heart failure

  1. haidut

    Reduced pyruvate and/or increased lactate drive heart failure

    I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate in the pathogenesis of glaucoma. Just minutes later, another study popped up in my newsfeed. Namely, a study that demonstrates the exact same metabolic disturbances as the main drivers of...
  2. haidut

    Forcing The Heart To Burn Glucose Instead Of Fat May Cure Heart Failure

    One of the blockbuster studies I have seen over the last 12 months. It reads as if written by Peat himself and discusses tissue regeneration, Randle cycle, dietary control of metabolism, etc. AFAIK this is the first study brave enough to demonstrate that simply switching fuel types in an...
  3. haidut

    PUFA (metabolites) Drive Heart Failure And Possibly Diabetes

    Over the years I have posted a number of studies on the roles of PUFA metabolites such as prostaglandins and leukotrienes in many chronic conditions including cancer, Alzheimer, Parkinson, ALS, MS, CVD, etc. For those that are new to this issue, COX enzymes are responsible for prostaglandin...
  4. haidut

    Vitamin D Deficiency Can Cause Heart Failure

    As many readers know, there is an epidemic of vitamin D deficiency. It is of worldwide proportions, but is visible mainly in "developed" countries in the Western world. The official stance of mainstream medicine is that while vitamin D deficiency is undesirable, it does not really have much...
  5. haidut

    Heart Failure Deaths On The Rise In Younger US Adults

    The bad news for younger Americans just keep on coming. In addition to lethal cancers, diabetes, stroke, CVD, infertility, etc now we can add yet another "old man" disease to the list of banes inflicting the "young". The "Young" Have Now Become The Old Heart failure is a condition traditionally...
  6. haidut

    PUFA As The Main Cause Of Cardiovascular Disease (CVD) And Organ Failure

    Some more evidence on the role of PUFA as a big factor in CVD. While the evidence is not widely discussed on mainstream media, and a few saboteur attempt against coconut oil have recently been published, nonetheless a few "runaways" do make it to front page news and we have posted them on the...
  7. haidut

    Standing At Work May Be A Lot More Dangerous Than Sitting

    I am sure many people here have seen the flood of ads for "standing desks" - a raised desk without a chair which a person uses to work in an upright position instead of sitting. Thee have been many health claims made for these desks, none of which have been verified so far in controlled studies...
  8. haidut

    Another "obesity Paradox" - It Lowers Mortality In Patients With Atrial Fibrillation

    I hope this is not taken as a call to get obese. I am posting it simply as an example that obesity may be a protective mechanism once a disease is already established. As such, it should not be viewed always in a negative light but as a possible result of an endocrine disorder, which likely...
  9. haidut

    NSAID Other Than Aspirin Strongly Increase Risk Of Cardiac Arrest, Heart Failure, And Stroke

    It has been know for at least 20 years that taking NSAID drugs other than aspirin increases risk of heart problems. The risk was considered low and even if materialized it was thought it would lead to relatively low grade heart attacks. However, this new study shows that the risk is higher than...
  10. haidut

    Proton Pump Inhibitors (PPI) Increase All-cause Mortality And Heart Failure

    I posted a few studies before on the terrible side effects of PPI drugs. These drugs are perhaps the most prescribed class of drugs in the Western world for conditions like GERD, ulcers, or even to prepare for routine surgery. Recently, these drugs were approved even for use in newborns...
  11. Drareg

    The Relation Between The Low T3 Syndrome In The Clinical Course Of Myocardial Infarction And Heart F

    Abstract It has been proven that either excess or deficiency of thyroid hormones has harmful influence on the cardiovascular system function. On the other hand, severe systemic conditions like myocardial infarction or severe heart failure may affect thyroid hormones secretion and their...
  12. Giraffe

    Blood Pressure Regulation, Heart Failure And Muscle Atrophy - Kmud, 2012-07-20

    Download link for the audio file: http://dl.dropbox.com/u/22195338/Blood Pressure Regulation Heart Failure and Muscle Atrophy.mp3
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