1. C

    Is Propranolol Unique Or Can Other Beta Blockers Be Used For PTSD, Bad Memories etc...?

    There are lots of potential applications for this lipophilic and non-selective beta blocker. Can any other beta blockers be used or is it special? Metoprolol seems to be similar (although more selective and less lipophilic). Could it probably be substituted and work as well?
  2. haidut

    Serotonin (5-HT) drives fear and conditions such as anxiety/PTSD

    Conversely, blocking 5-HT or lowering its synthesis can probably cure most fear-based conditions such as generalized anxiety disorder (GAD), PTSD, psychotic conditions (e.g. schizophrenia), etc. At least, those are the findings of the study below, which demonstrated that animals completely...
  3. haidut

    Serotonin enhances learning from punishment, reduces learning from reward

    Research as early as the 1960s firmly established that there is nothing "happy" when it comes to serotonin (5-HT). Namely, elevated 5-HT levels were found in many chronic diseases and especially clinical depression. It took more than 7 decades for medicine to finally start admitting that 5-HT is...
  4. Hans

    The only hormone you need to crush fear

    https://men-elite.com/2021/11/08/the-only-hormone-you-need-to-crush-fear/ Have you used it before? And if so, how did it make you feel?
  5. Hans

    Tired of feeling anxious and submissive? Here’s how to fix it

    It all comes down to energy production. How effectively your cells can produce energy. https://men-elite.com/2021/08/16/tired-of-feeling-anxious-and-submissive-heres-how-to-fix-it/ I'd also like to hear from you. What has worked great for you to optimize both your energy and reduce anxiety?
  6. haidut

    Serotonin (and SSRI drugs) can cause anxiety and PTSD

    Yet another great study exposing just how much of a "happy hormone" serotonin really is. As usual, the popular press article does everything possible to avoid pointing the finger at serotonin and even engages in misdirection. For example, it says that SERT is the main target of drugs like...
  7. MetabolicTrash

    Chronic Pain Relieved Greatly By Benadryl/diphenhydramine & Nightmares (story-time)?

    I'm including details here that I've never told anyone/written that much about to my knowledge, but all of it does not need to be read if you're not used to my extremely long, often (arguably) strange posts I make here. So I was going to post here about it (the pain), but figured it would be a...
  8. md_a

    How Chronic Fear Results In Hypoxia In Tissues And Cancer In Humans Through Bohr Effect

    How Chronic Fear Results In Hypoxia in Tissues and Cancer in Humans through Bohr Effect Professor Sir Sorush Niknamian; Dr. Somayeh Zaminpira Fear is a number of chain reactions in the brain that occurs when one encounters a potentially harmful stimulus. The amygdala is the part of the brain...
  9. haidut

    Blocking Stress (adrenaline) Just Once Cures PTSD And Maybe Any Mental Disorder

    This is a remarkable study, which once again implicates extreme stress in the pathology of mental health disorders, specifically anxiety and PTSD. Just a few days ago I posted a study showing a high cortisol (C) / testosterone (T) ratio is likely causative in PTSD. People with high C/T ratio...
  10. haidut

    Pollution (and Resulting Anxiety) Predicts Violence And Unethical Behavior

    For those of you who have read the book Freakonomics, you probably remember the chapter discussing the drop in violent crime in the US during the late 80s and early 90s. The authors made the claim that neither better law enforcement, nor social programs were responsible for that drop. Rather...
  11. P

    Blocking Human Fear Memory With The Matrix Metalloproteinase Inhibitor Doxycycline

    Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline D R Bach , A Tzovara & J Vunder Molecular Psychiatry doi:10.1038/mp.2017.65 Download Citation Neuroscience Received: 05...
  12. haidut

    The Darker Side Of Serotonin Finally Exposed - It Increases Anxiety And Suicide

    I guess the fact that such studies are finally starting to come out is a good sign. I don't think this will hurt Prozac sales in any way, but at least now doctors may start to discuss with patients the potential dangers of SSRI, which up until last year were considered to be pure myth. It still...
  13. P

    Methylene Blue Facilitates The Extinction Of Fear In An Animal Model Of Susceptibility To Learned He

    Methylene blue facilitates the extinction of fear in an animal model of susceptibility to learned helplessness. - PubMed - NCBI Abstract The objectives were to (1) extend previous findings on fear extinction deficits in male congenitally helpless rats (a model for susceptibility to learned...
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