hif

  1. haidut

    Hypoxia, Nutrient Deficiency Rapidly Rewires Cells For Cancer Metabolism

    One of the earliest observations of Otto Warburg when he studied cancer was that anything that interferes with oxygen supply to the cell effectively caused the cell to become "cancerous". In other words, he opined that cancer was essentially an adaptation to a lack of oxygen, not a mutant gory...
    • haidut
    • Thread
    • cancer deficiency glycolysis hif hypoxia metabolism nutrient oxygen rewire starvation warburg effect yme1l1
    • Replies: 2
    • Forum: Scientific Studies
  2. haidut

    Estrogen As The Main Cause Of Cancer And Its Progression

    I think many of the forum users here know about the infamous study that generated a lot of controversy on "scientific" forums like Reddit. It basically showed that the Warburg Effect (overproduction of lactate) is not just an effect but a direct cause of cancer. So, as the top rated comment on...
    • haidut
    • Thread
    • cancer estrogen estrogen receptor fatty acid oxidation glycolysis hif hif-1 hypoxia lactate lactic acid mitochondria nad/nadh pdh pdk pyruvate randle cycle redox homeostasis warburg cause warburg cycle warburg effect
    • Replies: 18
    • Forum: Scientific Studies
  3. haidut

    No Need For Mutations, Mitochondrial Stress Alone Can Trigger Cancer

    As Ray said, the official story on cancer and many other conditions thought to be genetic is slowly changing. The powers that be won't admit overnight that genetics has little (if anything) to do with cancer, but the evidence for metabolic dysfunction as a cause of cancer is slowly building up...
    • haidut
    • Thread
    • cancer dna hif hif-1 metabolic stress mitochondrial dysfunction
    • Replies: 23
    • Forum: Scientific Studies
  4. haidut

    Caffeine As A Potential Treatment For Cancer

    Ray has written many times about the anti-cancer properties of substances like caffeine and aspirin, but official research has been lagging behind in explaining how these substances work. A few months ago, I posted another study showing that adenosine antagonism reduces hypoxia in cancer cells...
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