1. Mauritio

    MCTs and Coconut Milk increase bile excretion and activate FXR

    (*Coconut milk in the headline) These two study show that MCTs and Coconut milk increase bile acid excretion and inhibit re-absorption. It might very well be that the MCTs in coconut milk are responsbile for that effect, since it is about 50% lauric acid. I think that is an important point...
  2. Mauritio

    Activating FXR decreases PUFA in the liver

    Very interesting study showing that activating the Farnesoid X Receptor results in lower levels of MUFA and PUFA in the liver. (Farnesoid X receptor - Wikipedia) Lowers levels of MUFA are brought on by downregulating genes like SCD1. "Elevated expression levels of SCD1 is found to be...
  3. L

    Various Synthetic FXR-Agonists With Interesting Capacities

    Compiling of publications on said substances - and an attepmt to decipher natural or freely available similar substances and mimetics
  4. haidut

    Androsterone Is A Potent Agonist / Activator Of The Farnesoid X Receptor (FXR)

    The so-called Farnesoid X Receptor (FXR) is a very interesting nuclear receptor inside the cell. It has a multitude of functions, but one of the main functions includes sensing and controlling the levels and synthesis of bile acids. As I mentioned in a few other posts, nuclear receptors...
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