dementia

  1. raypeatclips

    Calcium Channel Blockade By Magnesium Chloride On Memory. Dementia

    I don't fully understand this one myself, it looks interesting though and have seen calcium channel blockers mentioned before on here. The study concludes that this should be considered when designing treatment for dementia and other memoryproblems. Sex- and dose-dependent effects of post-trial...
  2. haidut

    Alzheimer Disease (AD) May Be Simply Diabetes Of The Brain

    I touched upon this topic in one of the Danny Roddy shows we did last year but the evidence since then has continues to accumulate that AD is entirely a metabolic disorders, basically identical to diabetes but focusing on the brain. A recent study found that delirium, an acute form of...
    • haidut
    • Thread
    • ad alzheimer's brain dementia dhea diabetes glucose inhibitor insulin resistance memantine potassium channel
    • Replies: 13
    • Forum: Scientific Studies
  3. haidut

    Delirium (and Dementia/AD) Is Caused By Inability To Oxidize Glucose

    Ray has written about the metabolic origins of Alzheimer disease (AD) and I posted quite a few studies on the links between AD and PUFA metabolites as well as insulin resistance in the brain. I even mentioned on one of Danny Roddy's shows that there is a proposal by NIH to reclassify AD as...
    • haidut
    • Thread
    • ad alzheimer's delirium dementia ffa glucose insulin metabolism niacinamide pufa
    • Replies: 7
    • Forum: Scientific Studies
  4. haidut

    Caffeine Protects Against Dementia (AD), ALS, Parkinson, And Huntington Disease

    The link between caffeine intake and lower risk of neurodegenerative conditions has been established before but the mechanism of action was unknown. This study discovered one possible mechanism and also confirmed the associative findings in vivo using a mouse model. The HED was 150mg - 300mg...
    • haidut
    • Thread
    • als alzheimer's caffeine dementia huntington's nmnat2 parkinson's protective treatment
    • Replies: 12
    • Forum: Scientific Studies
  5. haidut

    Glucose Deprivation In The Brain Is A Causative Factor In Alzheimer's Dieases (AD)

    As the study says, whether lower glucose levels in the brain were the consequence or cause of AD was considered unknown until recently. This is one of the studies that established a causal link between lower blood glucose levels in the brain and the development AD. I wonder if we are going to...
    • haidut
    • Thread
    • alzheimer's dementia deprivation diabetes fructose glucose sucrose
    • Replies: 52
    • Forum: Scientific Studies
  6. P

    Brain Insulin Resistance Identified As Possible New Link Between Alzheimer's Disease, Diabetes

    It says brains inability to burn glucose is responsible for Alzheimer's disease.caused by insulin's resistance in brain, and that probably mediated by inflammation. Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease – PR News...
  7. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
    • haidut
    • Thread
    • 5α-dhp 5α-dihydroprogesterone alzheimer's antidepressant antiestrogen brain cns dementia gaba glycine ms neurosteroid parkinson's protective
    • Replies: 25
    • Forum: Scientific Studies
  8. haidut

    Being Obese / Overweight Protects Against Dementia In The Elderly

    Another example of the "obesity paradox", this time the authors themselves call the extra weight being protective and it was not something deduced by the public by reading the study. Dramatic decline in dementia seen among older adults in the US "...One possible factor is education. The older...
    • haidut
    • Thread
    • cvd dementia elderly obesity overweight paradox protective study
    • Replies: 35
    • Forum: Scientific Studies
  9. haidut

    Carbonic Anhydrase Is A Key Driver Of Aging; Inhibiting It Is Beneficial

    In support of Ray's views of CO2 as one of the main factors in mitochondrial biogenesis and health, and as such in a host of health conditions, this study found that carbonic anhydrase levels are higher and the enzyme itself is more active in both aging and degenerative conditions. Inhibiting...
    • haidut
    • Thread
    • acetazolamide aging antiaging brain cancer carbonic anhydrase carbonic anhydrase inhibitor co2 dementia neurodegeneration pathological thiamine vitamin b7
    • Replies: 39
    • Forum: Scientific Studies
  10. haidut

