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glaucoma

  1. haidut

    Niacinamide + pyruvate may treat glaucoma (human study)

    Some excellent results from a human clinical trial. Namely, a combination of 3g niacinamide and 3g (calcium) pyruvate daily demonstrated significant therapeutic effect in patients with already established glaucoma. I can't access to actual study link on JAMA, but I suspect the mechanism of...
  2. haidut

    Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide

    About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH ratio in glaucoma patients. That study used niacinamide (NAM) and suggested that the "irreversible" changes in eye structure seen in glaucoma patients are in fact nothing more...
  3. charlie

    Vitamin B3 (Niacinamide) Shows Promise For Glaucoma Patients In Clinical Trial

    "Results of the trial, led by Professor Jonathan Crowston and Dr. Flora Hui at the Center for Eye Research Australia, are published today in Clinical and Experimental Ophthalmology. They show "significant improvement" in the visual function of glaucoma patients who received a daily high dose of...
  4. P

    Vitamin B3 Modulates Mitochondrial Vulnerability And Prevents Glaucoma In Aged Mice

    Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. - PubMed - NCBI Glaucomas are neurodegenerative diseases that cause vision loss, especially in the elderly. The mechanisms initiating glaucoma and driving neuronal vulnerability during normal aging are...
  5. P

    Vitamin B3/NAD Fully Prevents The Development Of Glaucoma In Mice And Halts Its Progression If Alrea

    Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice | Science "Oral administration of the NAD+ precursor nicotinamide (vitamin B3), and/or gene therapy (driving expression of Nmnat1, a key NAD+-producing enzyme), was protective both prophylactically and as an...
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