diabetes

  1. haidut

    The Financial Crisis In 2008 Increased Obesity, Diabetes And Mental Illness

    So much for these issues being "predominantly genetically driven" as mainstream medicine likes to proclaim. It would have been nicer if the authors of the study also tested thyroid function as that would have directly implicated declining metabolism in these health issues strongly linked to...
    • haidut
    • Thread
    • anxiety chronic stress depression diabetes financial crisis great recession mental health obesity recession uncertainty
    • Replies: 13
    • Forum: Scientific Studies
  2. P

    Glycine Enhances Expression Of Adiponectin And IL-10 In 3T3-L1 Adipocytes Without Affecting Adipogen

    https://www.ncbi.nlm.nih.gov/pubmed/29356901 Amino Acids. 2018 Jan 22. doi: 10.1007/s00726-018-2537-3. [Epub ahead of print] Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis. Chen J1, Ma X1, Yang Y1, Dai Z1, Wu Z2,3, Wu G1,4...
  3. haidut

    Anti-adrenaline Drugs Like Clonidine May Prevent Diabetes Type I

    Peat mentioned a few times that the pancreatic damage seen in type I diabetes is caused by prolonged exposure to PUFA, as unsaturated fats are toxic to the insulin-producing beta cells in that organ. Many of the cases of new onset diabetes I occur after a period of extreme exhaustion and/or...
    • haidut
    • Thread
    • adrenaline autoimmune beta cells clonidine diabetes epinephrine ffa insulin methyldopa pancreas pufa
    • Replies: 10
    • Forum: Scientific Studies
  4. P

    Low Dose Doxycycline Decreases Systemic Inflammation And Improves Glycemic Control, Lipid Profiles,

    Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in <i>db/db</i> mice Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in...
    • paymanz
    • Thread
    • a1c adiponectin advanced glycation end products antiinflammatory apoptosis beta cells diabetes doxycycline endotoxin glycogen inflammation insulin insulin resistance insulin sensitivity lps minocycline mmp inhibitor obesity tetracycline tnf
    • Replies: 5
    • Forum: Articles & Scientific Studies
  5. Mr. God of Cars

    Is Diabetes Really The Inability To Oxidize Sugar?

    Ray Peat said: ° "Saturated fats activate the pyruvate dehydrogenase enzyme that is essential for the efficient use of glucose, while PUFA block it." [1, 1.5] ° "In the 1940s, Bernardo Houssay found that coconut oil protected animals from poison-induced diabetes, while a lard-based diet...
  6. P

    Skeletal Muscle Phosphatidylcholine And Phosphatidylethanolamine Are Related To Insulin Sensitivity

    And the difference is big! 100% and 50% for each ,compared to subjects with higher insulin sensitivity. Egg yolks/milk and liver are rich source of these phospholipids. But yolks are the richest. Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin...
    • paymanz
    • Thread
    • choline diabetes eggs folate insulin sensitivity magnesium membrane fluidity milk phosphatidylcholine phosphatidylethanolamine phosphatidylserine phospholipid pufa saturated fat sphingomyelin taurine vitamin a vitamin k zinc
    • Replies: 58
    • Forum: Articles & Scientific Studies
  7. haidut

    Androgen Deficiency As The Main Cause Of Chronic Disease In Males

    This is one of the most comprehensive reviews that I have ever come across on the topic of androgens and their role in male health. It is authored by one of the most renowned experts in urology - the former director of the Department of Urology at Boston University (BU) School of Medicine. Given...
    • haidut
    • Thread
    • aging androgen deficiency androgen deprivation cvd dht diabetes dutasteride finasteride heart attack heart disease hepatocellular carcinoma insulin resistance liver cancer liver disease males mitochondrial dysfunction nafld sexual dysfunction stroke testosterone
    • Replies: 108
    • Forum: Scientific Studies
  8. P

    Statins May Exert Beneficial Effects Through A Pathway Other Than It's Cholesterol Lowering Action

    Was surprised when saw a study showing statins have positive effects on bones, did a bit of searching and it turned out that it has some positive action,generally, through inhibiting rho kinase, which also is protective against heart disease. Im not promoting statin use at all(for obvious...
    • paymanz
    • Thread
    • aspirin bone health calcitriol cancer cholesterol depression diabetes erectile dysfunction fibrosis histamine hypertension osteocalcin osteoporosis parkinson's rho-kinase salicylates statins taurine vitamin d
    • Replies: 8
    • Forum: Articles & Scientific Studies
  9. P

    Betaine Lowers FFA And Improve Insulin Sensitivity And Adiponectine Level In High Fat Fed Animal

    Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease Endoplasmic reticulum (ER) stress plays a critical role in adipose tissue dysfunction and insulin resistance in a variety of experimental...
    • paymanz
    • Thread
    • adiponectin betaine choline diabetes fibrosis free fatty acids insulin resistance insulin sensitivity jnk leptin liver disease liver steatosis resistin
    • Replies: 7
    • Forum: Articles & Scientific Studies
  10. haidut

