doxycycline

  1. P

    Doxycycline , intestinal health, hypertension

    Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats DOX decreased lactate-producing bacterial population and plasma lactate levels, improved gut barrier integrity, normalized endotoxemia, plasma noradrenaline levels...
  2. B

    Doxycycline Impairs Cardiac Mitochondrial and Contractile Function

    Mice treated with doxycycline showed mitochondrial complex I dysfunction, reduced OXPHOS capacity and impaired diastolic function. Doxycycline exacerbated diastolic dysfunction and reduced ejection fraction in a diabetes mouse model vulnerable for metabolic derangements. We therefore conclude...
  3. Mauritio

    Tetracyclines are anti-PUFA

    "Three important kinds of enzymes that are activated by stress and radiation are phospholipases (that release fatty acids), tryptophan hydroxylase (that controls the conversion of tryptophan to serotonin), and aromatase (estrogen synthetase, that converts androgens to estrogen). The products of...
  4. Mauritio

    Doxycycline for liver health

    Doxycycline is beeing increasingly studied for its anti-inflammatory effects at sub-antimicrobial doses. This study shows how and that it might be helpful in avoiding liver scarring/fibrosis. It shows that MMP-8, which is released in response to LPS, activates the hepatic stellate cells...
  5. Mauritio

    Coronavirus spike protein creates inflammation via CD147, antibiotics treat

    Another study on the infamous spike protein: So there's several studies showing that the SARS-cov-2 spike protein binds to a protein called basigin or CD147 . This can damage the pericytes in the heart, which can lead to aneurysms and other problems. CD147 is a marker of inflammation and...
  6. haidut

    Doxycycline can CURE melanoma in humans

    A great study and perhaps the first that confirmed in humans the already well-known anti-cancer effects of the tetracycline antibiotic family. Considering the almost complete ban on the word "cure" scientific journals have bestowed on cancer-related publications using non-mainstream therapies...
  7. UG Krishnamurti

    Doxycycline impairs oxidative metabolism and causes eczema and bad skin

    So I've fixed my eczema for the past 4 months by eating Ray's way and more importantly adding VIT K + D - which was the main culprit of getting rid of ezcema first time since my 20's. I've been eczema free up until 7 days ago when I started experimenting with doxycycline: 1 day: 300mg doxy 2...
  8. UG Krishnamurti

    Chest/Lung/Back Pain - Like a broken ribcage

    So I remember I was a kid and I had these intense chest pain where I couldn't even walk from the pain - did the MRI and all the tests and everything was fine. [ It's also at the opposite side of the chest - the whole back area ] It's also some feeling of stiffness like I cannot...
  9. haidut

    The Tetracyclines Protect Against Sepsis Independently Of Their Antibiotics Effects

    A remarkable study, which demonstrates that not all antibiotics have been created equal. Namely, the tetracycline family of antibiotics is strikingly protective against lethality from sepsis, and that protection is completely separate from their antibiotics effects. For example, the study...
  10. haidut

    Doxycycline Akin To Meldonium / Mildronate, May Cure Triple-negative Breast Cancer

    Once again, the role of excessive fat oxidation is on full display. While mainstream medicine is slowly and reluctantly admitting that cancer may in fact be a metabolic disease, it still views glucose as the primary oncogenic factor in the diet. Yet, little by little, research demonstrates that...
  11. haidut

    Doxycycline Effective In Human Trial For Breast Cancer

    It seems that medicine is finally starting to wake up from its slumber that has now lasted almost a century. I posted a few other studies on the effects of antibiotics used as cancer treatment. Those older studies also used doxycycline but other antibiotics from the same group like tetracyline...
  12. O

    Doxycycline (low And High Doses)

    I thought this was a tasty study about the difference between low and high dose doxy for (in this study) skin issues. But the authors also mention cardiovascular, neurological issues. I thought it was interesting that the authors explicitly call low dose doxy an "anti-inflammatory" dose. Lots...
  13. P

    Blocking Human Fear Memory With The Matrix Metalloproteinase Inhibitor Doxycycline

    Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline D R Bach , A Tzovara & J Vunder Molecular Psychiatry doi:10.1038/mp.2017.65 Download Citation Neuroscience Received: 05...
  14. P

    Anabolic ,DHT Supporting Effect Of Doxycycline In Osteoblasts

    Lol sorry , couldn't find better tittle for this. Probably low, nonantibacterial dose of doxycycline is what we need for these effects. Like 20-40mg a day. Antioxidant Response of Osteoblasts to Doxycycline in an Inflammatory Model Induced by C-reactive Protein and Interleukin-6 Objectives...
  15. P

    Low Dose Doxycycline Decreases Systemic Inflammation And Improves Glycemic Control, Lipid Profiles,

    Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in <i>db/db</i> mice Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in...
  16. P

    Positive Effect Of Tetracycline Antibiotics On Bones

    Even subantimicrobical dose, improves bone quality . And apparently minocycline is the best tetracycline. But doxycycline is also interesting. Effects of tetracyclines on bones: an ambiguous question needs to be clarified. - PubMed - NCBI Effects of tetracyclines on bone metabolism. -...
  17. haidut

    Niacinamide And Doxycycline May Treat Alzheimer Disease (AD)

    This study is yet another one that shows benefit of raising NAD levels for treating neurodegenerative conditions like AD. There were a few older studies around 2003, which were also done on mice and as a result of those studies a human clinical trial with 3g niacinamide daily (a dose that...
  18. T

    Blocking PTSD With Doxycycline

    With likely implications around learned helplessness. "We find that recall of threat memory, measured with fear-potentiated startle 7 days after acquisition, is attenuated by ~60% in individuals who were under doxycycline during acquisition... Our findings support an emerging view that...
  19. haidut

    Achilles Heel Of Cancer Found - Its Addiction To Fat

    The public propaganda message has always been that cancer cells are addicted to glucose. As a result of that belief, one of the so-called "new wave" therapies in the treatment of cancer is to "starve" the cancer cells of glucose and hope that they die on their own. This usually has disastrous...
  20. haidut

    Aspirin, Doxycycline, Lysine And RU486 Combo Prevents Cancer Metastases

    Yet another confirmation that there is general change of direction in cancer research after the complete failure of the "War on Cancer" since it first started in the 19070s. The journal OncoTarget where this study was published is one of the bastions of "cut, poison, burn" dogma. More...
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