fatty acid

One of the core issues in modern endocrinology is the relatively weak correlation between serum levels of steroids and the overall activity in the organism associated with a particular steroid. For example, post-menopausal women have very low levels of estradiol yet very high whole-body...

Finally some common sense is coming out of mainstream medicine. The study below demonstrates that it is the buildup of fatty acid metabolites and mitochondrial damage that drives the chronic inflammation now known to be a major causative factor for diabetes II (T2DM), as well as virtually all...

I posted some studied in the past on the estrogenic and pro-cortisol effects of PUFA, as well as the pro-androgen effects of SFA. One of those studies showed that PUFA increases cortisol synthesis even in the absence of ACTH, which suggests that they may have pituitary hormonal-like effects...

Altering fatty acid availability does not impair prolonged, continuous running to fatigue: evidence for carbohydrate dependence.

This is the original study that postulated the existence of the Randle Cycle. I strongly recommend that everyone reads it as it will likely dispell whatever doubts you may have had about Peat and his ideas. I have posted many other studies that directly support the role of the Randle Cycle in...

Hi folks! I have some strong points against some of Rays ideas: So all started because my blood lipid levels have gone bad from being spot on average before I started "peating". LDL is high now. I was looking around once more and found quite shocking information. It is quite obvious and...

Comparative toxicity of fatty acids on a macrophage cell line (J774) http://www.clinsci.org/cs/111/0307/1110307.pdf Everyday I get more and more impressed by how accurate most claims by Ray Peat are..