    Children Drinking Whole Milk Are Leaner Than Ones Drinking Skim Or Low Fat Milk

    I know Peat has mentioned a few times that people do not drink whole milk, but it appears the extra calories from whole milk are actually not the issue in weight gain, at least not in children. As I posted in my thread on the endotoxin theory of CVD, obesity is an endocrine disorder driven by...
    • haidut
    • Thread
    • children diabetes low-fat milk obesity skim vitamin d vitamin d3 whole
    • Replies: 89
    • Forum: Scientific Studies
  11. haidut

    Endotoxin (LPS) Theory Of Atherosclerosis (CVD)

    I posted a study more than year ago, which examined the role of NO in aging and disease. The Nitric Oxide (NO) Theory Of Aging One of the main endogenous stimulators of NO synthesis is endotoxin (LPS). It turns out that the connection between LPS and CVD has been studied for a long time in...
    • haidut
    • Thread
    • atherosclerosis causative cvd diabetes endotoxin inflammation insulin resistance lps obesity stress stroke tlr4
    • Replies: 24
    • Forum: Scientific Studies
  12. haidut

    SSRI Use In Children Dramatically Increases Risk Of Diabetes In Adulthood

    The bad news for SSRI just keep on piling. Given serotonin's role as a master metabolic inhibitor this findings is not really surprising. There are a number of clinical trials underway with serotonin synthesis (TPH) inhibitors as treatment of obesity, insulin resistance and diabetes II. As of...
    • haidut
    • Thread
    • adulthood children chronic use diabetes high dose increase long-term use risk serotonin ssri
    • Replies: 3
    • Forum: Scientific Studies
  13. haidut

    More Than One Third Of Americans Have Diabetes Or Pre-diabetes

    So much for the "indisputably improving" health of the nation as every HHS secretary since the Vietnam War has officially claimed. Up until recently the claim was that while the nation was getting quite visibly obese by the day that was not translating into adverse health outcomes. Well, so much...
    • haidut
    • Thread
    • america diabetes insulin resistance obesity pre-diabetes rates rising usa
    • Replies: 8
    • Forum: Scientific Studies
  14. Mito

    Relation Of Total Sugars, Fructose And Sucrose With Incident Type 2 Diabetes

    BACKGROUND: Sugar-sweetened beverages are associated with type 2 diabetes. To assess whether this association holds for the fructose-containing sugars they contain, we conducted a systematic review and meta-analysis of prospective cohort studies. INTERPRETATION: Current evidence does not allow...
  15. Mito

    Chronic Fructose Substitution For Glucose Or Sucrose In Food Or Beverages Has Little Effect On Fasti

    Conclusions: The evidence suggests that the substitution of fructose for glucose or sucrose in food or beverages may be of benefit to individuals, particularly those with impaired glucose tolerance or type 2 diabetes. However, additional high-quality studies in these populations are required...
  16. haidut

    Alzheimer Disease (AD) May Be Simply Diabetes Of The Brain

    I touched upon this topic in one of the Danny Roddy shows we did last year but the evidence since then has continues to accumulate that AD is entirely a metabolic disorders, basically identical to diabetes but focusing on the brain. A recent study found that delirium, an acute form of...
    • haidut
    • Thread
    • ad alzheimer's brain dementia dhea diabetes glucose inhibitor insulin resistance memantine potassium channel
    • Replies: 13
    • Forum: Scientific Studies
  17. haidut

    A Subset Of Diabetes I Can Be Cured By Vitamin B1 (thiamine)

    I don't know much about this apparently genetic form of neonatal diabetes I, but looking at the mutation in question I do not see how it related to thiamine at all, yet thiamine is therapeutic. So, the question that naturally arises is - can thiamine potentially help all cases of diabetes I...
    • haidut
    • Thread
    • diabetes insulin mutation neonatal reversal thiamine treatment
    • Replies: 12
    • Forum: Scientific Studies
  18. haidut

    Low-dose Aspirin As Treatment For Kidney Disease / Failure

    Just wanted to post here as diabetes is perhaps the most common chronic disease in the world and many diabetes sufferers have kidney disease, which is considered irreversible. However, as this clinical trial states (and as Peat said as well), the kidney damage seems to be due to inflammation...
    • haidut
    • Thread
    • aspirin cox diabetes inflammation kidney disease kidney failure pufa treatment
    • Replies: 20
    • Forum: Scientific Studies
  19. haidut

    A Record Number Of Americans Suffer From Severe Psychological Distress (SPD)

    I am posting this study in support of other recent studied I posted on increases of chronic disease rates in young people, especially stroke and diabetes I. Stroke Rates Have Almost Doubled In Young Adults Rates Of Diabetes I And II Are Rapidly Rising In Young Children And Teens Health Of Young...
    • haidut
    • Thread
    • depression diabetes distress health mental number psychological record severe spd stroke
    • Replies: 50
    • Forum: Scientific Studies
  20. haidut

    Rates Of Diabetes I And II Are Rapidly Rising In Young Children And Teens

    I posted recently the rather sad finding that colon cancer rates have doubled in young people. Colon cancer is one of the cancers considered solidly an "old person" cancer and one with strong genetic component (like most cancers according to the FDA). Breaking News: Colorectal Cancer Rates In...
    • haidut
    • Thread
    • children diabetes genes metabolic rates rising teens young
    • Replies: 36
    • Forum: Scientific Studies
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