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energy

  1. B

    This magic morning.

    So, I awakened at 4am. Felt like sitting with my laptop to read, but instead began my morning exercise/stretch routine. It's upper body day so a little different from lower body day. I grudgingly went into the library where I have two yoga mats over the rug with a rug pad. Underneath is our...
    • Birdie
    • Thread
    • carrot salad coffee milk energy sleep
    • Replies: 8
    • Forum: Logs
  2. haidut

    BOMBSHELL: Serotonin High in Depression, Not a "Happy" Chemical, Lowers Energy, Depression Self-Resolves

    When I first saw the article pop up in my feed, I could hardly believe my eyes that a mainstream mouthpiece of Big Pharma will publish such frank admission of psychiatry's utter failure - i.e. the claims in regards to serotonin (5-HT), its role in mental illness, and even its social "label". In...
    • haidut
    • Thread
    • 5-ht depression energy metabolism oxphos serotonin ssri suicide
    • Replies: 26
    • Forum: Scientific Studies
  3. haidut

    Muscles starve/waste in the absence of vitamin D

    As turns out, yet again, vitamin D is far from being the simple "bone vitamin" as most TV/online commercials would have us believe. It is actually a (seco)steroid and has already been implicated in a host of metabolic and immune process affecting virtually every disease. Recently, I posted a few...
    • haidut
    • Thread
    • cholecalciferol energy glucose glycogen muscle sarcopenia vitamin d wasting
    • Replies: 3
    • Forum: Scientific Studies
  4. haidut

    Niacinamide + pyruvate may treat glaucoma (human study)

    Some excellent results from a human clinical trial. Namely, a combination of 3g niacinamide and 3g (calcium) pyruvate daily demonstrated significant therapeutic effect in patients with already established glaucoma. I can't access to actual study link on JAMA, but I suspect the mechanism of...
    • haidut
    • Thread
    • energy glaucoma niacinamide pyrucet pyruvate redox vitamin b3
    • Replies: 10
    • Forum: Scientific Studies
  5. RealNeat

    Peaty Energy Drink (no not Red Bull)

    It's not perfect, but it's one of the best I can find and it even has thiamine (nitrate form) which is not common in energy drinks. It unfortunately has citric acid and agave instead of cane sugar. But it's other components and herbs feel really good and I can regularly depend on it for a mood...
    • RealNeat
    • Thread
    • bvitamins drink energy gaba
    • Replies: 15
    • Forum: Diet
  6. haidut

    Vitamin B1 and/or biotin may treat Huntington Disease (HD)

    As some of my own studies with cancer recently demonstrated, vitamins are no laughing matter when it comes to their ability to treat very serious conditions. This seems to be especially true in regards to the B vitamins, which are required co-factors for most of the metabolic reactions inside...
    • haidut
    • Thread
    • atp biotin energy huntington metabolism thiamine vitamin b1 vitamin b7
    • Replies: 35
    • Forum: Scientific Studies
  7. haidut

    Aging is an energy deficiency problem, taking cardiolipin may reverse it

    Yet another study demonstrating that "aging" is nothing but a phenotype characterizing an organism with declining energy production. Since most of the cellular energy is produced in the mitochondria, another way of stating the same is that aging (and any specific disease for that matter) is a...
    • haidut
    • Thread
    • aging cardiolipin disease energy lifespan metabolism mitochondria oxphos
    • Replies: 8
    • Forum: Scientific Studies
  8. youngsinatra

    Does Coffee Inhibit B1 Absorption?

    I've read multiple times that compounds in coffee can inhibit thiamin absorption. I am wondering if it inhibits it completely or just partly? I like taking 200mg of thiamin HCL with my meals and I really love a good espresso or two after some meals. I am wondering if it has any real effect...
  9. haidut

    COVID-19 is an energy deficiency disease

    Yet another seemingly non-metabolic disease turns out to be nothing but energy deficiency in disguise. Apparently, the SARS-CoV-2 virus selectively disables so-called complex I of the electron transport chain (ETC), and as such the overall OXPHOS process. Such inhibition is known to reliably...
    • haidut
    • Thread
    • complex i covid-19 electron transport chain energy etc mitochondria oxphos sars-cov-2
    • Replies: 5
    • Forum: Scientific Studies
  10. haidut

    Mitochondrial dysfunction may be the cause of anemia

    Despite anemia being a pretty common condition, I still don't think medicine has a good idea what causes anemia (putting aside the more obvious reasons such as chronic bleeding and dietary iron deficiency). In one of the KMUD interviews Peat opined that in his opinion true iron deficiency...
  11. haidut

    Vitamin D deficiency impairs muscles by lowering energy production

    Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition...
    • haidut
    • Thread
    • cholecalciferol energy mitochondria muscle oxphos sarcopenia vitamin d vitamin d3
    • Replies: 2
    • Forum: Scientific Studies
  12. D

    All These Threads On Hair Loss Go Nowhere Because....

