insulin resistance

  1. raypeatclips

    Combined Chromium And Magnesium Decreases Insulin Resistance More Effectively Than Either Alone

    Can't seem to see what type of magnesium they used, as many forms of magnesium are horribly absorbed. I wonder if magnesium alone would have been good if it was a more absorbable type. Combined chromium and magnesium decreases insulin resistance more effectively than either alone. - Abstract -...
  2. haidut

    DHT Lowers Risk Of Diabetes In Older Males

    Most endocrinologists view DHT as an almost exclusively bad hormone. Aside from the its much publicized (and likely incorrect) role in prostate cancer and MPB, endocrinologists consider DHT as a causative agent in insulin resistance and even diabetes type II. Most of that misguided opinion...
    • haidut
    • Thread
    • dht diabetes insulin resistance insulin sensitivity males men older shbg study type 2
    • Replies: 9
    • Forum: Scientific Studies
  3. Bahaa El wazzan

    LOW SALT DIET

    A low salt diet increases the free fatty acids, leading to insulin resistance, increasing free fatty acids in the blood, and contributing to atherosclerosis (Prada, et al., 2000; Mrnka, et al., 2000; Catanozi, et al., 2003; Garg, et al., 2011) Atherosclerosis is a disease in which plaque...
  4. haidut

    Androsterone - A Potential Treatment For Insulin Resistance And Diabetes

    In another recent thread, I posted about androsterone's potent thyromimetic effects. Given the ability of thyroid hormone to improve insulin sensitivity and even reverse diabetes type II, it would not be surprising that androsterone would also exhibit such effects. And indeed, androsterone...
    • haidut
    • Thread
    • androsterone diabetes insulin insulin resistance insulin sensitivity type 2
    • Replies: 2
    • Forum: Scientific Studies
  5. P

    Is Insulin Resistance A Result Of Impaired Beta Oxidation Or Excessive Beta Oxidation?

    Peat's obviously a big believer that healthy glucose metabolism should be favored over beta oxidation, and that many factors, including PUFA, excessive lypolysis, serotonin, estrogen, cortisol, lactate, and inflammation all steer the body away from oxidative metabolism, leading to even more...
  6. P

    Biotin Decreases Serum Free Fatty Acids

    Effects of Biotin Supplementation in the Diet on Adipose Tissue cGMP Concentrations, AMPK Activation, Lipolysis, and Serum-Free Fatty Acid Levels. - PubMed - NCBI Several studies have shown that pharmacological concentrations of biotin decrease hyperlipidemia. The molecular mechanisms by which...
  7. P

    Effects Of Excess Dietary Iron And Fat On Glucose And Lipid Metabolism

    Effects of excess dietary iron and fat on glucose and lipid metabolism. - PubMed - NCBI Abstract PURPOSE: Diets rich in fat and energy are associated with metabolic syndrome (MS). Increased body iron stores have been recognized as a feature of MS. High-fat diets (HFs), excess iron loading and...
    • paymanz
    • Thread
    • diabetes fatty liver high-fat insulin resistance insulin sensitivity iron iron-overload metabolic syndrome study
    • Replies: 5
    • Forum: Articles & Scientific Studies
  8. haidut

    Blue Light Exposure Just Twice A Day Causes Insulin Resistance In Humans

    No need to elaborate, given how much Ray has written about red and blue light and their effects on metabolism. The key result from the study was that just 3 hours of exposure was enough to trigger that metabolic dysfunction. Imagine what happens at night when there is ambient blue light...
    • haidut
    • Thread
    • blue light exposure induces insulin resistance metabolic metabolic disorder metabolic syndrome
    • Replies: 11
    • Forum: Scientific Studies
  9. Dan W

    Caffeine Improving Sugar Handling And Fat Accumulation In Rats

    I finally managed to post a study before Haidut's high-powered laser-guided tracking system could beat me to it. Caffeine Restores Insulin Sensitivity and Glucose tolerance in High-sucrose Diet Rats: Effects on Adipose Tissue The concentrations necessary might not be as high as they sound...
    • Dan W
    • Thread
    • caffeine diabetes insulin resistance insulin sensitivity obesity study
    • Replies: 1
    • Forum: Scientific Studies
  10. Amazoniac

