glucocorticoid receptor

  1. haidut

    Vitamin D prevents cortisol-induced depression and...inflammation

    A great study for a number of reasons. First, it discussed openly that in animal research circles cortisol administration is considered an official and reliable method of causing major depression. As the article states, for some reason human medical circles have been unwilling to accept the...
  2. haidut

    Cortisol Drives Triple-negative Breast Cancer, Androgens (DHT) Are Therapeutic

    Another confirmation of a hypothesis made more than 100 years ago - i.e. all cancers are hormonally sensitive and to speak of a steroid-negative cancer is nonsense. If all cancers are driven by at least one steroid then it would make sense to discover what that steroid is and develop therapeutic...
  3. haidut

    PUFA Enhance Glucocorticoid (cortisol) Signalling

    I posted some studied in the past on the estrogenic and pro-cortisol effects of PUFA, as well as the pro-androgen effects of SFA. One of those studies showed that PUFA increases cortisol synthesis even in the absence of ACTH, which suggests that they may have pituitary hormonal-like effects...
  4. haidut

    6-keto P4 - Liquid 6-ketoprogesterone For Lab/R&D

    As many forum users know, preventing tissue destruction as a result of hypothyroidism and stress is one of the main topics the pro-metabolic approach focuses on. While tissue catabolism can be drive by a number of mediators working in tandem, the main catabolic steriod in the human organism is...
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