inflammation

  1. haidut

    Stress Exacerbates Cancer And Speeds Up Its Progression

    The study is only about leukemia, but it adds to other evidence I have posted before on the role of stress in cancer development and progression. Stress (adrenaline, Noradrenaline) As The Main Driver Of Cancer Metastases Bad Environment & Lifestyle (stress) Cause Most Cancers In Western...
    • haidut
    • Thread
    • accelerates cancer cll exacerbates il-16 inflammation interleukin leukemia progression stress tnf
    • Replies: 15
    • Forum: Scientific Studies
  2. haidut

    Saturated Fat (palmitate) Does NOT Activate TLR4

    We must have had hundreds of discussions on this topic on the forum. Some forum users strongly believe that saturated fat (SFA) increases inflammation by binding to and activating the endotoxin (LPS) receptor TLR4. Among all SFA, palmitate is the one most commonly blamed and has been...
    • haidut
    • Thread
    • disease endotoxin inflammation jnk lps obesity palmitate palmitic acid saturated fat sfa tlr4 vindicated
    • Replies: 28
    • Forum: Scientific Studies
  3. haidut

    The Benefits Of Fasting Are Due To Lowering Endotoxin (LPS), Not Less Calories

    As many of you know, the argument for/against fasting has been raging on the forum for several years at this point. While Ray has spoken several times favorably about potentially skipping a meal or two, he has repeatedly said that chronic fasting is not something he recommends due to its...
    • haidut
    • Thread
    • antagonist benefits caloric restriction cr diabetes endotoxin fasting inflammation lps microbiome obesity tlr4
    • Replies: 39
    • Forum: Scientific Studies
  4. haidut

    Aspirin May Prevent / Reduce HIV Infection In Humans

    A few years ago, I posted some studies showing that endotoxin is key in the development of AIDS. Those studies also found that without endotoxin, the HIV poses little risk to (healthy) organisms...
    • haidut
    • Thread
    • aids aspirin endotoxin hiv inflammation low-dose prevent prevention reduce systemic
    • Replies: 6
    • Forum: Scientific Studies
  5. haidut

    Endotoxin Causes (liver) Steatosis, Insulin Resistance And Atherosclerosis

    I know this study was in hepatitis C patients only, but there is nothing about Hep C that would invalidate this finding in the general population too. Quite a few people on the forum reported that when they tried to talk to their doctor about endotoxin and its possible role in their health...
    • haidut
    • Thread
    • atherosclerosis cvd endotoxemia endotoxin hepatitis inflammation insulin resistance liver lps steatosis tlr4
    • Replies: 16
    • Forum: Scientific Studies
  6. haidut

    Elevated PUFA In Blood Drive Metabolic Syndrome And Diabetes

    Some good evidence on the role of PUFA and inflammation in obesity and diabetes. The findings that FFA are elevated in obese people is not surprising and even mainstream medicine has wisened up to that fact. The surprising (for the authors) part was that unsaturated fats were involved in the...
    • haidut
    • Thread
    • diabetes dietary fats inflammation insulin resistance linoleic linoleic acid metabolic syndrome obesity omega-6 pufa unsaturation
    • Replies: 41
    • Forum: Scientific Studies
  7. haidut

    Morphostasis Theory Of Immunity Confirmed - Body Treats Heart Attack Like Viral Infection

    Peat has touched upon his views of the immune system in several articles, mostly related to autoimmune disease. In his view, the role of the immune system is not so much to "attack" foreign pathogens that threaten the organism, but is more akin to sanitation workers who clean up trash and other...
    • haidut
    • Thread
    • atp energetics energy fibrosis heart attack immune system immunity inflammation morphostasis oxidative metabolism oxphos viral infection virus
    • Replies: 8
    • Forum: Scientific Studies
  8. haidut

    Pulmonary Fibrosis May Be Caused By Endotoxin (LPS)

    Ray spoken and written at length about endotoxin (LPS) and its role in virtually all chronic conditions. Mianstream medicine vehemently denies that LPS is an issue, except possibly for people with liver disease. But in thoses cases, the claim is that endotoxin may cause fever and diarrhea but...
    • haidut
    • Thread
    • endotoxin fibrosis inflammation lps pulmonary fibrosis scleroderma systemic sclerosis tlr4
    • Replies: 9
    • Forum: Scientific Studies
  9. haidut

    Simple Body Stretching Reduces Tumor Size By More Than 50%

    As many of you know, stretching is known to increase ATP levels in muscle. The effects is the reverse of the one caused by contracting, which breaks down ATP. User @Such_Saturation posted a study about that and Peat has mentioned it many times as well. Stretch Creates ATP In the Cardenosine...
    • haidut
    • Thread
    • atp cancer growth immune dysfunction immune system inflammation shrink stretching
    • Replies: 41
    • Forum: Scientific Studies
  10. P

    Effect Of Boron On Thymic Cytokine Expression, Hormone Secretion, Antioxidant Functions, Cell Prolif

    Effect of Boron on Thymic Cytokine Expression, Hormone Secretion, Antioxidant Functions, Cell Proliferation, and Apoptosis Potential via the Extrac... - PubMed - NCBI J Agric Food Chem. 2017 Dec 27;65(51):11280-11291. doi: 10.1021/acs.jafc.7b04069. Epub 2017 Dec 18. Effect of Boron on Thymic...
  11. haidut

