inflammation

  1. haidut

    Low-dose Aspirin As Treatment For Kidney Disease / Failure

    Just wanted to post here as diabetes is perhaps the most common chronic disease in the world and many diabetes sufferers have kidney disease, which is considered irreversible. However, as this clinical trial states (and as Peat said as well), the kidney damage seems to be due to inflammation...
    • haidut
    • Thread
    • aspirin cox diabetes inflammation kidney disease kidney failure pufa treatment
    • Replies: 20
    • Forum: Scientific Studies
  2. haidut

    B Vitamins As Antidote To Air Pollution

    I hope this news is not taken as an excuse by governments around the world to increase pollution and start distributing B vitamins to the population as treatment. But given the already high pollution in most major cities around the world, taking a B complex vitamin could be a cheap and safe way...
  3. Elchapchapchapo

    Haidut On Insulin Sensitivity / Insulin Resistance

    Insulin resistance is caused by elevated fatty acids (FFA)
  4. haidut

    Aspirin As A Cure For Sepsis

    If the truly wonder-drug properties of aspirin were considered lacking by some medical authorities, now we can add curing sepsis to that list. Sepsis is the leading cause of death in hospitalized patients, regardless of age, condition, treatment, etc. It is largely considered a lost cause once...
    • haidut
    • Thread
    • aspirin caspase inflammation nsaid organ failure sepsis tlr4 treatment
    • Replies: 54
    • Forum: Scientific Studies
  5. haidut

    Low-dose Aspirin Reduces Miscarriage Risk In Women With High Inflammation

    I posted recently about niacinamide being a potential treatment of pre- and -eclampsia. This new study adds aspirin to the list of substances that can help a mother with compromised health carry a baby to term. The benefit seems to be particularly relevant for women with PCOS and diabetes. The...
  6. haidut

    Bladder Dysfunction And Incontinence Likely Due To Endotoxin (TLR4)

    Ray has mentioned a few times over email to people that bladder irritation or even kidney problems are likely due to increased endotoxin load. My urologists friends laugh so hard when I mention this in our discussions, but lately they seem more gloomy than amused. I suspect that this new study...
    • haidut
    • Thread
    • bladder diabetes dysfunction endotoxin incontinence inflammation tlr4
    • Replies: 6
    • Forum: Scientific Studies
  7. P

    Brain Insulin Resistance Identified As Possible New Link Between Alzheimer's Disease, Diabetes

    It says brains inability to burn glucose is responsible for Alzheimer's disease.caused by insulin's resistance in brain, and that probably mediated by inflammation. Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease – PR News...
  8. P

    A Central Role For JNK(inflammation) In Obesity And Insulin Resistance

    A central role for JNK in obesity and insulin resistance. - PubMed - NCBI Obesity is closely associated with insulin resistance and establishes the leading risk factor for type 2 diabetes mellitus, yet the molecular mechanisms of this association are poorly understood. The c-Jun amino-terminal...
  9. P

    Inflammation Mediates Free Fatty Acid-induced Insulin Resistance

    JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes. - PubMed - NCBI Lipid infusion and high fat feeding are established causes of systemic and adipose tissue insulin resistance. In this study, we treated 3T3-L1 adipocytes with a mixture...
  10. P

    The Role Of Dietary Creatine

    The role of dietary creatine. - PubMed - NCBI The daily requirement of a 70-kg male for creatine is about 2 g; up to half of this may be obtained from a typical omnivorous diet, with the remainder being synthesized in the body Creatine is a carninutrient, which means that it is only available...
  11. haidut

    Blocking PUFA Metabolism May Reverse Alzheimer Disease (AD)

    I posted a few studied showing PUFA and its metabolites are strongly involved in AD and brain aging in general. Increased Pufa Oxidation May Be Biomarker For Alzheimers Blocking Inflammation From PUFA Reverses Brain Aging The second link above discussed specifically the inhibition of the...
    • haidut
    • Thread
    • alox15 alzheimer's brain inflammation inhibitor leukotrienes lipoxygenase lox
    • Replies: 11
    • Forum: Scientific Studies
  12. haidut

