dht

  1. haidut

    Androgens Boost, Estrogen Inhibits, Anti-aging Gene Klotho

    This post has two main messages, based on the studies below. Namely, androgens (and especially DHT) potently increase the expression of the anti-aging gene Klotho while estrogens strikingly decrease its expression. Moreover, the more potent the androgen, in terms of androgen receptor (AR)...
    • haidut
    • Thread
    • aging androgen anti-aging dht espression estrogen gene klotho
    • Replies: 2
    • Forum: Scientific Studies
  2. haidut

    Estrogen Lowers T, DHT, And Fertility; Inhibits 5α-Reductase (5-AR)

    I am posting this study below as a response to numerous angry emails I have been getting over the years. People sending me those emails just cannot accept the idea that estrogen can be detrimental for males (and females as well), and that estrogen levels are directly antagonistic to the male...
    • haidut
    • Thread
    • 5-ar dht estradiol estrogen fertility leydig testosterone
    • Replies: 13
    • Forum: Scientific Studies
  3. Drareg

    Danish Largest Mask Study Refused Entry Into "scientific Journals"

    Just when you think the censoring couldn’t stoop lower this has made the front page of a Danish newspaper, it will going out tomorrow and I will post the link then, it’s in Danish. For now here’s a twitter link-https://twitter.com/MaMoMVPY/status/1319002978146263040 Basically the usual suspects...
  4. Hans

    The Truth On DHT: What The Research Shows

    Hi all, There is a common misconception that DHT causes prostate cancer, hair loss and what else not. I've been sifting through the research on what the effects of high DHT actually is and what happens if men take large doses of DHT for long periods of time. Here are my findings: The truth on...
    • Hans
    • Thread
    • bone cardiovascular disease coronary artery disease dht hair loss insulin sensitivity metabolic syndrome muscle prostate cancer
    • Replies: 23
    • Forum: Articles & Scientific Studies
  5. Lokzo

    Dihydrotestosterone (DHT) Enhances Wound Healing Of Major Burn Injury

    Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice
  6. haidut

    Aromatase Inhibitor (AI) + DHT Combo May Reverse Kidney Disease (CKD)

    A truly great study for a number of reasons. First, it cites extensive evidence that male patients with diabetes (both types) have low androgens and high estrogen (estradiol). The association between this endocrine abnormality and the severity of diabetes is apparently quite strong, yet it is...
    • haidut
    • Thread
    • androgen aromatase inhibitor ckd dht diabetes estradiol estrogen kidney disease
    • Replies: 4
    • Forum: Scientific Studies
  7. haidut

    Topical DHEA Has Potent Anti-aging Effects On Human Skin

    I often get emails in regards to possible interventions with anti-aging effects on skin. The study I usually quote is an old one (circa 1967) that did extensive tests on 200+ people with age range of 57-88 years residing in a retirement home, and demonstrated that topical testosterone (1%) cream...
    • haidut
    • Thread
    • androgen anti-aging dhea dht pregnenolone progesterone rejuvenate skin
    • Replies: 22
    • Forum: Scientific Studies
  8. S

    DHT And Reversing Androgen-receptor Deficiency

    I'll make this thread as short as I can: A few years ago, I ran gear stupidly and developed what seems to be identical to Post-finasteride syndrome (deca is notorious for causing problems). I've read Proviron/DHT creams seem to reverse the problem. The problem is, I can't seem to find any...
  9. E

    DHT Decreases Adrenal Androgens

    Although it's not directly DHT, study says Proviron (Mesterolone) decreases adrenal androgen synthesis which is a marker of poor gonadal function. That means it increases gonadal function. It also increases aldosterone? Profiling of Anabolic Androgenic Steroids and Selective Androgen Receptor...
  10. haidut

    DHT Is Negatively Associated With Death From Prostate Cancer

    Just a quick study that, despite being epidemiological, raises serious questions about the validity of the "androgen-driven" hypothesis of prostate cancer. If the assumption is that DHT is the primary driver of prostate cancer it is hard to come up with any plausible explanation of how the...
    • haidut
    • Thread
    • androgen dht dihydrotestosterone lethality mortality prostate cancer reduce
    • Replies: 4
    • Forum: Scientific Studies
  11. haidut

    Estrogen, Not Androgens, May Be The Cause Of Baldness

    A quick post about a study calling into question yet another dogma in medicine - i.e. that the "evil" androgens (especially DHT) are the causes of men losing their hair and getting prostate cancer. So, the "solution" modern medicine proposes is "chemical castration" with drugs like finasteride...
    • haidut
    • Thread
    • androgen baldness cause dht estradiol estrogen hair loss
    • Replies: 164
    • Forum: Scientific Studies
  12. B

