heart disease

Yet another damning study on the toxic effects of drugs whose main effect (lowering cholesterol by blocking its synthesis) is already known to be harmful and has no evidence behind its claimed benefits. So, we can now add diabetes to the list of cancer, ALS, dementia, birth defects...

Some more evidence on the role of PUFA as a big factor in CVD. While the evidence is not widely discussed on mainstream media, and a few saboteur attempt against coconut oil have recently been published, nonetheless a few "runaways" do make it to front page news and we have posted them on the...

As many of you know arterial stiffness is one of the main signs of CVD and contributes significantly to both elevations of blood pressure (BP) and actual ischemic events in brain/heart. According to official guidelines, arterial stiffness cannot be reversed once it sets in, and the only recourse...

This is one of the most comprehensive reviews that I have ever come across on the topic of androgens and their role in male health. It is authored by one of the most renowned experts in urology - the former director of the Department of Urology at Boston University (BU) School of Medicine. Given...

In one of his newsletter circa 2015, Ray wrote about the role of aldosterone in heart failure, heart attacks, shock, and edema. He conjectured that aldosterone antagonists would one day be recognized as therapeutic for these conditions. Almost all types of heart disease start with vascular...

Ray has written about the role of low copper, high serotonin, and generally low thyroid function in changing hair color from dark (or blonde) into white with advancing age. It just so happens, that these phenomena also affect heart health. I have long suspected that premature greying of hair on...

This article appeared in BMJ. Surprisingly, it made front page headline news in our hospital's news section, where I work. Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data | The BMJ

I think we will be seeing more and more of these "breaking news" on major news outlets as the house of cards made of PUFA slowly crumbles. The FDA already reversed its official recommendations on cholesterol, but left the policies on saturated fat intact even though the same study on which the...

Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes. - PubMed - NCBI BACKGROUND: Positive associations have been observed between cardiovascular disease (CVD) and type 2 diabetes mellitus (DM), but their causal relationship has not been clarified. Nevertheless...

I highly recommend reading the full article, there is a lot of information and advice on that site. Some excerpts: What is a reference range? Changing the reference range. The two sides of the public debate ...... Wartofsky & Dickey, "Controversy in Clinical Endocrinology: The...

In some of his recent emails to people Ray recommended pregnenolone as a substance that lowers prostaglandins and inflammation. This mechanism of action also happens to be the officially proposed one for the benefits in heart disease seen with aspirin use. I was looking for the studies to...

The study looked at carriers of a specific variant of the gene CPS1 and the control this gene exerts over specific metabolites. Carriers of this gene variant had significantly increased glycine levels in the blood and lower levels of urea cycle metabolites, especially citrulline (which is a...

http://www.medicaldaily.com/key-longer-life-spermidine-found-cheese-and-semen-extends-lifespan-mice-and-404464 http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4222.html Aging is associated with an increased risk of cardiovascular disease and death. Here we show that oral...

Excess Linoleic Acid Increases Collagen I/III Ratio and “Stiffens” the Heart Muscle Following High Fat Diets Abstract Controversy exists on the benefits versus harms of n-6 polyunsaturated fatty acids (n-6 PUFA). Although n-6 PUFA demonstrates anti-atherosclerotic properties, survival...

The relation of lipid peroxidation processes with atherogenesis: a new theory on atherogenesis. - PubMed - NCBI "The extremely high sensitivity of polyunsaturated fatty acids (PUFAs) to oxygen is apparently used by nature to induce stepwise appropriate cell responses. It is hypothesized that...

FDA has recently made a 180-degree turn in regards to dietary cholesterol. After decades of claiming eating cholesterol gives you heart attacks, now the FDA says that at best it does not matter. This study goes a step further in confirming Peat's views and found that people with the lowest LDL...

Comparisons with treatment with niacin to raise HDL and lower LDL has been considered the gold-standard for all new statin drugs. However, it has been shown that both niacin and niacinamide have the same protective effects on cardiovascular disease (CVD) despite the fact that niacinamide has...