ethanol

  1. Mauritio

    Alcohol only causes fatty liver when consumed with PUFA not with SFAs

    In this study they authors studied how the intake of saturated and unsaturated fats affect the effect of alchohol on the body. They looked at he usual things that alcohol consumption causes in the body (necrosis, fatty liver and inflammation), while also feeding the animals fish oil, corn oil...
    • Mauritio
    • Thread
    • alcohol ethanol fatty liver lipid peroxidation liver liver damage mct oil pufa saturated fat sfa
    • Replies: 9
    • Forum: Scientific Studies
  2. haidut

    Niacinamide fully reverses endotoxemia and leaky gut (from ethanol)

    The study below is a true gem due to both its broadness of impact, as well as the ease and low-cost of the therapeutic intervention it studied. Chronic endotoxemia, a cause and a result of increased gut permeability (aka "leaky gut") is now known to be a major cause of virtually all chronic...
    • haidut
    • Thread
    • alcohol atp endotoxin ethanol leaky gut lps nad niacinamide nicotinamide
    • Replies: 21
    • Forum: Scientific Studies
  3. haidut

    Supplementation With (long Chain) Saturated Fats Protects Liver From Alcohol

    As many of my readers already know, there are a number of human studies, going back to at least the 1960s, demonstrating that supplementation with saturated fats (SFA) protects the liver from damage induced by alcohol. I fact, supplementation with SFA not only prevents alcohol-induced liver...
    • haidut
    • Thread
    • alcohol damage dysbiosis dysfunction endotoxin ethanol fibrosis lcsfa liver lps protective reverse saturated fat sfa sibo tlr4 treatment
    • Replies: 1
    • Forum: Scientific Studies
  4. haidut

    PUFA Increases Alcohol Damage By Increasing Cell Fluidity; SFA Are Protective

    Peat has written a number of times on the synergies of PUFA with ethanol and endotoxin on causing liver and systemic damage. In one of his articles he opined that in the absense of PUFA/iron ethanol would likely not cause much harm. He also wrote about the protective effects of saturated fats...
    • haidut
    • Thread
    • alcohol cell damage ethanol fluidity membrane permeability promote protective pufa saturated fat sfa
    • Replies: 5
    • Forum: Scientific Studies
  5. haidut

    Alcohol Mostly Benign For The Liver, Causing Injury Requires Endotoxin (LPS)

    Peat wrote in one of his articles that alcohol is getting a bad reputation for causing all sorts of liver disease and even liver cancer, but alcohol by itself is fairly neutral for the liver and that the role of PUFA, iron and endotoxin is being neglected by mainstream medicine. The study below...
    • haidut
    • Thread
    • alcohol endotoxin ethanol fatty liver fibrosis inflammation liver disease lps nafld
    • Replies: 52
    • Forum: Scientific Studies
  6. haidut

    Thyroid May Treat Fetal Alcohol Syndrome (FAS)

    The so-called fetal alcohol syndrome has been on the rise over the last 2 decades and its symptoms largely overlap with the "adult" alcohol syndrome or at least the behavioral parts of it. Broda Barnes once wrote that he never treated an alcoholic who was not also hypothyroid and that he also...
    • haidut
    • Thread
    • alcohol ethanol fetal alcohol syndrome hypothyroidism pregnancy reverse thyroid thyroxine
    • Replies: 1
    • Forum: Scientific Studies
  7. haidut

    Safety Of Long-term Use Of DMSO As A Solvent

    I wanted to post this even though it won't change the mind of DMSO opponents. The topic of DMSO safety has come up multiple times among scientists using it as a solvent for delivery of chemicals in vivo studies and so I did some digging and found some interesting data point. First, DMSO used in...
    • haidut
    • Thread
    • acetone animals chronic dmso ethanol liver peg pg protective safety solvent toxicity
    • Replies: 136
    • Forum: Scientific Studies
  8. haidut

    Stress Leads To Lower Dopamine And More Drinking

    The study was really on alcohol consumption what affects it. It has been known since the 1960s that people drink more when under stress but to this day mainstream medicine denies that there is a causative link between stress and substance abuse. I posted a few studies showing that "addicts" have...
    • haidut
    • Thread
    • addiction alcohol alcoholism cortisol crh dopamine drinking ethanol gaba glucocorticoid pregnenolone
    • Replies: 64
    • Forum: Scientific Studies
  9. haidut

    Recovering Steroidogenesis Inhibited By Alcohol And Drugs

    As many of you know, drugs like Finasteride are really bad not only because they cause a variety of CNS effects as a result of inhibiting 5-AR, but also because they systemically inhibit the entire steroid synthesis cascade. Toxins and alcohol do the same and currently there is no approved...
  10. haidut

    Ethanol Intoxication / Sedation Caused By Adrenaline

    I came across this during research into increasing dopaminergic activity without also increasing adrenergic tone. Apparently, the feeling of getting drunk as well as the sedation produced by alcohol is due to the increased synthesis of adrenaline (epinephrine). Blocking that synthesis by...
    • haidut
    • Thread
    • adrenaline alcohol epinephrine ethanol intoxication pnmt sedation
    • Replies: 3
    • Forum: Scientific Studies
  11. S

    No Liver Injury After Alcohol In Germ-Free Mice

    Comparing the effects of acute alcohol consumption in germ-free and conventional mice: the role of the gut microbiota Ethanol increased intestinal bacteria :cool and "high fiber diet" reduced the injury.
  12. Hugh Johnson

    Effects Of Chronic Ethanol Treatment On Lipid Composition And Prostaglandins In Rats Fed Essential F

    http://www.ncbi.nlm.nih.gov/pubmed/6428253 The data are consistent with an increased utilization of EFA during chronic ethanol intoxication leading to a depletion of PG precursor stores in some but not all organs. Time to supplement with some alcohol.
  13. Hugh Johnson

    The Effect Of Ethanol On One-carbon Metabolism: Increased Methionine Catabolism And Lipotrope Methyl

    http://onlinelibrary.wiley.com/doi/10.1 ... 3/abstract
  14. haidut

    Chronic Ethanol Consumption Same As Chemical Castration

    As Ray said, alcohol is estrogenic and should be consumed in moderation and preferably using clear spirits. The fact that castration and chronic alcohol consumption did not have synergistic effects suggests that alcohol consumption alone matched the effect of castration. Effects of chronic...
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