Collagen accumulates with aging and causes fibrosis. Although this study only highlights aged donors, it shows that lidocaine antagonizes the pro-fibrotic effects of IGF-1, TGF Beta-1, collagen proteins and inhibits collagen accumulation.
Lidocaine impairs proliferative and biosynthetic...
Effect of lidocaine on bone matrix formation by osteoblasts
Effect of lidocaine on bone matrix formation by osteoblasts
Srinivas Pentyala*, Emily Hughes, Pooja Mysore, Supriya Mishra, Julie Miller, Aleef Rahman and Kyle Urbanczyk
Correspondence: Srinivas Pentyala...
Antioxidant effect of lidocaine and procaine on reactive oxygen species-induced endothelial dysfunction in the rabbit abdominal aorta
Korean J Anesthesiol. 2010 Aug; 59(2): 104–110.
Published online 2010 Aug 20. doi: 10.4097/kjae.2010.59.2.104
PMCID: PMC2926425
Antioxidant effect of lidocaine...
Effect of inhaled and intravenous lidocaine on inflammatory reaction in endotoxaemic rats. - PubMed - NCBI
Eur J Anaesthesiol. 2010 Jan;27(1):53-60. doi: 10.1097/EJA.0b013e32832b8a70.
Effect of inhaled and intravenous lidocaine on inflammatory reaction in endotoxaemic rats.
Flondor M1, Listle...
Comparison of the Antibacterial Activity of Lidocaine 1% Versus Alkalinized Lidocaine In Vitro
Local anesthetics as antimicrobial agents: a review. - PubMed - NCBI
ANTIBACTERIAL PROPERTIES OF 2% LIDOCAINE AND REDUCED RATE... : RETINA
Nebulized lidocaine inhalation in the treatment of patients with acute asthma
World J Emerg Med. 2011; 2(1): 30–32.
PMCID: PMC4129744
Nebulized lidocaine inhalation in the treatment of patients with acute asthma
Zu-ming Lv, Li Chen, and Jie Tang
Author information ► Article notes ► Copyright...
Cluster headache with ptosis responsive to intranasal lidocaine application: a case report. - PubMed - NCBI
J Med Case Rep. 2012 Feb 15;6:64. doi: 10.1186/1752-1947-6-64.
Cluster headache with ptosis responsive to intranasal lidocaine application: a case report.
Bakbak B1, Gedik S, Koktekir...
Antiarrhythmic effect of magnesium sulfate after open heart surgery: effect of blood levels. - PubMed - NCBI
Int J Cardiol. 2003 Jun;89(2-3):153-8.
Antiarrhythmic effect of magnesium sulfate after open heart surgery: effect of blood levels.
Kiziltepe U1, Eyileten ZB, Sirlak M, Tasoz R, Aral...
Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro
http://bja.oxfordjournals.org/content/early/2012/04/26/bja.aes128.full
I wonder if chronic oral intake could reverse gene methylation.