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glucose

  1. haidut

    Vitamin B1 as a potential treatment for Alzheimer's Disease (AD)

    After decades of denial that AD is a metabolic condition, Big Pharma and Big Govt, are silently doing an 180-degree turn by secretly funding university clinical trials for metabolic interventions in that disease. The study below will evaluate the effects of benfotiamine - a lipophilic analog of...
  2. haidut

    Niacinamide increases ATP/NAD, lower glucose/cortisol in humans

    A great new study demonstrating for the first time in a human experiment what hundreds of animal studies had suggested in the past. Namely, that niacinamide can serve as a reliable precursor to NAD+ and by raising the NAD/NADH ratio results in improved glucose metabolism and higher ATP levels...
  3. Androsclerosis

    Anabolism all the time = more dreams. Why?

    Sincer started eating 500g+ carbs a day, a meal every 2 hours I started sleeping way deeper but at the same time I always have vivid dreams. I don't wake up tired but I would like to know why it happens. I remember when I was not peating, dreams were very rare. I think that my mind was on low...
  4. A

    Glucose as a Major Antioxidant: When, What for and Why It Fails?

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070274 Abstract A human organism depends on stable glucose blood levels in order to maintain its metabolic needs. Glucose is considered to be the most important energy source, and glycolysis is postulated as a backbone pathway. However, when the...
  5. haidut

    Epilepsy/seizures caused by energetic deficit leading to calcium overload

    Yet another study demonstrating that not only is a chronic, "incurable" disease of unknown origin treatable but that its main cause is energetic/metabolic and linked to impaired glucose metabolism. Specifically, the study demonstrated that impaired pyruvate transport into the mitochondria is...
  6. haidut

    Muscles starve/waste in the absence of vitamin D

    As turns out, yet again, vitamin D is far from being the simple "bone vitamin" as most TV/online commercials would have us believe. It is actually a (seco)steroid and has already been implicated in a host of metabolic and immune process affecting virtually every disease. Recently, I posted a few...
  7. haidut

    Human study - vitamin B1 safe & effective for preventing & treating Alzheimer Disease (AD)

    A remarkable study, that for some reason is not being covered by mainstream media. Considering 99% of the clinical trials for AD since 2000 have completely failed, this study should be front-page news for most mainstream outlets. I suspect mainstream media, being literally owned by the same...
  8. Hans

    The biggest missing links to optimal brain function – part 1

    What inspired me to write this article is overall reductionism when it comes to mental function. Far too many people want to focus on specific neurotransmitters and blame certain ones for certain conditions (e.g. low dopamine in anhedonia), but health as a whole started to deteriorate first, and...
  9. haidut

    Glucose + vitamin B3 combo synergistic for treating mitochondrial disease

    A very interesting study, which demonstrates the unique synergy between glucose and vitamin B3 in treating deficiencies of function in Complex I & II of the electron transport chain (ETC). Deficiencies on those metabolic steps are the most common causes for the wide varieties of debilitating...
  10. haidut

    DHT better (and safer) than testosterone for improving blood pressure, insulin levels

    A great human study on the beneficial effects of androgens for a variety of metabolic biomarkers associated with insulin resistance and diabetes II. The only gripe I have with this study is that they claim it was conducted with "healthy" men when in reality all men had low plasma total...
  11. haidut

    Blocking PUFA/prostaglandins restores metabolism and reverses brain aging

    The bad news for PUFA has been accumulating for decades, yet public health authorities continue to claim that type of fat is "essential". Whatever indirect admissions of the pathological role of PUFA in both chronic and acute/infectious diseases is given to the public, is usually confined to the...
  12. LLight

    The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201164/
  13. haidut

    Low energy production (glucose metabolism) may cause andropause

    As many of my readers know, aging men can also experience the equivalent of menopause and doctors informally call that state "andropause". Its official name is age-related hypogonadism and most of that hypogonadism is of the "secondary" type - i.e. the gonads appears to be in fine shape but for...
  14. haidut

    Forcing The Heart To Burn Glucose Instead Of Fat May Cure Heart Failure

    One of the blockbuster studies I have seen over the last 12 months. It reads as if written by Peat himself and discusses tissue regeneration, Randle cycle, dietary control of metabolism, etc. AFAIK this is the first study brave enough to demonstrate that simply switching fuel types in an...
  15. haidut

    Glucose Is Anabolic For Thymus, Opposes Catabolic Effects Of Cortisol

    As most of my readers know, cortisol is a highly catabolic steroid and one of the main agents (estrogen being another) responsible for thymus atrophy with age. These catabolic effects of cortisol can be blocked by progesterone, DHEA, pregnenolone, and even DHT (but not by testosterone). The...
  16. haidut

    Down Syndrome (DS) Cognitive Handicap Is Due To (cellular) Stress, May Be Reversible

    If there is any disease that is currently considered incurable even in principles, it likely comes from the group of inherited/genetic disorders. Perhaps the most well-known one, due to rapidly rising incidence and thus publicity, is DS. Perhaps its most disabling aspect of DS is the cognitive...
  17. haidut

    Mitochondrial Damage And Fatty Acid Buildup, Not Glucose, May Drive Diabetes

    Finally some common sense is coming out of mainstream medicine. The study below demonstrates that it is the buildup of fatty acid metabolites and mitochondrial damage that drives the chronic inflammation now known to be a major causative factor for diabetes II (T2DM), as well as virtually all...
  18. haidut

    MS Tied To Glucose Deficiency Due To Endotoxin And Fat, Extra Glucose May Treat It

    Just a few days ago I posted the groundbreaking study on metabolic derangement in ALS - i.e. it is a diseased characterized by increased FAO, which wastes glucose. Simply increasing dietary glucose was able to greatly restrain the pathology...
  19. haidut

    ALS Tied To Increased Fat Oxidation (FAO), Increasing Glucose May Treat It

    I made a few posts in the past about ALS characterized by adrenal hyperactivity and suppressed gonadal function, as well as mitochondrial dysfunction and copper deficiency. Also, non-familial ALS is known to occurs 4-5 times more often in active/retired elite athletes. All of these findings...
  20. ecstatichamster

    Inhaled Sugar May Lower Inflammation

    Is sugar the key to treating lung problems? The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation So type 2 immunity is the characterization of “allergies” Type 2 immunity in tissue repair and fibrosis Type 2 immunity is characterized by the...
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