depression

  1. haidut

    One Third Of US Adults Take Drugs That Cause Depression And Suicide

    I think this study goes a long way towards explaining the rapid rise in depression and suicide rates over the last 2 decades. The public has only recently become aware of the epidemic due to high profile suicides of celebrities like Anthony Bourdain and Kate Spade, among others. The fact that...
  2. haidut

    Major Depression Rates Rapidly Rising, Especially In Young People

    I posted a few studies in the past showing that rates for cancer, diabetes, and stroke have increased several-fold over the last decade, and mostly in young people. The official version peddled by the FDA of course is that we just keep getting healthier by the minute and life expectancy is...
  3. haidut

    The Financial Crisis In 2008 Increased Obesity, Diabetes And Mental Illness

    So much for these issues being "predominantly genetically driven" as mainstream medicine likes to proclaim. It would have been nicer if the authors of the study also tested thyroid function as that would have directly implicated declining metabolism in these health issues strongly linked to...
  4. P

    Blocking Human Fear Memory With The Matrix Metalloproteinase Inhibitor Doxycycline

    Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline D R Bach , A Tzovara & J Vunder Molecular Psychiatry doi:10.1038/mp.2017.65 Download Citation Neuroscience Received: 05...
  5. haidut

    Chronic Fatigue Syndrome (ME/CFS) May Be Caused By Increased Serotonin Sensitivity

    Despite the denials of mainstream medicine that CFS exists as an organic disorder, many studies have been done on the etiology of the fatigue and how it often follows an acute illness, usually of "viral" origin. Due to the fact that the role of serotonin in inducing fatigue is well-known...
  6. P

    Statins May Exert Beneficial Effects Through A Pathway Other Than It's Cholesterol Lowering Action

    Was surprised when saw a study showing statins have positive effects on bones, did a bit of searching and it turned out that it has some positive action,generally, through inhibiting rho kinase, which also is protective against heart disease. Im not promoting statin use at all(for obvious...
  7. haidut

    Environmental Enrichment As Effective As Drugs For Treating Depression

    This study is really good because not only it states directly that depression can be directly caused by stress, but also because it shows that environmental enrichment (EE) for just 20 days can be at least as therapeutic as drugs. The beneficial effects of EE are well-known in psychiatry and...
  8. haidut

    Bright Light May Treat Bipolar Disorder With The Same Response Rate As Lithium

    Bipolar disorder is one of the most difficult ones to treat and often requires hospitalization during episodes of acute mania. The god standard of treatment for this disorder is still lithium - a drug that has been in use for more than 100 years. This new study shows that simply getting...
  9. haidut

    Successful Antidepressant Drugs Are Glucocorticoid Antagonists

    Peat was asked a few times about his opinion on SSRI drugs and he said that 1) he does not recommend them because they are systemically serotonergic, and 2) their mechanism of action is really not what big pharma would have us believe. Since then, SSRI drugs that have been shown to actually work...
  10. haidut

    Nitrous Oxide (N2O) Prevents Suicidal Behavior, Reverses Learned Helplessness

    First, please note that this study is about nitrous oxide (N2O) and not nitric oxide (NO). There is a huge difference in effects despite the minor difference in chemical structure. Peat has written about both - the benefits of the former and the dangers of the latter. N2O is commonly known as...
  11. haidut

    Intrusive / Unwanted Thoughts Due To Low GABA Signalling

    Peat has mentioned GABA quite a few times in his articles and its role as the chief inhibitory signal in the body, protecting both brain cells and peripheral tissues/organs from excitotoxicity caused by PUFA, glutamate, estrogen, stress, etc. But the role of GABA is especially prominent in the...
  12. haidut

    Intelligent People More Likely To Suffer From Mental Illness

    I have mentioned a few times on the forum that in the "psychiatric bible" DSM IV/V a good mental health is characterized by a mild to moderate delusion, while realism is characterized by a mild to moderate depression. Peat said a few times that people with high IQ have a hard time adjusting to...
  13. haidut

    Stress Just As Bad As High-PUFA Diet For Your Health

    Most doctors consider stress to be an inescapable fact of daily life, but something that is of concern to only genetically pre-disposed people or ones who have CVD. The official version is that for most people stress does NOT cause adverse health outcomes. However, this house of cards has stated...
  14. haidut

    Altruistic People More Likely To End Up With Depression

    This study is very interesting because it explains a bit of the "paradox" observed numerous times in medical and psychology professions. Namely, altruistic and caring people in those professions have an abnormally high rate of depression and suicide compared to their more normal (read: selfish)...
  15. P

    Fibroblast Growth Factor-2 And Anxiety

    Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors - ScienceDirect Fibroblast growth factor deficiencies impact anxiety-like behavior and the serotonergic system. - PubMed - NCBI Fibroblast Growth Factor 2 for...
  16. haidut

    High Lactate May Be The Cause Of Major Psychiatric Disorders

    The study itself has a misleading title because there are quite a few situations that can result in lower brain pH (and thus high acidity). High levels of CO2 can also cause low brain pH levels, but as I posted in a few other studies drugs that raise CO2 levels can actually treat mental disease...
  17. haidut

    The Pursuit Of Happiness Makes Us Sad

    The message about activeliy pursuing happiness and the genetic basis of depression are probably two of the most deeply rooted memes in the Western world. Our reliance on the online medium to collect our daily ration of information is probably why most people are basking 24x7 in deliberately...
  18. haidut

    Low-dose Allopregnanolone Induces Relief From Depression In Just 24 Hours

    I posted a few studies on the powerful mood boosting effects of allopregnanolone in relation to its precursor 5a-DHP. The precursor 5a-DHP converts into allopregnanolone with almost 100% efficiency as it is the the only pathway through which it can be metabolized downstream. All successful...
  19. haidut

    Finasteride Causes Physical Damage To Nerves, Depression, ED, Steroid Imbalance

    After a decade of denying that a thing such as PFS exists, mainstream medicine seems to be wisening up to the fact that this poison does a lot more than lower the "bad" DHT. Up until very recently, it was common to simply measure blood steroid levels and then declare that they had rebounded upon...
  20. haidut

    A Record Number Of Americans Suffer From Severe Psychological Distress (SPD)

    I am posting this study in support of other recent studied I posted on increases of chronic disease rates in young people, especially stroke and diabetes I. Stroke Rates Have Almost Doubled In Young Adults Rates Of Diabetes I And II Are Rapidly Rising In Young Children And Teens Health Of Young...
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