depression

  1. haidut

    Hyperthermia As Treatment For Depression

    I was pleasantly surprised to see this recent study, but unfortunately the rationale given for its positive findings suggests that the irrational research on serotonin will continue (as Peat said). The study used whole-body heating and found that this hyperthermia resulted in strong decrease of...
    • haidut
    • Thread
    • depression hyperthermia infrared light metabolism red light relieves
    • Replies: 10
    • Forum: Scientific Studies
  2. P

    Antidepressant-like Effect Of Creatine In Mice Involves Dopaminergic Activation

    Antidepressant-like effect of creatine in mice involves dopaminergic activation. - PubMed - NCBI Abstract Creatine has been shown to play a significant role in health and disease. However, studies concerning its effect on mood are scarce. This study investigated the effect of creatine (p.o.)...
    • paymanz
    • Thread
    • creatine depression dopamine dopaminergic study tryptophan
    • Replies: 15
    • Forum: Scientific Studies
  3. S

    Tianeptine Vs Escitalopram

    Influence of anxiety symptoms on improvement of neurocognitive functions in patients with major depressive disorder: A 12-week, multicenter, random... - PubMed - NCBI http://tinyurl.com/hyuogod
  4. haidut

    LSD Forces People To Think About The Present/future And Not The Past

    I have written before about the well-known tendency of people with depression, PTSD, and other traumatic disorders to ruminate and focus intensively on analyzing past events. This is one of the reason people with such conditions tend to abuse alcohol. In addition to temporarily lowering stress...
    • haidut
    • Thread
    • depression future health lsd metabolism past rumination thinking
    • Replies: 72
    • Forum: Scientific Studies
  5. tonto

    Is Serotonin An Upper Or A Downer?

    (my first post, love the site!) I found this article* a few months ago and thought others on this site would like it if it hasn't been shared before. Some highlight for me was the section on "the serotonin system and energy regulation", and the understanding by the authors that serotonin is...
  6. Luann

    Why & How Not To Fear Cholesterol

    Hi guys, found these two gems today, I was trying to explain the short fuse I've had at work lately as well as getting the blues out of nowhere. Turns out cholesterol level has a little something to do with the way you feel, ya know, on the inside. Enjoy these - and get some coconut oil today if...
  7. haidut

    Methylene Blue As A Treatment For Manic Depressive Psychosis

    The study was on bipolar disorder psychosis, which is different from the psychosis in conditions like schizophrenia. The psychosis of bipolar disorder is believed to be caused by cortisol, and since methylene blue helped then it suggests methylene blue can lower excessive cortisol. This is not...
    • haidut
    • Thread
    • bipolar disorder depression disorder manic methylene blue psychosis study
    • Replies: 6
    • Forum: Scientific Studies
  8. P

    A Controlled Trial Of Methylene Blue In Severe Depressive Illness

    A controlled trial of methylene blue in severe depressive illness. - PubMed - NCBI Abstract Methylene blue, 15 mg/day, was compared with placebo in treatment of severe depressive illness. The 3-week trial was designed to avoid bias by placebo response and also to avoid observer bias...
  9. haidut

    Depression Is A Systemic Disease Linked To Pufa Oxidation

    This study is very important, but unfortunately politics once again has limited the way it is being interpreted. The first major point of the study is that depression is not a local (neurological) but rather a systemic condition. The second major point is that depression symptoms were linked to...
    • haidut
    • Thread
    • depression disease malondialdehyde oxidation pufa systemic
    • Replies: 5
    • Forum: Scientific Studies
  10. haidut

    Dmso Is Similar To Reserpine, Lowers Serotonin, Increases MAO-A

    I have suspected that DMSO has central effects given how powerfully sedating it can be for some people. This older study compares the effects of DMSO to the ancient tranquilizer reserpine, which Peat has written about before. This would make DMSO an effective serotonin lowering agent, an...
    • haidut
    • Thread
    • depression dmso mao-a methylene blue psychosis reserpine serotonin
    • Replies: 45
    • Forum: Scientific Studies
  11. haidut

