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The study below demonstrates yet again that there is hardly an aspect of human health that PUFA does not influence in a detrimental manner, even seemingly non-metabolic aspects such as bacterial infections. As it turns out, most bacteria express the enzyme family known as lipoxygenases (LOX) and...
Been on a very low PUFA and restricted diet (mostly carnivore, but experimented a lot with carbs, no fish) for almost 2 years.
I've had dry skin, especially on my knuckles for about 1 and a half years.
I had read to eat more fat and so I did. Lamb fat, beef fat, but the more fat I ate, the...
Another great study, and one of the few that dares point the finger at medicine's Holy Grail - the "essential fatty acids". As the study aptly says, high levels of PUFA in the blood and especially higher levels of linoleic acid predict subsequent development of acute lymphoblastic leukemia (ALL)...
A Fall in Plasma Free Fatty Acid (FFA) Level Activates the Hypothalamic-Pituitary-Adrenal Axis Independent of Plasma Glucose: Evidence for Brain Sensing of Circulating FFA
Endocrinology. 2012 Aug; 153(8): 3587–3592.
Published online 2012 Jun 1. doi: 10.1210/en.2012-1330
PMCID: PMC3404348...
I wanted to post this as it allows people who cannot tolerate coconut oil or other saturated fat orally to still inflluence their systemic SFA : PUFA balance. This study looked at the transdermal absorption of PUFA (safflower oil) and SFA (coconut oil) and found both to be rather well absorbed...
A human study and as such very relevant. The dose of DHEA used was high (200mg), but androgens derived from DHEA have the same (and even more potent) effects in much lower doses, so low-dose DHEA should have similar (if not even better) effect. Yet another indication that androgens are...