    Haidut's Recent Comments On Estrogen's Role In Hairloss

    In today's livestream Georgi and Roddy talked a lot about hairloss, specifically estrogen's (proposed) causative role. Georgi also talked about the side effects many people get when taking ai's like exemestane and anastrozole. For those who don't have time to watch the video, here are some of...
  13. haidut

    DHT May Be Vital For The Morphogenesis Of Organism(s)

    As many forum users know, the potent androgen DHT is one of the most vilified endogenous substances produced by the human body, second only to cholesterol. Aside from verbal vitriol published in mainstream scientific journals, this attitude of medicine towards DHT can also be estimated from the...
    • haidut
    • Thread
    • 5-ar dht dihydrotestosterone dutasteride field finasteride morphogenesis shape
    • Replies: 13
    • Forum: Scientific Studies
  14. haidut

    Lowering DHT Synthesis Causes Severe Hypothyroidism, Despite Higher T Levels

    Just a quick post in regards to one of the most controversial steroids out there - dihydrotestosterone (DHT). Mainstream medicine has vilified this steroid for decades and has blamed a host of male and female pathologies on it - i.e. baldness, prostate enlragement (BPH), prostate cancer (PC)...
    • haidut
    • Thread
    • 5-ar 5α-reductase cause dht dihydrotestosterone finasteride hypothyroidism severe testosterone
    • Replies: 21
    • Forum: Scientific Studies
  15. J

    What Explains Extreme Body Hair/beard But MPB?

    I've seen this a lot in middle eastern cultures where the body hair is like a thick fur coat and the thickest facial hair possible... but serious mpb on the top. What explains this form of hair loss where hair is thriving in higher than average amounts everywhere except the top of the head?
    • Jack Earth
    • Thread
    • adrenal androgens body hair dhea dht hair loss hirsutism mpb
    • Replies: 214
    • Forum: Hair & Nails
  16. haidut

    Drop In Androgen Levels Causes Parkinson Disease (PD), DHT Reverses It

    Yet another study demonstrating that many of the so-called chronic, degenerative and above all "mysterious" conditions often have quite a simple cause and, potentially, treatment. There is no need for mutated genes or complex interactions of genes with environment that nobody can decipher...
    • haidut
    • Thread
    • 5α-dihydrotestosterone androgen brain castration cns dht dopamine gdnf inos neurodegeneration neurodegenerative neuroinflammation nitric oxide no parkinson parkinson's disease testosterone α-synuclein
    • Replies: 41
    • Forum: Scientific Studies
  17. haidut

    DHT May Treat Prostate Cancer, Estrogen (E2) Strongly Promotes It

    As I have posted many times over the last 4-5 years and discussed numerous times on Danny Roddy's podcasts, the so-called "androgen hypothesis" (as in androgens being a cause) of prostate cancer appears to be little more than untenable conjectures often combined with outright fraud. What's...
    • haidut
    • Thread
    • cause cure dht estradiol estrogen fraud prostate cancer scam treat
    • Replies: 2
    • Forum: Scientific Studies
  18. haidut

    Drostanolone (a DHT Isomer) May Treat Prostate Cancer

    The bad news for the DHT-driven theory of prostate cancer just keep piling on. There have been at least 3 human trials in the last 5 years demonstrating that the direct injection of testosterone (T) into the prostate can stop advanced, inoperable prostate cancer. There are also studied showing...
    • haidut
    • Thread
    • androgen chemotherapy cure dht drostanolone isomer potent prostate cancer therapeutic treat
    • Replies: 8
    • Forum: Scientific Studies
  19. haidut

    Androsterone May Be The Main Source Of DHT, Drives Fetal Masculinization

    The study below demonstrates that not only may androsterone be the primary pro-hormone used endogenously for DHT synthesis, it likely also drives the masculinization of sexual organs in the fetus. For a long time it was thought that the so-called "front pathway" using testosterone (T) produced...
    • haidut
    • Thread
    • androgen androsterone backdoor development dht fetal fetus genitalia human male masculinization offspring pathway penis precursor pro-hormone source
    • Replies: 90
    • Forum: Scientific Studies
  20. D

    Study Found Positive Correlation Between Iron And Total +free Testosterone, Higher T3, DHT

    Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with mal... - PubMed - NCBI we found positive correlations between the concentrations of TT-Mg, TT-Fe, TT-Mo, FT-Fe, So iron has a positive correlation...
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