    ....because what we really need is feedback from those who HAVE their hair - a survey or study on their health, habits, diets, fathers/heredity, etc. How we go about doing that I don't know, but I could guess, there wouldn't be found anything markedly different about them then those who've lost...
    • DMF
    • Thread
    • energy epigenetics genetics hair loss progesterone
    • Replies: 19
    • Forum: Hair & Nails
  13. haidut

    Metabolic (energy) deficiency may be the cause of Parkinson Disease (PD)

    The dogma that PD is just a simple dopamine deficiency manifesting in genetically vulnerable individuals is quickly becoming untenable. It is well-known among clinicians that administering dopamine precursors such as L-Dopa, or selective dopamine agonists such as pramipexole has limited...
    • haidut
    • Thread
    • deficiency energy metabolism mitochondria parkinson pd ros
    • Replies: 25
    • Forum: Scientific Studies
  14. F

    My stack for testosterone, anxiety, inflammation and muscle growth: reasonable?

    Hi guys, I've assembled the following stack, in order to address a few goals: - creatine, shilajit, cordyceps, B complex (with niacinamide), vit E, vit K, vit D: testosterone, DHT, anxiety, energy, muscle growth - berberine: gut health, lowering overall inflammation (I have an autoimmune...
    • faxmulder
    • Thread
    • anxiolytic energy inflammation muscle gain testosterone
    • Replies: 61
    • Forum: Supplements
  15. Hans

    PUFAs, cardiolipin, ATP production and obesity

    As we all know, PUFAs are a metabolic toxin. One of the mechanisms how a high fat diet promotes obesity and metabolic syndrome is by remodeling cardiolipin. Cardiolipin is a unique mitochondrial phospholipid that contains 4 fatty acids. Its main goal is to stabilize the complexes of the electron...
    • Hans
    • Thread
    • atp cardiolipin electron transport chain energy pufas saturated fat
    • Replies: 6
    • Forum: Scientific Studies
  16. haidut

    Reduced pyruvate and/or increased lactate drive heart failure

    I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate in the pathogenesis of glaucoma. Just minutes later, another study popped up in my newsfeed. Namely, a study that demonstrates the exact same metabolic disturbances as the main drivers of...
    • haidut
    • Thread
    • energy heart failure lactate lactic acid metabolism oxphos pyruvate
    • Replies: 0
    • Forum: Scientific Studies
  17. haidut

    Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide

    About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH ratio in glaucoma patients. That study used niacinamide (NAM) and suggested that the "irreversible" changes in eye structure seen in glaucoma patients are in fact nothing more...
    • haidut
    • Thread
    • energy eye glaucoma niacinamide oxphos pyrucet pyruvate
    • Replies: 2
    • Forum: Scientific Studies
  18. haidut

    Low energy production (glucose metabolism) may cause andropause

    As many of my readers know, aging men can also experience the equivalent of menopause and doctors informally call that state "andropause". Its official name is age-related hypogonadism and most of that hypogonadism is of the "secondary" type - i.e. the gonads appears to be in fine shape but for...
    • haidut
    • Thread
    • aging andropause energy glucose hypogonadism metabolism steroidogenesis testosterone
    • Replies: 0
    • Forum: Scientific Studies
  19. haidut

    The Cure For Aging Might Be The Cure For Alzheimer’s

    Almost 25 years ago, Dr. Peat himself wrote a 2-article series in which he outlined arguments in favor of the hypothesis that aging and Alzheimer Disease (AD) are just examples of a more and less systemic sign respectively of declining energy production, and that curing one would lead to a cure...
    • haidut
    • Thread
    • aging alzheimer cure disease energy immortality metabolism
    • Replies: 3
    • Forum: Scientific Studies
  20. haidut

    Red Light Therapy For Parkinson Disease (PD) Begins Human Trials

    A few weeks ago, I posted about a human study demonstrating reversal of age-related vision decline by staring at a red light for just a few minutes a day. The mechanism of action proposed in that study had to do with improved mitochondrial function and energy production. Now, it seems another...
    • haidut
    • Thread
    • cytochrome c energy human metabolism mitochondria parkinson red light
    • Replies: 2
    • Forum: Scientific Studies
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