    Estrogen Or Anti-androgen Therapy Shrinks Brain And Destroys Grey Matter

    This was a human study and one of the very few to look at steroid effects on the brain as a result of supplementation. As the study said, the results are very relevant for all women who take birth control pills or HRT. It even says that estrogen therapy is known to cause dementia later in life...
    • haidut
    • Thread
    • anti-androgen treatment brain brain shrinking decrease dementia estrogen hormone replacement therapy study volume
    • Replies: 3
    • Forum: Scientific Studies
  11. haidut

    Testosterone Deprivation For Prostate Cancer Causes Dementia / Alzheimer

    Not surprising at all, and very common these days. Take one drug or treatment approach and not only you don't get any actual cure but you also get another nasty condition as a side effect. The barbaric treatment of prostate cancer (castration) is now officially known to lead to dementia in the...
    • haidut
    • Thread
    • adt alzheimer's androgen deprivation castration dementia prostate cancer
    • Replies: 3
    • Forum: Cancer
  12. haidut

    Methylene Blue Improves Short-term Memory In Humans

    I suppose the results of this study are to be expected but I wanted to post it anyways since it was one of the few human studies using methylene blue. The doses used was pretty high (4mg/kg for human) but for some reason the authors claim that this is actually a pretty low dose. Be that as it...
  13. haidut

    Pregnenolone May Protect Cognition From Damage By Stress

    The study was actually on how stress damages cognition, and based on another study I posted and the drug used in the study to block the effects of stress I inferred that pregnenolone would work just as well. The study discovered that the release of CRF / CRH as part of the stress response is...
    • haidut
    • Thread
    • cognition crf crh dementia depression pregnenolone schizophrenia stress
    • Replies: 2
    • Forum: Scientific Studies
  14. haidut

    Dementia Breakthrough - Alzheimer Disease Linked To Endotoxin And Iron

    Nice to see medicine may be finally making a 180-degree turn but I would not hold my breath for it to become mainstream treatment any time soon. Given the abilities of aspirin to chelate iron directly from the brain, this may be one of the reasons for its beneficial effects on Alzheimer's...
  15. haidut

    Anti-acid Drugs (ppi) May Cause Dementia

    The so-called Proton Pump Inhibitors (PPI) are second generation anti-acid drugs that replaced the much safer first generation H2 antagonists like fomotidine, ranitidine, cimetidine, etc. The PPIs are really bad drugs that should have never been approved considering that they provably cause...
  16. D

    Dementia - How To Cure

    I thought I'd start a post on dementia, to get some feedback on this important topic. Mainstream medicine considers dementia incurable. However, Peat and other people I have read on the internet provide encouraging anecdotes of people coming totally out of dementia, to lead normal and...
  17. Mr Rossi

    Methylene Blue In Treatment Of Cancer, Aging & Dementia - Bernd Friedlander

    • Mr Rossi
    • Thread
    • aging cancer dementia methylene blue pharmaceutical drugs
    • Replies: 5
    • Forum: Methylene Blue
  18. M

    Methylene Blue In Treatment Of Cancer, Aging & Dementia - Video By Friend Of Ray Peat

    Hello, I found a great video that has great information: Methylene Blue in Treatment of Cancer, Aging & Dementia - Bernd Friedlander (Feb 2015) Dr. Friedlander mentions how important Ray’s work has been to him and he mentioned Ray’s genius right from the start and goes right through the...
    • mas
    • Thread
    • cancer dementia methylene blue pharmaceutical drugs
    • Replies: 7
    • Forum: Methylene Blue
  19. haidut

    Being fat in middle age protects against dementia and AD

    Another study that matches Ray's statements that it is less harmful to be overweight (and even obese) than to be in the "healthy" spectrum of the BMI that is currently being promoted as the main prevention for all diseases. One feature of obese and overweight people is that they retain much more...
  20. S

    Low Sodium And Dementia

    [Hyponatremia, cause of reversible dementia in the elderly].
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