glycolysis

Another study sent to me by the Austrian collaborator. Once again, the energetic origin of "incurable" diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic...

A great study illustrating the crucial effects of metabolism even in "non-metabolic" conditions like COVID-19. We already have evidence that increased PUFA peroxidation is one of the causes behind the (often lethal) cytokine storm in viral diseases, including COVID-19. However, the direct...

One of the earliest observations of Otto Warburg when he studied cancer was that anything that interferes with oxygen supply to the cell effectively caused the cell to become "cancerous". In other words, he opined that cancer was essentially an adaptation to a lack of oxygen, not a mutant gory...

I made a few posts in the past about ALS characterized by adrenal hyperactivity and suppressed gonadal function, as well as mitochondrial dysfunction and copper deficiency. Also, non-familial ALS is known to occurs 4-5 times more often in active/retired elite athletes. All of these findings...

As many readers know, using baking soda to treat cancer has been labelled as "quack medicine" by many official mouthpieces of mainstream medicine, as well as by several "watchdog" groups. Here are some links "debunking" the usage of baking soda for cancer...

I think many of the forum users here know about the infamous study that generated a lot of controversy on "scientific" forums like Reddit. It basically showed that the Warburg Effect (overproduction of lactate) is not just an effect but a direct cause of cancer. So, as the top rated comment on...

Yet another absolutely great study on inosine. It shows that not only can inosine replenish ATP (as shown in the previous studies I posted) but it can inhibit excessive glycolysis, lower lactate, and dramatically improve oxidative metabolism - effects which are key driver of cell differentiation...

If this is indeed true I am not sure how can modern medicine continue to deny the primary role of metabolism in the human organism. The picture so far suggests that metabolism appeared first, then RNA and finally DNA. The same group published two studies. The first one showed that glycolysis can...

Yet another disease likely to be metabolic in origin. In an animal model scientists seemingly cured lupus by blocking glycolysis and also mitochondrial metabolism of specific immune system cells. Given that the drug used to block mitochondrial metabolism was metformin, it is yet another reason...

Ray has written several times about calorie restriction and I am a bit confused on his views. On one end he says that restricting calories enhances metabolism, on the other hand he says it is bad b/c it lowers thyroid hormone and promotes fatty acid oxidation, which is a hallmark of stress...

This is all over the scientific forums, including sites like Reddit. The bottom line is this - after about 100 years of denial, modern science finally seems to be admitting that the Warburg Effect is a cause of cancer and not just a result/symptom/sign. The study goes on to discuss how...