    PUFA Is Essential For Cancer, Aspirin And/or Blocking Estrogen Therapeutic

    While this study is not something that will come as surprising to the forum members, I decided to post it because it directly points the finger at BOTH omega-6 and omega-3 unsaturated fats as causes of GI and pancreatic cancers. While the study includes the standard "disclaimer" that omega-3...
    • haidut
    • Thread
    • aspirin cancer carcinogenic estrogen estrogen antagonist inflammation omega-3 omega-6 pufa tamoxifen tumor
    • Replies: 6
    • Forum: Scientific Studies
  12. haidut

    Osteoarthritis (OA) Is Driven By Endotoxin, Can Be Completely Reversed

    Unlike rheumatoid arthritis (RA), its "cousin" known as osteoarthritis (OA) is not generally believe to be due to chronic inflammation. The official cause of OA is "unknown" (just like RA) but often cited factors include genetics, excess weight, and advanced age. The study below points the...
    • haidut
    • Thread
    • arthritis endotoxin gut permeability inflammation lipopolysaccharide lps osteoarthritis prebiotic tlr4
    • Replies: 4
    • Forum: Scientific Studies
  13. haidut

    Baking Soda Is A Potent Anti-inflammatory, May Treat Rheumatoid Arthritis (RA)

    The etiology of rheumatoid arthritis (RA) as an inflammatory disease is well-established even in mainstream medicine. However, the current treatments are downright barbaric and involve the potent suppression of the immune system to the point that the patient is at a constant risk of...
    • haidut
    • Thread
    • baking soda chronic kidney disease ckd cure diet inflammation kidney failure ra rheumatoid arthritis sodium bicarbonate spleen systemic treat
    • Replies: 138
    • Forum: Scientific Studies
  14. haidut

    Western Diet Or SFA Strikingly Protective Against Colon Cancer And Mortality

    No, this is not an April's fool joke. Kind of surprising that this study did not make front page news on MSM, but it may be better this way as the study will probably quickly get retracted if it becomes more popular. Several important findings in this study. The first one is probably the...
    • haidut
    • Thread
    • coconut oil colitis colon cancer high-carb high-sucrose inflammation milkfat protective sfa western diet
    • Replies: 7
    • Forum: Scientific Studies
  15. haidut

    Fat Cells Are Mobile, Migrate As Needed To Heal Wounds Or Prevent/treat Infection

    A very interesting study showing that far from being passive and strictly detrimental to health, fat cells are highly mobile and migrate readily through contraction/motility. These cells accumulate in areas with wounds or infection and release beneficial macrophages and peptides to help...
    • haidut
    • Thread
    • contraction cure fat cells infection inflammation macrophages mobile motile peptides treat wound healing
    • Replies: 14
    • Forum: Scientific Studies
  16. haidut

    Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked

    This is one of the unique studies that breaks away from the mainstream dogma that serotonin is the "happy hormone" and increasing it with drugs like SSRI can lead to nothing but goodness. The study not only directly states that past/current SSRI use is a risk for developing diabetes but show how...
    • haidut
    • Thread
    • 5-ht 5-ht3 5-htt diabetes endotoxemia endotoxin inflammation liver disease lps obesity pufa serotonin serotonin transporter sert tlr4
    • Replies: 45
    • Forum: Scientific Studies
  17. P

    Low Dose Doxycycline Decreases Systemic Inflammation And Improves Glycemic Control, Lipid Profiles,

    Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in <i>db/db</i> mice Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in...
    • paymanz
    • Thread
    • a1c adiponectin advanced glycation end products antiinflammatory apoptosis beta cells diabetes doxycycline endotoxin glycogen inflammation insulin insulin resistance insulin sensitivity lps minocycline mmp inhibitor obesity tetracycline tnf
    • Replies: 5
    • Forum: Articles & Scientific Studies
  18. haidut

    Serotonin / PUFA Drive Migraine

    The role of serotonin in migraines is becoming more recognized every day. Unfortunately, SSRI drugs are still being used to treat migraines, but more recent studies found that serotonin antagonists like cyproheptadine or mianserin are much more effective. The study below found that linoleic...
    • haidut
    • Thread
    • aspirin cyproheptadine inflammation migraines prostaglandins pufa serotonin sfa
    • Replies: 14
    • Forum: Scientific Studies
  19. haidut

    Cardenosine - Liquid Product For R&D

    Our new product is finally here and it is "all about the ATP". I mentioned quite a few times on the forum and over email that we plan on releasing an ATP product and people have been asking me about it for the last few months. It seems a very simple task at first but we thought that we can do a...
    • haidut
    • Thread
    • aging atp cancer cardenosine cortisol dopamine infection inflammation inosine ketoproline metabolism oxoproline p5p pyridoxal-5-phosphate pyroglutamate pyroglutamic acid serotonin succinate succinic acid vitamin b6
    • Replies: 408
    • Forum: IdeaLabs
  20. haidut

    Inosine Increases NAD/NADH Ratio And Reduces Systemic Inflammation

    Yet another great study on inosine. It shows that a HED of just 8mg/kg administered just twice daily increased the NAD/NADH ratio by a whopping factor of 15 (see attached screenshot). While inosine itself is neither a precursor to NAD (like niacinamide) nor is it an oxidizing agent, I think its...
    • haidut
    • Thread
    • inflammation inosine nad nad/nadh nadh raio redox homeostasis sepsis
    • Replies: 69
    • Forum: Scientific Studies
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