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Gut. 2005 Jul; 54(7): 966–971.
Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis
W Stremmel,1 U Merle,1 A Zahn,1 F Autschbach,2 U Hinz,3 and R Ehehalt1
Author information Article notes...
The alcohol case is clear and it is well known that it damages the mucosa. The drug used to induce damage was ibuprofen, but I don't see why the results and conclusions would not translate to aspirin as well, thus making an even stronger case for combining aspirin with caffeine. Effective human...
If there was any doubt that serotonin and histamine are not good for you hen chronically elevated, here is an older study showing both substances producing gastric lesions in rats. Look in the section "Production of gastric lesions" for details.