cox

Just in case there are still doubts out there about just how detrimental PUFA is to our health, here is a study showing that just one of PUFA's "normal" metabolites (i.e. enzymatically derived, instead of through peroxidation) is sufficient to elevate lipolysis, and that effect alone is enough...

The link between NSAID usage (except aspirin) and heart attacks is not new, but I decided to still post this study due to the fact that it is the first to suggest those non-aspirin NSAID may actually damage the heart themselves rather than cause CVD events indirectly. Notably, once again...

While most of medicine's attention is focused on acute pancreatitis (AP) since AP is often deadly, rates of chronic pancreatitis (CP) have been rising over the last 2-3 decades and it is now recognized that CP is a "gateway" condition to either liver or pancreatic cancers. Officially, CP has no...

An epidemiological study, yet still useful IMO since the correlation was maintained across the various levels of PUFA intake - i.e. the higher the PUFA intake the higher the prevalence of a mental disorder such as depression, which suggests a causal link. The link was the strongest in males and...

A great study, albeit in-vitro, that once again throws into doubt the entire hypothesis behind prostate cancer. First, it proves the key role of PUFA in the genesis and progression of prostate cancer by demonstrating that inhibitors of the COX enzyme (responsible for synthesizing prostaglandins...

Cyclooxygenase-2 Regulation of the Age-Related Decline in Testosterone Biosynthesis | Endocrinology | Oxford Academic ...The age-related decline in testosterone biosynthesis in testicular Leydig cells has been well documented, but the mechanisms involved in the decline are not clear. Recent...

The link between sunlight exposure and incidence of MS is well-known and strongly pointed to a metabolic origin of the disease as early as the 1960s. It led to a few underpowered trials with low dose vitamin D, which did not find much benefit. However, a recent trial with a higher dose (10,000...

I don't think the findings of this study will come as a surprise to forum members but I think it is important to post it here as it is one of the few studies that points directly the finger at PUFA and calls it out by name. It is also the first study I have seen stating that reducing PUFA...

Just wanted to post here as diabetes is perhaps the most common chronic disease in the world and many diabetes sufferers have kidney disease, which is considered irreversible. However, as this clinical trial states (and as Peat said as well), the kidney damage seems to be due to inflammation...

Ray has written so much of the effects of stress on health and specifically on how chronic stress promotes energetic dysfunction and tumor formation/growth/spread. However, up until a year ago there was very little "official" research to back up his views. This study does just that, and it shows...