The study itself has a misleading title because there are quite a few situations that can result in lower brain pH (and thus high acidity). High...
The enzyme pyruvate dehydrogenase (PDH) is perhaps the single most important factor in proper glucose metabolism and it is often severely...
This is a great study since it directly highlights the metabolic connection between excess lactic acid and cancer. Thiamine deficiency results in...
Do not forget to give thiamine to your septic shock patient!Thiamine was the first B vitamin to be identified and is also referred to as vitamin...
Hormonal responses from concentric and eccentric muscle contractions. - PubMed - NCBIAbstract Intense resistance exercise can acutely increase...
The good things about this study is that it is human and as such the doses are directly relevant. Given that the patient had MELAS, the...
Russian study, so I can't get the actual paper and see route of administration, but it was likely oral or intraperitoneal. Human equivalent dosage...
The study was with humans and also included exercise, which makes thiamine even more interesting to athletes. The type of thiamine used was TTFD,...
Ray has written a lot on the toxicity of lactate and how it is not just a harmless metabolite. However, modern medicine treats lactate not just as...
This study lists some of the possible reasons drugs like Metformin are to be avoided and why Peat has cautioned against it even without explicitly...
A nice study that ties together the hypoglycemic state of shock with increased levels of lactate and pyruvate - all caused by adrenalin....
Beta-alanine is the limiting substrate for the production of Carnosine. Carnosine (not carnitine) is the primary intracellular buffer for lactate....
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