    Potassium Deficiency, Pancreas, Insulin And Glucose Metabolism

    People that kiss with the eyes open to monitor if the surroundings are safe, Effect of experimental potassium deficiency on glucose and insulin metabolism "Our results indicate that mild-to-moderate potassium depletion, of a magnitude commonly encountered in clinical practice, does cause a...
  11. P

    Mike Eades Posted Blog About Negatives Of Pufa, Fadh2:nadh Ratio

    Well, well, Ray Peat wins again. Mike Eades, a low-carb/high-fat blogger, posted on his blog about the increase of PUFA in American diets and it's correlation to obesity. He talked a bit about how PUFA raises the FADH2:NADH ratio, and raises insulin resistance as a result...
  12. J

    High Fat Diet Induced Inflammation, Temperature, And Metabolic Disease

    http://www.cell.com/cell-metabolism/abs ... 50-4131(15)00519-7 "Highlights •Thermoneutral housing accelerates onset of metabolic inflammation •Thermoneutral housing uncouples adipose tissue inflammation from insulin resistance •Atherosclerosis is potentiated in thermoneutral mice...
  13. H

    Why can insulin resistance be consequence of thyroid dysfunction?

    In seeking to educate myself I came across this study which makes some confusing assertions as to the effect of thyroid hormone http://www.hindawi.com/journals/jtr/2011/152850/ Amongst some positive effects it is also claimed that thyroid can: - decrease glycogen storage - increase fatty acid...
    • hmac
    • Thread
    • hyperthyroidism hypothyroidism insulin resistance study thyroid dysfunction
    • Replies: 2
    • Forum: Scientific Studies
  14. Westside PUFAs

    The Inflammatory Syndrome: The Role Of Adipose Tissue Cytokines In Metabolic Disorders Linked To Obe

    "Numerous other inflammatory mediators are produced and potentially secreted into the circulation by adipose tissue (Table 2). Among these, adiponectin (81), resistin (20), acylation-stimulating protein (82), and components of the renin-angiotensin system (83) may be the most important in...
  15. haidut

    Taurine Prevents Insulin Resistance Caused By PUFA

    Taurine prevented both whole-body and hepatic insulin resistance caused by PUFA ingestion, which makes especially relevant for all people on the forum trying to lose weight through lipolysis while the same time keeping their insulin sensitivity intact. Human equivalent dose is about 5g daily...
  16. haidut

    High PUFA Diet Effectively The Same As Diabetes, Aging And Cancer

    This must be one of the most comprehensive and convincing studies I have come across in the last year. Both a human and a rodent study combined into one. Pretty telling as to whether you want to eat high PUFA or glucose. The patients were on a high-fat diet (35% of calories) and the fat was at...
  17. haidut

    Free fatty acids (FFA) as the cause of insulin resistance

    Peat has said this many times, but I think it is nice to see some independent "verification" of that statement, especially given how often it is questioned here on the forum by some. These two studies by the same scientist seem to imply that chronic suppression of free fatty acid elevation...
  18. haidut

    Caffeine Reverses Stress, Insulin Resistance, Hypertension

    I think should clarify some misconceptions about caffeine. Many people are experiencing a stress response to caffeine, and the more studies I see and the more I experiment with friends/family the more I get convinced that the stress response is: 1. Temporary (last no more than 4 days as shown...
    • haidut
    • Thread
    • caffeine hypertension insulin resistance stress study
    • Replies: 181
    • Forum: Scientific Studies
  19. haidut

    Pregnenolone For Obesity And Insulin Resistance

    I wrote in another thread about the history of PCN, which is just a slightly modified proprietary pregnenolone. This study shows that a human equivalent dose of 3.5mg/kg prevented the obesity caused by high-fat diet. The duration of experiment was 7 weeks. Other noteworthy findings were that...
  20. haidut

    Elevated free fatty acid cause insulin resistance

    More evidence for the Peat camp that it is elevated free fatty acids (FFA), not sugar, that causes insulin resistance. This study actually looked at niacin, since it is known to induce insulin resistance. The study confirmed that the freely circulating fatty acids (but not fat levels in muscle)...
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