicted-to-fat-and-use-fat-oxidation-for-survival.7639 https://raypeatforum.com/community/threads/forcing-the-heart-to-burn-glucose-instead-of-fat-may-cure-heart-failure.33094 Dr. Stephen Hussey To understand why cancer in the heart is...
    • aliml
    • Thread
    • cancer fatty acid oxidation heart lipolysis
    • Replies: 11
    • Forum: Cancer
  10. A

    Link Between Spinal Muscular Atrophy and Fatty Acid Metabolism

    Spinal muscular atrophy (SMA) is an autosomal recessive condition that results in pathological deficiency of the survival motor neuron (SMN) protein. SMA most frequently presents itself within the first few months of life and is characterized by progressive muscle weakness. As a neuromuscular...
  11. haidut

    How lipolysis may damage organs such as the heart

    It is well-known in endocrinology, and especially among doctors specializing in diabetes, that excessive lipolysis is highly detrimental not only for the overall progression of metabolic diseases like diabetes, but also for most of the organs of the patient. Lipolysis is known to be elevated in...
    • haidut
    • Thread
    • adipocytes debris fibrosis heart lipolysis mitochondria ros
    • Replies: 0
    • Forum: Scientific Studies
  12. T

    OEA, maybe my favorite supplement?

    Recently I started taking Oleoylethanolamide or OEA from science.bio. This ***t is life changing. A supplement you can truly feel. It acts on the endocannabinoid system and is very similar to anandamide. I feel euphoria, relaxation, and just overall happiness and well being when I take it...
  13. haidut

    Stress-driven lipid peroxidation, inflammation re-awakens dormant cancer cells

    Yet another study demonstrating that stress is anything but benign or irrelevant for chronic diseases, especially for cancer. The study below demonstrates that stress-induced increases of epinephrine and norepinephrine results in increased lipolysis and a cascade of pro-carcinogenic downstream...
    • haidut
    • Thread
    • beta blocker cancer dormant inflammation lipolysis peroxidation pufa stress
    • Replies: 0
    • Forum: Scientific Studies
  14. haidut

    Keto Diet Can Cause Lethal Kidney Failure

    The bad news for the low-carb diets just keep piling on. This case report is about a young and (presumably) healthy Indian actress, which quickly deteriorated and eventually died of kidney failure while subjecting herself to the keto diet. Before the hate mail starts pouring into my mailbox...
    • haidut
    • Thread
    • ffa high-fat keto ketosis kidney lethal lipolysis low-carb
    • Replies: 5
    • Forum: Scientific Studies
  15. haidut

    PUFA Exacerbate, Saturated Fats (SFA) / Albumin / Calcium Ameliorate COVID-19

    A few months ago I posted about a study discussing the role of lipid peroxidation in the COVID-19 pathology. While that study did not make any statements about effects of diet on the disease course/outcome, it did suggest lipid peroxidation blockers such as vitamin E would be therapeutic. Now...
    • haidut
    • Thread
    • albumin calcium covid-19 lipolysis pancreatitis peroxidation pufa sfa
    • Replies: 3
    • Forum: Scientific Studies
  16. haidut

    Lipolysis / FFA Drive Breast Cancer By Promoting Estrogen Signalling

    The evidence for the fat-loving nature of cancer just keeps on accumulating. During the last podcast with Danny and Ray, I mentioned that in cancer cells the enzyme fatty acid synthase (FAS) is actually part of the estrogen receptor (ER) complex. As such, anything that increases the...
    • haidut
    • Thread
    • breast cancer estrogen fao fatty acid oxidation ffa lipolysis nefa randle cycle
    • Replies: 0
    • Forum: Scientific Studies
  17. haidut

    SFA / MUFA Are Preferentially Oxidized, While PUFA Are Stored/accumulated

    Just a quick post in response to some of the hate mail I keep getting on a daily basis in regards to the body's discriminatory treatment of various fat types. According to various proponents of keto diets, fasting, etc the organism has no preference for one type of fat or another in terms of...
    • haidut
    • Thread
    • diet disease esterification fasting high-fat lipolysis low-carb mufa oxidation preference pufa sfa storage stress
    • Replies: 14
    • Forum: Scientific Studies
  18. haidut

    Stress (epinephrine And Lactate) Cause Tumor Growth, Vitamin C Stops It

    Yet another study linking chronic stress to cancer growth. I posted several threads in the past demonstrating the negative effects epinephrine and lipolysis on cancer cell growth and how administering a beta blocker can inhibit the growth of tumors. Stress (adrenaline, Noradrenaline) As The Main...
    • haidut
    • Thread
    • activate ascorbic acid cancer chronic stress cure linus pauling lipolysis stem cells stress treat tumor vitamin c
    • Replies: 48
    • Forum: Scientific Studies
  19. haidut

    Fatty Acid Oxidation (FAO) Makes Cancer Therapy-resistant, Niacinamide May Help

    Yet another study that shows FAO playing a crucial role in cancer progression. As many forum users know, anti-angiogenic therapies are one of the cornerstones of current cancer treatments. This therapy typically uses the so-called VEGF inhibitors to block the formation of new blood vessels in...
    • haidut
    • Thread
    • angiogenesis cancer cpt1 fatty acid oxidation hypoxia inhibitor lipolysis metastasis mildronate niacinamide progression tumor vegf
    • Replies: 0
    • Forum: Scientific Studies
  20. haidut

    Stress (adrenaline, Noradrenaline) As The Main Driver Of Cancer Metastases

    I just posted a study in which it was shown that surgical removal of a tumor results in massive and uncontrolled formation of metastases across the entire organism. Universal Test For Cancer Progression/stage Here is the quote again, just to make the point of this thread clear. "...The...
    • haidut
    • Thread
    • adrenaline beta-blocker cancer epinephrine fatty acid oxidation growth increase lipolysis metastases noradrenaline norepinephrine stimulate stress
    • Replies: 8
    • Forum: Scientific Studies
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