    Vitamin D Restores Sensitivity To Cortisol

    The so-called "glucocorticoid resistance" is thought be behind a number of degenerative conditions including diabetes, depression, schizophrenia, chronic inflammation, autoimmune conditions, etc. The condition, similar to insulin resistance, is characterized by elevated serum cortisol levels and...
    • haidut
    • Thread
    • calcitriol cholecalciferol cortisol glucocorticoid inflammation resistance sensitivity vitamin d
    • Replies: 18
    • Forum: Scientific Studies
  13. P

    Voluntary Activation Of The Sympathetic Nervous System And Attenuation Of The Innate Immune Response

    Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. - PubMed - NCBI Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervous system attenuates...
    • paymanz
    • Thread
    • adrenaline endotoxin epinehprine flu immune system inflammation meditation stress sympathetic nervous system tnf
    • Replies: 1
    • Forum: Articles & Scientific Studies
  14. P

    Iron Decreases Adiponectin - Phlebotomy(blood Donation),Manganese,zinc,vitamin D Increasing It

    Adipocyte iron regulates adiponectin and insulin sensitivity. - PubMed - NCBI Iron overload is associated with increased diabetes risk. We therefore investigated the effect of iron on adiponectin, an insulin-sensitizing adipokine that is decreased in diabetic patients. In humans, normal-range...
    • paymanz
    • Thread
    • adiponectin blood donation diabetes fatty liver inflammation insulin sensitivity iron iron-overload light therapy lllt manganese nafld tnf vitamin d zinc
    • Replies: 0
    • Forum: Articles & Scientific Studies
  15. haidut

    Low Social Status Damages The Immune System

    I have posted before on the link between status and health and I think user @Such_Saturation also posted a study on reversal of dominant social status leading to serotonergic dominance. This latest study shows that it is the relative difference of social status that matters. So, even though a...
    • haidut
    • Thread
    • chronic stress endotoxin immune system immunity inflammation lps social isolation social status tlr4
    • Replies: 27
    • Forum: Scientific Studies
  16. haidut

    Glycine Can Completely Prevent Esophagus Damage Caused By GERD

    As discussed in another thread by forum member @denise, using PPI drugs is really to no benefit for preventing inflammation of the esophagus and subsequent development of Barret's or even cancer. The GERD damage is based on an inflammatory reaction, as I mentioned in another post. As such, it...
  17. haidut

    Aspirin Is A Janus Kinase (JK) Inhibitor

    The so-called JK inhibitor drugs are all the rage right now for a number of chronic inflammatory conditions including IBD, RA, Lupus, MS, cancer and Alzheimer. This study found that aspirin (salicylic acid) is a potent JK inhibitor and as such relevant for all the conditions mentioned above. Not...
    • haidut
    • Thread
    • ampk aspirin cancer inflammation inhibition inhibitor jak janus jk kinase
    • Replies: 1
    • Forum: Scientific Studies
  18. haidut

    Aspirin Treats Depression By Lowering Cortisol And Inflammation

    This was an animal study but it follows a long thread of other studies and some of them with humans. Unfortunately, so far all of the human studies used aspirin only as an adjuvant but hopefully as new studies like the one below continue to appear the opinion on aspirin will change. Ray has...
    • haidut
    • Thread
    • antidepressant aspirin cortisol crf crh depression inflammation interferon
    • Replies: 9
    • Forum: Scientific Studies
  19. haidut

    Glycine May Treat Type II Diabetes In Humans

    Human study, with a moderate dose of glycine. Ray wrote several times about the usage of gelatin as treatment for even type I diabetes. Unfortunately, the practice was abandoned in the early 20th century in favor of more toxic therapies or insulin injections. This human study shows that a...
    • haidut
    • Thread
    • a1c blood glucose diabetes glycine inflammation study tnf
    • Replies: 29
    • Forum: Scientific Studies
  20. raypeatclips

    Caffeine Decreases Nitric Oxide (NO) , Cox-2 Inhibitor

    Didn't see this posted and is a fairly new study. Also, does anyone any ideas how this relates to endotoxin? I am quite new at looking at studies. Caffeine prevents LPS-induced inflammatory responses in RAW264.7 cells and zebrafish. - PubMed - NCBI " Caffeine decreased the LPS-induced...
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