insulin

  1. RealNeat

    Cell Free Mitochondria?

    Researchers Find Cell-Free Mitochondria Floating in Human Blood what do we suppose is the reasoning behind this? Does it in some way expand upon, microvesicles, exosomes, cell to cell communication? Or is it just remnants of the "life cycle" of a blood cell.
  2. Tarmander

    Gut Protocol For Insulin Resistance, Metabolism, And Energy

    I wanted to share this amazing gut protocol that I have been on for the last few months (results below) I am in a unique position as a type 1 diabetic in that my pancreas produces little to no insulin on its own. This gives me an insight into what supplements and herbs do to insulin needs in...
  3. haidut

    Blocking Endotoxin (LPS) May Reverse/cure Diabetes Type I

    Yet another study demonstrating the key role of endotoxin in the pathology of perhaps the most widespread chronic disease - diabetes. The study below discovered that the proliferation of the insulin-producing beta-cells in the pancreas is controlled almost entirely by the TLR4/TLR2 receptor...
    • haidut
    • Thread
    • beta-cells cause diabetes endotoxin inflammation insulin lps pancreas tlr tlr2 tlr4
    • Replies: 5
    • Forum: Scientific Studies
  4. P

    “NO” To Autophagy: Fat Does The Trick For Diabetes

    “NO” to Autophagy: Fat Does the Trick for Diabetes During the progression from obesity to diabetes, a critical attribute is inability to maintain metabolic homeostasis under excessive energy and nutrient exposure, which triggers insulin resistance. Intensive research efforts have linked chronic...
    • paymanz
    • Thread
    • autophagy diabetes hyperinsulinemia inflammation insulin insulin sensitivity mitophagy nitric oxide obesity tlr4
    • Replies: 0
    • Forum: Articles & Scientific Studies
  5. nigma

    Potassium Or Insulin As The 'insulin' Effect

    There is a somewhat well known idea of Ray's that says insulin plays a smaller part in the insulin effect than insulin itself. While potassium looks to be the main actor in getting glucose into cells. from 'Glycemia, starch, and sugar in context' "Insulin is important in the regulation of blood...
  6. P

    The Effect Of Training Volume And Intensity On Improvements In Muscular Strength And Size In Resista

    on every parameter high intensity( heavier weight lower reps with longer rest between sets) is superior to high volume exercise , body fat , lean mass, power. also hormones ; cortisol ,T , igf .... everything is better! The effect of training volume and intensity on improvements in muscular...
  7. yerrag

    Protocol For Curing Type 2 Diabetes, Anyone?

    Has anyone here ever attempted to cure type 2 diabetes successfully? A friend just started diabetes medication, and in a party we were in, he passed out because the medication made his blood sugar go way low. I told him I'll see if I can provide a method where he can get his condition cured...
    • yerrag
    • Thread
    • diabetes insulin insulin resistance iron
    • Replies: 82
    • Forum: Blood Sugar
  8. haidut

    Anti-adrenaline Drugs Like Clonidine May Prevent Diabetes Type I

    Peat mentioned a few times that the pancreatic damage seen in type I diabetes is caused by prolonged exposure to PUFA, as unsaturated fats are toxic to the insulin-producing beta cells in that organ. Many of the cases of new onset diabetes I occur after a period of extreme exhaustion and/or...
    • haidut
    • Thread
    • adrenaline autoimmune beta cells clonidine diabetes epinephrine ffa insulin methyldopa pancreas pufa
    • Replies: 10
    • Forum: Scientific Studies
  9. P

    Low Dose Doxycycline Decreases Systemic Inflammation And Improves Glycemic Control, Lipid Profiles,

    Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in <i>db/db</i> mice Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in...
    • paymanz
    • Thread
    • a1c adiponectin advanced glycation end products antiinflammatory apoptosis beta cells diabetes doxycycline endotoxin glycogen inflammation insulin insulin resistance insulin sensitivity lps minocycline mmp inhibitor obesity tetracycline tnf
    • Replies: 5
    • Forum: Articles & Scientific Studies
  10. haidut

    Delirium (and Dementia/AD) Is Caused By Inability To Oxidize Glucose

    Ray has written about the metabolic origins of Alzheimer disease (AD) and I posted quite a few studies on the links between AD and PUFA metabolites as well as insulin resistance in the brain. I even mentioned on one of Danny Roddy's shows that there is a proposal by NIH to reclassify AD as...
    • haidut
    • Thread
    • ad alzheimer's delirium dementia ffa glucose insulin metabolism niacinamide pufa
    • Replies: 7
    • Forum: Scientific Studies
  11. haidut

