hif-1

  1. haidut

    Estrogen As The Main Cause Of Cancer And Its Progression

    I think many of the forum users here know about the infamous study that generated a lot of controversy on "scientific" forums like Reddit. It basically showed that the Warburg Effect (overproduction of lactate) is not just an effect but a direct cause of cancer. So, as the top rated comment on...
  2. haidut

    No Need For Mutations, Mitochondrial Stress Alone Can Trigger Cancer

    As Ray said, the official story on cancer and many other conditions thought to be genetic is slowly changing. The powers that be won't admit overnight that genetics has little (if anything) to do with cancer, but the evidence for metabolic dysfunction as a cause of cancer is slowly building up...
  3. haidut

    Hypoxia Biomarker HIF-1 Is A Master Inhibitor Of Metabolism

    In another confirmation of Peat's ideas, this human study demonstrates that hypoxia, through increased levels of HIF-1 directly inhibit oxidative metabolism and activate the enzyme pyruvate dehydrogenase kinase (PDK). PDK inhibits the oxidation of pyruvate by inhibiting the enzyme pyruvate...
  4. haidut

    Inhibiting Hypoxia Biomarker (HIF-1) Reverses Parkinson Disease

    Ray has written a lot about HIF-1 and its role in cancer and heart disease. It looks like this biomarker of hypoxia is implicated in the energetic deficits underlying Parkinson disease. Blocking HIF-1 reversed the Parkinson pathology. Caffeine, methylene blue, aspirin and CO2 all inhibit the...
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