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Ray has written about the metabolic origins of Alzheimer disease (AD) and I posted quite a few studies on the links between AD and PUFA metabolites as well as insulin resistance in the brain. I even mentioned on one of Danny Roddy's shows that there is a proposal by NIH to reclassify AD as...
The symptoms of alcohol withdrawal and its associated delirium are due mostly to serotonin overload and functional GABA deficiency. As such, anti-serotonin drugs can be very beneficial but they often have side effects and cannot be freely obtained. This human study showed that a single...
I have several friends who are ER physicians and one of them works in the ICU as well. The topic of post-surgical delirium has come up many times and all of them vehemently denied that serotonin has anything to do with it. The current view is that the mechanism and cause is unknown and heredity...
The study was done on old surgical patients but I don't see why it would not apply to everybody. Post-surgical delirium is a very big issue in surgical wards these days and there are no reliable ways to prevent/treat it. This study found that elevated CRP is the best predictor of delirium...