    A Subset Of Diabetes I Can Be Cured By Vitamin B1 (thiamine)

    I don't know much about this apparently genetic form of neonatal diabetes I, but looking at the mutation in question I do not see how it related to thiamine at all, yet thiamine is therapeutic. So, the question that naturally arises is - can thiamine potentially help all cases of diabetes I...
    • haidut
    • Thread
    • diabetes insulin mutation neonatal reversal thiamine treatment
    • Replies: 12
    • Forum: Scientific Studies
  12. Mito

    A Review Of The Carbohydrate–insulin Model Of Obesity

    European Journal of Clinical Nutrition - A review of the carbohydrate-insulin model of obesity The carbohydrate–insulin model of obesity theorizes that diets high in carbohydrate are particularly fattening due to their propensity to elevate insulin secretion. Insulin directs the partitioning of...
  13. Steven Bussinger

    Insulin Neuroprotection And The Mechanisms

    Insulin Neuroprotection and the Mechanisms Insulin, Neuroprotection, GABA, Glucose, Glycogen, Ischemia, Glutamate Introduction Insulin is the only endocrinology hormone to decrease blood glucose. In addition, insulin serves as a growth factor, modulating mitogenesis, growth, and...
  14. P

    Manganese Mimics Insulin

    -manganese increases co2 production from glucose -inhibits lipolysis -increases lipogenesis Regulation of glucose utilization and lipogenesis in adipose tissue of diabetic and fat fed animals: effects of insulin and manganese. - PubMed - NCBI
  15. haidut

    Androsterone - A Potential Treatment For Insulin Resistance And Diabetes

    In another recent thread, I posted about androsterone's potent thyromimetic effects. Given the ability of thyroid hormone to improve insulin sensitivity and even reverse diabetes type II, it would not be surprising that androsterone would also exhibit such effects. And indeed, androsterone...
    • haidut
    • Thread
    • androsterone diabetes insulin insulin resistance insulin sensitivity type 2
    • Replies: 2
    • Forum: Scientific Studies
  16. Amazoniac

    Potassium Deficiency, Pancreas, Insulin And Glucose Metabolism

    People that kiss with the eyes open to monitor if the surroundings are safe, Effect of experimental potassium deficiency on glucose and insulin metabolism "Our results indicate that mild-to-moderate potassium depletion, of a magnitude commonly encountered in clinical practice, does cause a...
  17. haidut

    Pregnenolone For Blood Sugar Control

    It was recently discovered that the so-called TRM3 "receptors" in the pancreatic beta cells can be activated by pregnenolone sulfate (PS) at relatively low concentrations and result in insulin release. This makes pregnenolone a potential tool for keeping blood sugar levels normal and can also...
    • haidut
    • Thread
    • beta cells blood glucose homeostasis insulin pancreas pregnenolone trm3
    • Replies: 5
    • Forum: Scientific Studies
  18. haidut

    Blood Sugar Is Controlled Mostly By The Brain, Not Pancreas

    Ray wrote in one of his articles that pancreatic insulin is responsible for no more than 20% of glycemic control. While he mentioned potassium as the major factor, he also said that it is the brain that ultimately controls the levels of sugar in the blood. This study from Yale seems to confirm...
    • haidut
    • Thread
    • biogenesis blood brain control insulin mitochondria pancreas sugar uncoupling
    • Replies: 8
    • Forum: Scientific Studies
  19. haidut

    Glycine Powerfully Lowers Cortisol

    I have long suspected that inhibitory amino acids suppress cortisol release. The reason is that most of these inhibitory amino acids like glycine, taurine, beta alanine, theanine, etc are all GABA agonists. GABA agonist pharma drugs are used to treat Cushing syndrome and are very effective at...
  20. haidut

    Plasticisers (bpa, Dehp) Boost Pufa, Estrogen, Cortisol & Block Glucose Oxidation

    While the FDA continues to claim that BPA and other plastic derivatives are harmless since no known mechanism exists to explain their effects, the mechanisms of action have been quite well known for decades. BPA specifically is an estrogen "receptor" agonist more potent than estradiol, AND also...
    • haidut
    • Thread
    • bpa bps cortisol dehp estrogen glucose insulin obesity plastic pufa
    • Replies: 36
    • Forum: Scientific Studies
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