Due to excessive bot signups along with nefarious actors we are limiting forum registration. Keep checking back for the register link to appear. Please do not send emails or have someone post to the forum asking for a signup link. Until the current climate changes we do not see a change of this policy. To join the forum you must have a compelling reason. Letting us know what skills/knowledge you will bring to the community along with the intent of your stay here will help in getting you approved.
Conversely, blocking 5-HT or lowering its synthesis can probably cure most fear-based conditions such as generalized anxiety disorder (GAD), PTSD, psychotic conditions (e.g. schizophrenia), etc. At least, those are the findings of the study below, which demonstrated that animals completely...
Research as early as the 1960s firmly established that there is nothing "happy" when it comes to serotonin (5-HT). Namely, elevated 5-HT levels were found in many chronic diseases and especially clinical depression. It took more than 7 decades for medicine to finally start admitting that 5-HT is...
It all comes down to energy production. How effectively your cells can produce energy.
https://men-elite.com/2021/08/16/tired-of-feeling-anxious-and-submissive-heres-how-to-fix-it/
I'd also like to hear from you. What has worked great for you to optimize both your energy and reduce anxiety?
Yet another great study exposing just how much of a "happy hormone" serotonin really is. As usual, the popular press article does everything possible to avoid pointing the finger at serotonin and even engages in misdirection. For example, it says that SERT is the main target of drugs like...
I'm including details here that I've never told anyone/written that much about to my knowledge, but all of it does not need to be read if you're not used to my extremely long, often (arguably) strange posts I make here.
So I was going to post here about it (the pain), but figured it would be a...
How Chronic Fear Results In Hypoxia in Tissues and Cancer in Humans through Bohr Effect
Professor Sir Sorush Niknamian; Dr. Somayeh Zaminpira
Fear is a number of chain reactions in the brain that occurs when one encounters a potentially harmful stimulus. The amygdala is the part of the brain...
This is a remarkable study, which once again implicates extreme stress in the pathology of mental health disorders, specifically anxiety and PTSD. Just a few days ago I posted a study showing a high cortisol (C) / testosterone (T) ratio is likely causative in PTSD. People with high C/T ratio...
For those of you who have read the book Freakonomics, you probably remember the chapter discussing the drop in violent crime in the US during the late 80s and early 90s. The authors made the claim that neither better law enforcement, nor social programs were responsible for that drop. Rather...
Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline
Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline
D R Bach
, A Tzovara
& J Vunder
Molecular Psychiatry
doi:10.1038/mp.2017.65
Download Citation
Neuroscience
Received:
05...
I guess the fact that such studies are finally starting to come out is a good sign. I don't think this will hurt Prozac sales in any way, but at least now doctors may start to discuss with patients the potential dangers of SSRI, which up until last year were considered to be pure myth. It still...
Methylene blue facilitates the extinction of fear in an animal model of susceptibility to learned helplessness. - PubMed - NCBI
Abstract
The objectives were to (1) extend previous findings on fear extinction deficits in male congenitally helpless rats (a model for susceptibility to learned...