cvd

  1. haidut

    Androgen Deficiency As The Main Cause Of Chronic Disease In Males

    This is one of the most comprehensive reviews that I have ever come across on the topic of androgens and their role in male health. It is authored by one of the most renowned experts in urology - the former director of the Department of Urology at Boston University (BU) School of Medicine. Given...
  2. haidut

    Endotoxin (LPS) Theory Of Atherosclerosis (CVD)

    I posted a study more than year ago, which examined the role of NO in aging and disease. The Nitric Oxide (NO) Theory Of Aging One of the main endogenous stimulators of NO synthesis is endotoxin (LPS). It turns out that the connection between LPS and CVD has been studied for a long time in...
  3. haidut

    Americans Are Retiring Later, Dying Sicker And Sooner In-between

    The mainstream media is finally starting to seize onto the facts that the common population has been observed "anecdotally" for over 20 years. That is, the health of the average American has been steadily deteriorating, while life has become progressively harder (financially) for most working...
  4. haidut

    High Levels Of (endurance) Physical Activity Increase Risk Of CVD

    The study compared levels of physical activity (most often "endurance" exercise) and found that those in the highest titre have much higher risk of CVD compared to moderate or light activity. In light of the recent threads that starting and then stopping "endurance" exercise can make a person...
  5. haidut

    Cortisol And Aldosterone Cause Vascular Calcification

    In one of his newsletter circa 2015, Ray wrote about the role of aldosterone in heart failure, heart attacks, shock, and edema. He conjectured that aldosterone antagonists would one day be recognized as therapeutic for these conditions. Almost all types of heart disease start with vascular...
  6. haidut

    Standing At Work May Be A Lot More Dangerous Than Sitting

    I am sure many people here have seen the flood of ads for "standing desks" - a raised desk without a chair which a person uses to work in an upright position instead of sitting. Thee have been many health claims made for these desks, none of which have been verified so far in controlled studies...
  7. haidut

    Grey Hair May Be A Biomarker For CVD (and Biological Age) In Men

    Ray has written about the role of low copper, high serotonin, and generally low thyroid function in changing hair color from dark (or blonde) into white with advancing age. It just so happens, that these phenomena also affect heart health. I have long suspected that premature greying of hair on...
  8. haidut

    CNN: Saturated Fat Does NOT Clog Your Arteries; Stress And Inflammation Do

    I think we will be seeing more and more of these "breaking news" on major news outlets as the house of cards made of PUFA slowly crumbles. The FDA already reversed its official recommendations on cholesterol, but left the policies on saturated fat intact even though the same study on which the...
  9. haidut

    Supplementary Choline Raises Risk Of Blood Clots; Aspirin To The Rescue

    Ray has written about the dangers of choline and its close relationship with estrogen. The histamine and acetylcholine receptors are perhaps the two main systems through which estrogen negatively affects the systemic health of the organism. As such, antihistamine and antocholinergic drugs can...
  10. haidut

    Pharma Companies Lie About Drug Benefits And Hide Side Effects

    Not that this is anything new, but one of the shocking findings of the study is that officially prescribed, approved drugs are the 3rd leading cause of death in UK, after cancer and CVD. But given that many of the cancer and CVD cases may very well be caused by these same drugs, the scary truth...
  11. haidut

    Another "obesity Paradox" - It Lowers Mortality In Patients With Atrial Fibrillation

    I hope this is not taken as a call to get obese. I am posting it simply as an example that obesity may be a protective mechanism once a disease is already established. As such, it should not be viewed always in a negative light but as a possible result of an endocrine disorder, which likely...
  12. haidut

    Solid Evidence That Stress Causes Obesity

    The statement in the title should be fairly obvious for most forum members or people following Peat's work. In fact, most endocrinologists are keenly aware of the role of stress and cortisol in causing obesity, metabolic syndrome and diabetes. However, believe it or not, officially the FDA and...
  13. haidut

    Strong Androgens (DHT) As Treatment For CVD, Obesity And Metabolic Syndrome

    The study used DHT as the active drug but since the positive effects were due to androgen receptor agonism, any other strong androgen agonist should do. I think the lack of estrogenicity also contributed to the benefits of DHT observed in this study, so this would explain the mixed results with...
  14. Constatine

    Vitamin K2 Protective Against Pufa

    Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes. - PubMed - NCBI BACKGROUND: Positive associations have been observed between cardiovascular disease (CVD) and type 2 diabetes mellitus (DM), but their causal relationship has not been clarified. Nevertheless...
  15. haidut

    Removal Of Ovaries Increase Risk Of CVD, Cancer, And Premature Death

    It has become very customary in recent years to advise post-menopausal women or even with preproductive age to undergo ovariectomy if there is evidence of cysts, fibrosis, or other issues that the doctors think could predispose the woman to developing ovarian cancer later on. As usual, there is...
  16. haidut

    Androgens (androsterone/DHEA/T) Are Calcium Channel Blockers / Antagonists

    The study found that all tested androgens, as well as progesterone were calcium channel blockers and 5b-DHT was the most potent. Androsterons was next, and it was equipotent to DHEA and testosterone. While the dose used in the study was high, the authors believe that the same effects may be...
  17. haidut

    Pregnenolone (and DHEA) May Protect From Heart Disease

    In some of his recent emails to people Ray recommended pregnenolone as a substance that lowers prostaglandins and inflammation. This mechanism of action also happens to be the officially proposed one for the benefits in heart disease seen with aspirin use. I was looking for the studies to...
  18. haidut

    Glycine May Protect From Heart Disease In Women

    The study looked at carriers of a specific variant of the gene CPS1 and the control this gene exerts over specific metabolites. Carriers of this gene variant had significantly increased glycine levels in the blood and lower levels of urea cycle metabolites, especially citrulline (which is a...
  19. haidut

    The Benefits Of Aspirin Outweigh The Bleeding Risks

    I posted a few studied in the past showing that instead of increasing bleeding in the brain and GI tract, aspirin protected from these very events, especially in people with life-threatening levels of bleeding. GI Bleeding Risks Of Aspirin Are Grossly Overstated Aspirin Actually Lowers Risk Of...
  20. haidut

    Depression Affects The Digestive System Health, Anxiety The Skin

    Ray has written quite extensively on the connection between intestinal inflammation and both mental disorders as well as skin health. There is a quote from him often appearing on the front page saying something along the lines that the health of the intestine is reflected in the physiology of...
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