lipolysis

  1. haidut

    How lipolysis may damage organs such as the heart

    It is well-known in endocrinology, and especially among doctors specializing in diabetes, that excessive lipolysis is highly detrimental not only for the overall progression of metabolic diseases like diabetes, but also for most of the organs of the patient. Lipolysis is known to be elevated in...
  2. D

    OEA, maybe my favorite supplement?

    Recently I started taking Oleoylethanolamide or OEA from science.bio. This ***t is life changing. A supplement you can truly feel. It acts on the endocannabinoid system and is very similar to anandamide. I feel euphoria, relaxation, and just overall happiness and well being when I take it...
  3. haidut

    Stress-driven lipid peroxidation, inflammation re-awakens dormant cancer cells

    Yet another study demonstrating that stress is anything but benign or irrelevant for chronic diseases, especially for cancer. The study below demonstrates that stress-induced increases of epinephrine and norepinephrine results in increased lipolysis and a cascade of pro-carcinogenic downstream...
  4. haidut

    Keto Diet Can Cause Lethal Kidney Failure

    The bad news for the low-carb diets just keep piling on. This case report is about a young and (presumably) healthy Indian actress, which quickly deteriorated and eventually died of kidney failure while subjecting herself to the keto diet. Before the hate mail starts pouring into my mailbox...
  5. haidut

    PUFA Exacerbate, Saturated Fats (SFA) / Albumin / Calcium Ameliorate COVID-19

    A few months ago I posted about a study discussing the role of lipid peroxidation in the COVID-19 pathology. While that study did not make any statements about effects of diet on the disease course/outcome, it did suggest lipid peroxidation blockers such as vitamin E would be therapeutic. Now...
  6. haidut

    Lipolysis / FFA Drive Breast Cancer By Promoting Estrogen Signalling

    The evidence for the fat-loving nature of cancer just keeps on accumulating. During the last podcast with Danny and Ray, I mentioned that in cancer cells the enzyme fatty acid synthase (FAS) is actually part of the estrogen receptor (ER) complex. As such, anything that increases the...
  7. haidut

    SFA / MUFA Are Preferentially Oxidized, While PUFA Are Stored/accumulated

    Just a quick post in response to some of the hate mail I keep getting on a daily basis in regards to the body's discriminatory treatment of various fat types. According to various proponents of keto diets, fasting, etc the organism has no preference for one type of fat or another in terms of...
  8. haidut

    Stress (epinephrine And Lactate) Cause Tumor Growth, Vitamin C Stops It

    Yet another study linking chronic stress to cancer growth. I posted several threads in the past demonstrating the negative effects epinephrine and lipolysis on cancer cell growth and how administering a beta blocker can inhibit the growth of tumors. Stress (adrenaline, Noradrenaline) As The Main...
  9. haidut

    Fatty Acid Oxidation (FAO) Makes Cancer Therapy-resistant, Niacinamide May Help

    Yet another study that shows FAO playing a crucial role in cancer progression. As many forum users know, anti-angiogenic therapies are one of the cornerstones of current cancer treatments. This therapy typically uses the so-called VEGF inhibitors to block the formation of new blood vessels in...
  10. haidut

    Stress (adrenaline, Noradrenaline) As The Main Driver Of Cancer Metastases

    I just posted a study in which it was shown that surgical removal of a tumor results in massive and uncontrolled formation of metastases across the entire organism. Universal Test For Cancer Progression/stage Here is the quote again, just to make the point of this thread clear. "...The...
  11. haidut

    Cancer Is A State Of Chronic Stress With Elevated Lipolysis And Ketogenesis

    I am posting this study because it invalidates one of the central dogmas of modern oncology - i.e. that cancer is a localized, organ-specific disease that is best handled by attacking/destroying/removing the affected organ/tissue. Most doctors would flatly deny/reject the statement that a cancer...
  12. haidut

    Inhibiting Lipolysis May Treat / Cure Cancer

    I posted a number of threads over the last 6 months that show cancer's appetite for fat and how inhibiting fatty acid oxidation or transport into the cell can have dramatic therapeutic results even for highly lethal malignancies like pancreatic cancer. Triple-Negative Breast Cancers Depend On...
  13. P

    Manganese Mimics Insulin

    -manganese increases co2 production from glucose -inhibits lipolysis -increases lipogenesis Regulation of glucose utilization and lipogenesis in adipose tissue of diabetic and fat fed animals: effects of insulin and manganese. - PubMed - NCBI
  14. Hugh Johnson

    Indomethacin But Not Aspirin Inhibits Basal And Stimulated Lipolysis In Rabbit Kidney

    http://www.ncbi.nlm.nih.gov/pubmed/7465862
  15. N

    Inhibition of Lipolysis Improves Glucose Metabolism, Insulin Sensitivity w/o Altering Fat Mass

    Not really news for Peat followers but this study might give a hint on what happens when we suppress lipolysis e.g. via Niacinamide: http://www.plosbiology.org/article/info ... io.1001485 When energy is needed, white adipose tissue (WAT) provides fatty acids (FAs) for use in peripheral tissues...
  16. managing

    DHEA and lipolysis

    RP has been widely cited as recommending very small doses (2-3mg) of DHEA for diabetics. Presumably, this is to prevent low BG problems. But DHEA acts through lipolysis. http://www.ncbi.nlm.nih.gov/pubmed/18063002 http://www.ncbi.nlm.nih.gov/pubmed/7611511 Is it simply a lesser of two evils...
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