    Amazing Medicinal Properties Of Beta-lapachone (β-lapachone)

    This thread is similar to the one I created for emodin and in support of the Lapodin supplement I released. Lapodin: Lapodin - Dietary Supplement With Beta-lapachone And Emodin | Ray Peat Forum Emodin: Amazing Medicinal Properties Of Emodin | Ray Peat Forum The purpose of this thread is to...
    • haidut
    • Thread
    • antibacterial antifungal antiviral beta-lapachone cancer cortisol cvd depression diabetes endotoxin estrogen inflammation lapachone nad napththoquinone neurological nitric oxide obesity serotonin β-lapachone
    • Replies: 22
    • Forum: Supplements
  12. J

    Freewheel Running Prevents Learned Helplessness (How Would This Fit Into Peat's View Of Exercise?

    Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons. Greenwood BN1, Foley TE, Day HE, Campisi J, Hammack SH, Campeau S, Maier SF, Fleshner M. Author information Abstract Serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) are...
    • James_001
    • Thread
    • depression excercise freewheel running learned helplessness study
    • Replies: 5
    • Forum: Exercise
  13. M

    Trouble Quitting Cannabis

    Hello, I'm a 45 year old (gasp) mom and my 'mother's little helper' is in the form of a vaporizer and weed which I'm told is organically grown. My usage amount varies but I usually do 2-3 cycles (like 10 puffs) once, sometimes twice, per day. I thought I could keep it under control but my...
  14. haidut

    Cyproheptadine As A Powerful Antidepressant

    This study shows a number of key points central to Peat's views. Cortisol secretion is under the control of serotonin, and as such cortisol and serotonin are high in depression. Most effective antidepressants are antagonists of serotonin and lower cortisol as well. This includes some the dreaded...
  15. haidut

    Caffeine - A "new" Drug For Depression / Social Defeat

    Caffeine has been popping up in the news lately. Several studies caught my eye, so I am posting them here. Two independent groups of researchers found out that caffeine protects against stress-induced mood and memory dysfunction. One of the studies focused on depression and found that increase...
  16. natedawggh

    Uridine Monophosphate For Fatty Liver/weight Problems/depression/anxiety/insomnia

    From a Ray Peat view of the organism (humans), it is generally viewed that all degenerative conditions are interrelated in one way or another. As is in my experience, mental and physical problems go hand in hand and rarely ever present singularly. The major themes of my struggles have been...
    • natedawggh
    • Thread
    • anxiety depression insomnia nafld supplemental uridine weight
    • Replies: 31
    • Forum: Articles
  17. haidut

    More On The Wrong Theory Of Depression And Serotonin

    It seems like these articles are popping everywhere. I wonder if this trend continues and erodes sales of Prozac et al then what will the pharma industry come up with as next generation drugs. Also, does anybody go to jail for knowingly pushing SSRI drugs responsible for thousands of suicides? I...
  18. haidut

    Lack of serotonin makes one immune to depression

    Not sure why this is not hitting the news everywhere, but I find it particularly telling as to whether serotonin is good of bad for depression. http://www.researchgate.net/profile/Don ... ehavioral_ Phenotype/links/5411a2ba0cf2b4da1bec5e20.pdf http://www.sciencedaily.com/releases/20 ...
  19. haidut

    Study confirms science behind serotonin and depression is backwards

    What can I say - Ray is right once again, which we knew from the start. In the words of the actual study - "serotonin is a downer". It appears SSRIs work by forcing the brain to achieve homeostasis, not by modulating serotonin levels. Again, Ray did say that as well - i.e. drug companies did not...
  20. haidut

    Yet Again, Brain Inflammation Linked To Depression

    This is the first time I see a scientist propose officially that depression be treated with anti-inflammatory drugs. I posted a study showing a human equivalent dosage of 500mg aspirin being a more effective antidepressant (in mice) than Prozac. I think the more important question is if...
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