Chronic alcohol abuse is highly detrimental to health and especially to the brain. Alcohol puts the body in a reductive state and depletes vitamin B1 (thiamine) stores. If the B1 deficiency becomes severe enough it manifests through what is clinically known as Wernicke-Korsakoff syndrome (WKS)...
Recently I bought some Cyproheptadine and Vitamin B Complex syrup and I noticed it contained some 0.08 grams of Ferric Pyrophosphate for every 1mg of Cypro
Given that I'm planning to start taking the cypro regularly I wanted to know if there was potential danger given what Peat has to say about...
Hey guys,
In my head this is a 1+1=2 anecdote, but it requires a few sentences of context.
Summarized conclusion: about 450 calories of 100% dark chocolate reversed symptoms of fatigue and lack of motivation.
___________
For the last few weeks, something like 80% of my calories have come from...
I wonder if the mechanism by which vitamin C helps Covid-19 infected patients is by regulating iron in the body, reducing ferritin, and thus preventing lipid peroxidation.
Hemoglobin, myoglobin and heme compounds can accelerate lipid peroxidation by at least two different mechanisms: the heme...
As the study itself states, it is not just the iron used in dietary supplements that may the dangerous. The type used on food fortification is just as dangerous and may be even more impactful since virtually all people eat commercial food on a daily basis while much fewer numbers consume iron...
17β-Estradiol Inhibits Iron Hormone Hepcidin Through an Estrogen Responsive Element Half-Site
”Hepcidin is the central regulatory molecule of systemic iron homeostasis (5). In this study, we found that hepcidin mRNA is inhibited in cells and in mice by nanomolar concentrations of E2 (Figs. 2...
Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with mal... - PubMed - NCBI
we found positive correlations between the concentrations of TT-Mg, TT-Fe, TT-Mo, FT-Fe,
So iron has a positive correlation...
Has anyone here ever attempted to cure type 2 diabetes successfully?
A friend just started diabetes medication, and in a party we were in, he passed out because the medication made his blood sugar go way low. I told him I'll see if I can provide a method where he can get his condition cured...
By this time we are all aware that iron should be kept low. In this study iron is involved in insulin resistance, inflammation and fat gain.
Iron homeostasis: a new job for macrophages in adipose tissue?
"men and women in the highest quintile of serum ferritin (Ft) levels – the primary...
I posted a few recent studies that finally start to make the connection between endotoxin, iron, and neurodegenerative conditions.
Endotoxin And Iron Finally Recognized As Potential Causes Of Many Diseases
Endotoxin (LPS) May Be A Causative Factor In Alzheimer Disease (AD)
Big Pharma is...
Everyone is familiar with Ray's writings on the dangers of iron, and we're all accustomed to the idea of its moderate restriction. However, in some situations such as infections, a strict avoidance can also be beneficial, especially if there are antibiotics involved. In fact, if the forum had a...
Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with m... - PubMed - NCBI
Abstract
Beyond 30 years of age, men experience a decline in the production of testosterone, yet only a few develop late-onset...
Adipocyte iron regulates adiponectin and insulin sensitivity. - PubMed - NCBI
Iron overload is associated with increased diabetes risk. We therefore investigated the effect of iron on adiponectin, an insulin-sensitizing adipokine that is decreased in diabetic patients. In humans, normal-range...
The optimal approach would be to keep iron stores on the low end of normal but for the people who already have confirmed iron overload, this study may offer some help. Glycine seems to protect from the toxicity of iron, which is mainly manifested in the liver (and sometimes brain).
Iron induces...
Hi All,
This article I wrote won't be new to long-time Peaters, but my journey continues to remind me how important it is to avoid Iron in my diet. I've discovered a few tricks like eating foods high in manganese, using cilantro, as well as citrus away from iron-heavy foods to quickly reduce...
Effects of excess dietary iron and fat on glucose and lipid metabolism. - PubMed - NCBI
Abstract
PURPOSE:
Diets rich in fat and energy are associated with metabolic syndrome (MS). Increased body iron stores have been recognized as a feature of MS. High-fat diets (HFs), excess iron loading and...
Battles with Iron: Manganese in Oxidative Stress Protection
Abstract
The redox-active metal manganese plays a key role in cellular adaptation to oxidative stress. As a cofactor for manganese superoxide dismutase or through formation of non-proteinaceous manganese antioxidants, this metal can...
Vitamin D3 transactivates the zinc and manganese transporter SLC30A10 via the Vitamin D receptor. - PubMed - NCBI
Vitamin D3 regulates genes critical for human health and its deficiency is associated with an increased risk for osteoporosis, cancer, diabetes, multiple sclerosis, hypertension...
Micronutrient intakes of wild primates: are humans different? - PubMed - NCBI
Abstract
Low micronutrient intake is implicated in a diversity of human health problems, ranging from problems associated with food insufficiency to those associated with food over-consumption. Humans are members of...