estrogen

  1. A

    Are White Button Mushrooms Estrogenic or Anti-Estrogenic?

    Inhibiting aromatase activity make it seem like they are anti-estrogenic but they also compete with estrogen for binding to estrogen receptors. Is their agonist efficacy lower than estrogen or in fact higher?
  2. haidut

    An estrogen antagonist treats many cancers, including triple-negative breast cancer

    Just a portion of the title is already paradoxical, according to mainstream medical dogma. Namely, how can an estrogen antagonist treat triple-negative breast cancer that is supposedly fully immune to any hormonal effects!? Well, maybe the whole idea of hormonal "receptors" as the only mechanism...
  3. haidut

    Higher progesterone, lower estrogen makes women more generous

    It looks like the beneficial effects if progesterone and harmful effects of estrogen are not limited to health. The study below found a women become much more generous in terms of buying drinks or gifts for their peers during the luteal phase, when progesterone is elevated and estrogen is low...
  4. haidut

    DHT blocks, androgen antagonists promote breast cancer

    The first claim of the title is already well-known to my readers and to clinical practice. DHT was clinically used back in the middle of the 20th century as a treatment for breast cancer, and the synthetic androgen Drostanolone (Masteron), which still retains its approval by FDA for breast...
  5. Gûs80

    Could aromatase inhibitors be useful in autoimmune diseases?

    Dr Ray Peat mentions in some articles that the cause of autoimmune diseases is high estrogen. Considering this, has anyone seen benefits from using a pharmaceutical aromatase inhibitor? I have a positive ANA marker for Lupus/Sjogren's, and even though it's low, I have several of the symptoms of...
  6. haidut

    Stearic acid (SA) is an estrogen receptor antagonist

    Over the last year or so I stumbled upon a few studies claiming both SA (C18:0) and its methyl ester are capable of binding the estrogen receptors (ER) and modulate their transcription effects. However, those studies did not evaluate if SA acted as an agonist or antagonist on those receptors...
  7. mantq

    Do aromatase inhibitors cause hair loss?

    Do aromatase inhibitors cause hair loss?
  8. MetabolicTrash

    Muscle & Growth Overall = (mostly) Unsaturated; Estrogenic? Is this why some people have bigger muscles or bigger bones; others smaller/less mass?

    Obviously it's more complicated than that to a degree, but I got to reading this old thread by @haidut on saturatedness or unsaturedness: https://raypeatforum.com/community/threads/unsaturation-estrogenic-saturation-androgenic.13162/#post-180467 Here is the study he referenced: Oestrogenic...
  9. tastyfood

    Which daily habits that you consider estrogenic go unnoticed?

    I am trying to keep my estrogen lower by paying more attention to things that I do on a daily basis that could have an estrogenic effect. Two examples I can share: - Using toilet paper for cleaning the buttocks as well as blowing the nose. - Washing the skin with soap excessively. These...
  10. haidut

    Estrogen may cause/exacerbate reflux disease (GERD)

    A very interesting study, which once again corroborates the hypothesis that there is no chronic condition, which is not either caused or heavily influenced by steroids. Among the conditions medicine considers not to be linked to hormone imbalances is the extremely common "reflux disease"...
  11. haidut

    Alzheimer's Severity Tied to Longer Estrogen Exposure in Women

    A neat study, which somehow managed to slip through my "radar" when it was first published the middle of last (2021) year. The study is pretty straighforward in its claim that longer exposure to endogenous estrogen was associated with exacerbated/higher biomarkers of Alzheimer disease (AD), as...
  12. haidut

    Estrogen promotes, progesterone inhibits drug (cocaine) abuse

    An interesting study, which not only exposes yet another negative side of estrogen but also demonstrates the opposing actions estrogen and progesterone have on the brain. The former is excitatory (by activating the glutamate system and inhibiting the GABA system) while the latter does the exact...
  13. A

    How fingers could point to a link between low testosterone and COVID hospitalizations

    https://www.swansea.ac.uk/press-office/news-events/news/2022/03/how-fingers-could-point-to-a-link-between-low-testosterone-and-covid-hospitalizations.php Could the length of a person’s fingers provide a clue to how ill they might get after contracting Covid-19? It is widely recognised that a...
  14. Drareg

    Glow Fish: A New Biosensor to Detect How Environmental Estrogens Affect Tissues

    Interesting study, this a genetically engineered organism, you can buy them, its used to subtly introduce the public to genetic engineering. PMC3404679 Chemicals that mimic natural estrogens have well-documented effects on the reproductive systems of vertebrates, typically acting as endocrine...
  15. tastyfood

    What benefits have you seen from just using water instead of toiler paper after bowel movements?

    I started experimenting with just using water to wash after bowel movements. After some of the threads shared on this forum about the presence of possibly estrogenic substances in toilet paper, I decided to stop using it for a while. Unfortunately, I don't experience ghost-like stools, and I...
  16. D

    Menopausal issuse

    This question is mainly directed to menopausal/postmenopausal women. I am asking for my mum. Since she hit menopause a few years ago she has some rough/dry/brittle epithelium/lining in her vagina, that does easily tear making intercourse a painful experience. Her gynecologist perscribed her...
  17. tastyfood

    Is there any possibility that high prolactin in blood mean low estrogen in tissues?

    There are arguments that explain that certain estrogenic high values in blood would mean low levels in tissues: Estradiol and estrone are two that come to mind. Is there any possibility that a high result for prolactin in blood means low estrogen in tissues, or is high prolactin ALWAYS related...
  18. tastyfood

    I'm desperate, prolactin is out of control despite taking anti-prolactin substances

    I've been dealing with high prolactin for the last 6 months and the result I got from yesterday is terrifying. 28.2 ng/mL (reference range 4.0-15.2). This is a jump from 16.3 from a month and half ago! I can provide more info about other results, but they are all in range. My TSH is suppressed...
  19. Yonebayashian

    Crashing Estrogen As a Male; How To and What To Expect

    After reading people on this forum talking about this, I'm wondering if it would be worthwhile for myself as a male to try and crash my estrogen. Would the results be positive? What aromatase inhibitors should I take if I wanted to do this?
  20. haidut

    Estrogen associated with arterial stiffness in women

    Blood pressure rises with age, and most people over the age of 50 are on some type of blood pressure controlling medication. It is well-known that blood vessels calcify/stiffen with age and that such stiffness is what leads to increased blood pressure - i.e. the inability of vessels to...
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