1. C

    Life-Extension Drug LOY-001 For Dogs Over 40lbs Is Probably A Few Years Away

    https://www.smithsonianmag.com/smart-news/a-new-drug-that-could-extend-dogs-lives-inches-closer-to-approval-180983331/ I would have posted a chemical description but don't see it online yet.
  2. cs3000

    Hesperidin in 1 glass of orange juice reverses sarcopenia, lowers inflammation, & restores IGF-1 (age related muscle loss)

    Cool research as OJ is commonly accessible, nice effect on restoring igf-1 lowering inflammation and reversing muscle loss in aging (and probably myelin repair for brain function too), and its effect is in already aged mice so can be taken later in life for this health boost 1 250ml glass of...
  3. Hans

    Why DHT doesn’t cause hair loss - My response to Kevin Mann

    Kevin Mann attacked me in one of his vids a while ago, saying that DHT is a trash hormone and that I don't know what I'm talking about. He clearly believes that DHT is harmful and that finasteride is awesome, despite a ton of scientific papers and anecdotes showing that DHT is very much needed...
  4. thingsvarious

    I Replace All My Hormones. Here Is What I Learned

    I want to share my journey with hormone replacement because I believe it might be useful to others. Beacuse hormones are extensively talked about here on RPF, I do think that others might benefit from some of the stuff I learned along my way. I am a medical student in my last year. I replace...
  5. haidut

    "Anti-aging" Hormone (hGH) May Actually Shorten Life

    The duo of hGH/IGF-1 does not need an introduction. Hardly a day passes without some ad on TV promoting the latest and greatest product that "naturally boosts" either hGH or IGF-1 levels. The two hormones have an almost perfect correlation - each one inducing the endogenous synthesis of the...
  6. Hans

    The Conversion Of Testosterone To DHT Is IGF-1 Dependent

    Expression of the insulin-like growth factor (IGF) system and steroidogenic enzymes in canine testis tumors "Since the conversion of testosterone in DHT is IGF-1 dependent [20]. The reduction of 5α-reductase expression in Sertoli cell tumors could be a result of the lower IGF-1 expression. In...
  7. P

    The Effect Of Training Volume And Intensity On Improvements In Muscular Strength And Size In Resista

    on every parameter high intensity( heavier weight lower reps with longer rest between sets) is superior to high volume exercise , body fat , lean mass, power. also hormones ; cortisol ,T , igf .... everything is better! The effect of training volume and intensity on improvements in muscular...
  8. P

    Anxiety Correlates To Decreased Blood And Prefrontal Cortex IGF-1 Levels In Streptozotocin Induced D

    Anxiety correlates to decreased blood and prefrontal cortex IGF-1 levels in streptozotocin induced diabetes - ScienceDirect Progesterone treatment decreases traumatic brain injury induced anxiety and is correlated with increased serum IGF-1 levels; prefrontal cortex, amy... - PubMed - NCBI...
  9. P


    Here probably i only post positives about igf1, as ray seeing it generally on reparative ,constructive side.(according to danny roddy,thanks to him) it is interesting most nutrient deficiencies lower igf1 but not GH! Hypothyroids have lower level of igf1 Serum Resistin and Insulin-Like Growth...
  10. E

    IGF1 : IGFBP3 Ratio As A Predictor Of Male Vertex Balding

    Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3. - PubMed - NCBI Useful things to take from this + additional informations : Milk contains IGF-1 but no IGFBP3, thus increasing the ratio of IGF1:IGFBP3 that is predictor of vertex balding...
  11. Amazoniac

    Milky Questions

    Is it possible to interfere with normal levels of vit D with too much calcium from dairy? In the same way that low calcium intake leads to low vit D, wouldn't high calcium intake have the same effect? Or the excess is just easily excreted? I assume it can also interfere with the absorption of...
  12. M

    Any One Skilled In Reading Labs? Experiencing Hairloss, Fatigue, And Weightgain

    im a 35 year old father of three... did paleo a few years ago and lost 30 pound. stopped two years ago b/c i noticed i started losing my hair and not being able to recover from workouts. Since then i have steadily gained all the weight back plus about an extra 20 pounds. i found this page...
  13. Amazoniac

    Igf-1 Reduces Greatly After Milk Fermentation

    Humans, pboy, This study is the one I was reffering to in my unpopular personal thread on cheeses. It looks like fermentation reduces greatly the amount of IGF-1 in milch and this is particularly relevant for those that struggle with acne since it can interfere with skin cell turn-over and...
  14. Amazoniac

    Insulin/IGF-1 Paradox In Aging

    Hi there, Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling http://www.sciencedirect.com/science/ar ... 6809003234 "Ames and Snell dwarf mice lack GH whereas the Little mouse displays a mutation in the GHRH receptor gene [5,7]. GHRKO mice are also characterized by reduced...
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