glucocorticoid

  1. haidut

    Cortisol And Serotonin Are Causative Agents In (male) Liver Cancer

    The role of serotonin in all cancers of the billiary and GI tracts was well-known in the first half of the 20th century. The term carcinoid syndrome was used to describe the spectrum of such cancers and it was widely acknowledged that most of the patients died as a result of the fibrosis that...
    • haidut
    • Thread
    • causative cortisol glucocorticoid liver cancer males serotonin ssri
    • Replies: 4
    • Forum: Scientific Studies
  2. haidut

    Vitamin D Restores Sensitivity To Cortisol

    The so-called "glucocorticoid resistance" is thought be behind a number of degenerative conditions including diabetes, depression, schizophrenia, chronic inflammation, autoimmune conditions, etc. The condition, similar to insulin resistance, is characterized by elevated serum cortisol levels and...
    • haidut
    • Thread
    • calcitriol cholecalciferol cortisol glucocorticoid inflammation resistance sensitivity vitamin d
    • Replies: 18
    • Forum: Scientific Studies
  3. haidut

    The Anti-cortisol Mechanism Of Progesterone

    I just posted the thread on the anti-cortisol mechanism of pregnenolone. The Anti-cortisol Mechanism Of Pregnenolone As I mentioned in that thread, the Peat has been saying that both pregnenolone and progsterone have anti-cortisol effects, however people have been questioning those statements...
    • haidut
    • Thread
    • acceleration antagonist binding cortisol dissociation glucocorticoid progesterone receptor
    • Replies: 26
    • Forum: Scientific Studies
  4. haidut

    The Anti-cortisol Mechanism Of Pregnenolone

    One of the recurring arguments on this forum is whether pregnenolone and progesterone (being technically precursor to the glucocorticoids) raise or lower cortisol levels, and whether they have effects opposing or promoting those of the glucocorticoids. The argument advanced by a few people here...
    • haidut
    • Thread
    • antagonist cell cortisol glucocorticoid nucleus pregnenolone receptor translocation
    • Replies: 12
    • Forum: Scientific Studies
  5. haidut

    Stress Leads To Lower Dopamine And More Drinking

    The study was really on alcohol consumption what affects it. It has been known since the 1960s that people drink more when under stress but to this day mainstream medicine denies that there is a causative link between stress and substance abuse. I posted a few studies showing that "addicts" have...
    • haidut
    • Thread
    • addiction alcohol alcoholism cortisol crh dopamine drinking ethanol gaba glucocorticoid pregnenolone
    • Replies: 64
    • Forum: Scientific Studies
  6. haidut

    DHT Reduces Glucocorticoid Effects

    I mentioned this on one of the Danny Roddy shows, but wanted to post this study here as many people have been asking me for references over email. In addition to reducing glucocorticoid effects, DHT is also an estrogen "receptor" antagonist as I posted in another thread. DHT Is Estrogen...
  7. J

    Glucocorticoids Cause Brain Damage

    For the last few years, studies on the use of glucocorticoids ( prednisone, dexamethasone,ect) resulted in a smaller hippocampus and prefrontal cortex. Causing memory loss, attention loss and lower concentration. This study shows that Prednisone can actually reduce brain weight and decrease...
  8. haidut

    Carnitine Is A Glucocorticoid Agonist, Acts Like Cortisol

    Most people on the forum know of Ray's views on carnitine due to the fact that it stimulates fat oxidation. The drug mildronate, which Ray has written about, is a carnitine antagonist and is used as a performance enhancing drug by many athletes. This study shows that there is another good reason...
  9. haidut

    Vitamin B6 (P5P) Is A Glucocorticoid (cortisol) Antagonist

    The studies go back to 1960s and 1970s but when I read them I was surprised to find that the activated form of vitamin B6 called pyridoxal-5-phosphate (what we also use for our Energin supplement) is a glucocorticoid "receptor" antagonist. Some of the in vivo studies referenced in the studies...
    • haidut
    • Thread
    • antagonist cortisol glucocorticoid p5p study vitamin b6
    • Replies: 10
    • Forum: Scientific Studies
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