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disease

  1. haidut

    The Human Organism Is An "electrome" And Diseases Can Be Cured By Controlling Electron Flow

    A great article describing the forgotten idea that the human organism is not simply a "wetware" of cells generated according to a master blueprint (DNA). Apparently, as early as the 1920s there were devices that could diagnose even very early stage cancer by simply measuring voltage difference...
  2. haidut

    (Brain) Cancer Is A Metabolic Disease, Can Be Treated By Glutamine Restriction

    It seems that mainstream medicine is finally wisening up to the massacre they have been orchestrating for the last 100 years. Without much fanfare or apologies, medicine is now quietly changing its story on cancer, hoping the public won't notice as long as a cure is finally found. The study...
  3. haidut

    GWAS Predicting Height Were Wrong; Same May Be True For Disease-prediction

    You have to appreciate the synchronicity (Synchronicity - Wikipedia) in nature. Just days after I posted the study on the role of diet in height, another study calls into question the validity of genetic factors in height...
  4. haidut

    Mitochondria (energy) As The Main Driver Of Health, Intelligence, And Aging

    We are finally starting to see Peat enter the mainstream and article like the one below are calling for a complete review of what we know about health and aging and how intelligence is tied to them. As the authors says, or actually borrows from Peat, there is solid evidence that mitochondrial...
  5. haidut

    Epidemic Of NAFLD And NASH In Young People

    Yet another sad reminder of just how much the health of the average person has declined over the last 20 years. They truly are becoming the "new old". The "Young" Have Now Become The Old If these trends are not reversed or at least slowed down, we may start seeing people in their 20s filing for...
  6. haidut

    Most People Recover From "addiction" On Their Own

    We have discussed the issue of "addiction" many times on this forum. Starting with the "Rat Park" experiment in the 1970s, there have been numerous studies showing that "addiction" is nothing but a desperate attempt at self medication as a way to limit the effects of chronic stress. Addiction...
  7. haidut

    Mitochondria Likely Determine Disease Risk, Not The Main Genome / DNA

    As I mentioned several times on Danny's podcasts, the genetic approach to curing disease has not really produced much for the last 80 years so little by little the industry is shifting its focus on metabolism. However, that shift won't happen overtly by admitting metabolism is key. Rather, it...
  8. haidut

    Stress As The Underlying Cause Behind ALL Chronic Diseases

    One of the more controversial of Ray's statements is that chronic stress is the underlying cause of many/most chronic conditions, especially autoimmune ones. In several of his articles he describes the role tissue damage under the influence of cortisol and estrogen play in creating an immune...
  9. haidut

    Saturated Fat (palmitate) Does NOT Activate TLR4

    We must have had hundreds of discussions on this topic on the forum. Some forum users strongly believe that saturated fat (SFA) increases inflammation by binding to and activating the endotoxin (LPS) receptor TLR4. Among all SFA, palmitate is the one most commonly blamed and has been...
  10. haidut

    The 'omnigenic' Theory Confirmed Again, Genomic Medicine Likely Useless

    About a year ago I posted a study showing that every gene apparently affects every other gene. Together, the fully (as opposed to sparsely) connected network of genes affects not only every disease risk but also every trait of the organism including height, eye color, skin color, etc. Every...
  11. haidut

    Everything Big Data Claims To Know About You May Be Wrong

    As many of you suspect by now, the whole push for the massive collection of human health data is probably not going to lead to any breakthrough cures/treatments. While the algorithmic analysis of massive data sets certainly has its value in terms of determining population-level or even global...
  12. haidut

    Niacinamide May Be A Viable Treatment For Parkinson Disease (PD)

    It looks like the pharma industry is experiencing a resurgence in the search for metabolic therapies with patented chemicals. There must have been at least 50 different studies in 2017 alone with the NAD precursor nicotinamide riboside (NR) for conditions ranging from cancer, to glaucoma, to...
  13. haidut

    Workplace Stress Is Literally Killing People; Mass Lawsuits Are Imminent

    It is good to see that even business school people - that bastion of workaholism - are finally opening their eyes to what the modern workplace is doing to the health of the populace. Even though I think this realization will fall on deaf years when it comes to executives changing the work...
  14. haidut

    Environment (diet), Not Genetics, Mainly Shapes Gut Bacteria Composition

    As many forum users know, studying the microbiome is the current hot topic in biochemistry and imbalances in the microbiome are used to explain everything from depression, to CVD, to cancer. A major argument advanced in the microbiome analysis field is that genes are the main driver of the...
  15. haidut

    Even A Slight Increase In Estrogen Strongly Decreases DHEA Levels

    I posted a few studies in the past revealing that in old age (and menopause) the levels of pregnenolone, progesterone and DHEA declines, while that of cortisol and aldosterone stays the same or even increases. Pregnenolone, Progesterone And DHEA Drop, Cortisol Rises In Aging The decline in...
  16. haidut

    Higher Fat Diets And Fat Emulsification Increase Endotoxin (in Obese Males)

    High dietary fat is one of the primary factors for increased endotoxin load, especially if the fat is PUFA. This is probably one of the main reasons Peat prefers lower fat diets. However, most of the studies on the fat-endotoxin link so far have been on animal models. This new human study...
  17. haidut

    Every Gene Affects Every Trait, So Personalized/genomic Medicine Is Doomed

    As one of the article says, there has been a boom in the so-called genome-wide association studies over the last decade. However, these studies have resulted in no reliable leads for genetic causes of disease. A new study at Stanford suggests that the reason this is so is that in fact ALL genes...
  18. haidut

    Stress (from Poverty) Leads To Early Puberty And Health Problems In Adulthood

    I recently posted a study on the effects of pregnancy stress (cortisol) on the development and aging of an organism. Chronic Stress During Pregnancy Accelerates Fetal Aging And Harms Its Health Peat also wrote that virtually all features of aging can be produced by administering a large dose of...
  19. haidut

    Epigenetic Changes Can Be Passed Down For At Least 14 Generations

    The phenomenon of inheritance is a solidly established fact in medicine. The fact that having relatives who had chronic disease increases one's own risk for developing those diseases is one of the main arguments of the pro-genetic crowd given as a reason to pursue genetic explanation of...
  20. haidut

    Another Study Links PUFA To Alzheimer Disease (AD)

    I posted some studies a few months ago, which showed that PUFA metabolites are elevated in patients with AD, and that blocking PUFA metabolism can reverse the pathology (in an animal model). Increased Pufa Oxidation May Be Biomarker For Alzheimers Blocking PUFA Metabolism May Reverse Alzheimer...
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