depression

  1. NewACC

    Agmatine Is Wonder Drug (Endotoxins, Endorphins, Adrenaline, NO)

    As you can know agmatine is very interesting peaty chemical, but steel I want to show you some interesting and maybe less known articles Anti-endotoxin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923203/ "...agmatine treatment inhibited LPS-induced production of nitrates dose dependently. As...
  2. haidut

    Progesterone may help quitting smoking

    A very interesting article, on a topic that has been studied for decades but has not seen much mainstream media exposure mostly because it does not fit the narrative. Namely, that "addictions", including smoking, are mostly genetically determined and not much can be done about them except manage...
  3. haidut

    Even very low-dose endocrine disruptors induce learned helplessness, anhedonia

    Not much to comment on this study, considering the mountains of literature already available on the topic of endocrine disruptors such as BPA/BPA/DEHP, except to point out that the results were obtained even with very low-dose exposure to the harmful chemicals. Another interesting finding was...
  4. haidut

    BOMBSHELL: Serotonin High in Depression, Not a "Happy" Chemical, Lowers Energy, Depression Self-Resolves

    When I first saw the article pop up in my feed, I could hardly believe my eyes that a mainstream mouthpiece of Big Pharma will publish such frank admission of psychiatry's utter failure - i.e. the claims in regards to serotonin (5-HT), its role in mental illness, and even its social "label". In...
  5. haidut

    Just a week-long break from social media alleviates anxiety and depression

    I don't think this study will come as a surprise to my readers, but it still helps to have some peer-reviewed evidence confirming what many people intuitively sense, yet are afraid to verbalize due to FOMO or being ostracized - i.e. social media, and digitization in general, is a bane on human...
  6. haidut

    Higher PUFA intake correlated with mental disease

    An epidemiological study, yet still useful IMO since the correlation was maintained across the various levels of PUFA intake - i.e. the higher the PUFA intake the higher the prevalence of a mental disorder such as depression, which suggests a causal link. The link was the strongest in males and...
  7. haidut

    Dopamine agonists can treat anhedonia

    The title may sound obvious to many, but this study is one of the few to bring up the taboo topic of serotonin's role in symptoms of depression. The current dogma still holds that raising serotonin levels (or activating its receptors) is the most beneficial mechanism to treating depression and...
  8. haidut

    Young people are lonelier than ever

    The actual title of the article, covering recent studies about loneliness rates in Western populations. It dispels the convenient excuse that the "pandemic" is what caused this true epidemic of loneliness by showing those rates were high years before any talk about virus/lockdown entered the...
  9. haidut

    PUFA cause obesity, diabetes, autism, Alzheimer's disease, anxiety, and depression

    The title is an actual quote from the article, so there is no editorializing on my part and it speaks volumes about how the authors feel about their findings. In addition, opposite effects were found for saturated fats, in this case coconut oil, which leads the authors to once again remind...
  10. A

    Why Sleep Deprivation Eases Depression

    Wake therapy, a specific application of intentional sleep deprivation, encompasses many sleep-restricting paradigms that aim to address mood disorders with a form of non-pharmacological therapy. Wake therapy was first popularized in 1966 and 1971 following articles by Schulte and by Pflug and...
  11. A

    Elevating the level of hypoxia inducible factor may be a new potential target for the treatment of depression

    فاکتور 1 القایی هیپوکسی (HIF-1) یک فاکتور رونویسی است که بیان ژن را در پاسخ به کاهش سطح اکسیژن در بافت یا هیپوکسی تنظیم می کند. HIF-1 با واسطه در متابولیسم میتوکندری و در نتیجه کاهش استرس اکسیداتیو اثرات محافظتی در برابر هیپوکسی اعمال می کند. اخیراً، افزایش سطح استرس اکسیداتیو و متابولیسم...
  12. Hayley

    Horrible depressive side effects from melatonin

    I just ran out of the melatonin (3 mg) I’ve been taking for 3 months now. I kind of suspected it might be making me sluggish but I kept taking it because I wanted to be knocked out to go to sleep. The past two mornings without taking it the night before I’ve woken up not feeling like a train hit...
  13. haidut

    High (extracellular) serotonin causes Alzheimer's and depression

    The utter corruption of "journalism" is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT -...
  14. K

    I've Never Felt So Alone

    Checking in from Ontario Canada to... rant? Per the title of the thread: I've literally never felt this alone. I'm 25/F, and have been told by my job (online work, small team, not customer facing) if I don't get the vaccine by the end of next month, I'm done. My partner is currently with me in...
  15. Sefton10

    Mainstream book/article links depression and authoritarianism with energy metabolism

    "We often think of depression is a mood disorder, but depression is also metabolic disorder – meaning that, fundamentally, there is something wrong with your metabolism and your energy regulation. When you experience depression, you don’t experience that metabolic difficulty directly; you...
  16. limitless77

    Can SSRIs help someone who is depressed

    I've been following raypeat ideas for some time now and I know that he is against serotonin, but I'm desperate and I've did some research about SSRIs and from my understanding they don't raise the production of serotonin in the body like tryptophan and 5-htp do, but they keep the serotonin...
  17. Drareg

    Children anti-depressants, 231,791 prescriptions UK in 2020

    Western nations are really destroying themselves at this rate, kids at 5 years of age and up getting prescribed SSRI’s, the medical establishment needs to reeled in ASAP. COVID was the excuse used to justify this, it’s driven by profit margins for big pharma, the parents must be stupid, it’s...
  18. G

    I am a tired b****. Please help

    Hello, I have been dealing with feelings of hopelessness, depression, low energy, could stare at a wall for hours, no zest for life, I have become increasingly less nice to people. Been feeling this way for about 6 years now. I am wondering if there are any MEDICATIONS that have helped anyone...
  19. Eastcoast Seth

    What causes narcissism?

    Good Afternoon, After encountering a compulsive, narcissistic liar on this forum, I am wondering: What causes narcissism? Are there hormones involved. I‘d like to hear the „peaty“ view on this. Thank you, my fellow beardy peatarians.
  20. haidut

    AlloP - Liquid Allopregnanolone For Lab/R&D

    Just a quick announcement that we have replaced the 5α-DHP in our store with allopregnanolone. The main reason for switching over to allopregnanolone is that we always wanted to provide that steroid right from the start, however we could not find a lab willing to synthesize it. Thus, 5α-DHP...
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