cortisol

  1. S

    Propranolol And Hair Loss

    If propranolol reduces cortisol, adrenaline and has bone protective effects (opposite to calcification?) Would it be a potential remedy for hair loss?
  2. ddjd

    Dopamine = Very Male Energy. Cortisol/serotonin = Female

    I know some people will say I'm reading too much into this, but after years of experimentation with different supplements, I can say for certainty that those supplements that have strong dopamine raising effects make me much more amiable to other men and actually make me very unattractive to...
  3. haidut

    Stress (cortisol) Can Cause ANY Autoimmune Condition By Disrupting Gut Barrier

    A great new study that is not afraid to point out the paradox between mainstream medicine's claims of beneficial effects of cortisol and the reality of "autoimmune" conditions more often than not being associated with elevated levels of CRH, ACTH and cortisol. The role of CRH as a causative...
  4. haidut

    Cortisol Drives Triple-negative Breast Cancer, Androgens (DHT) Are Therapeutic

    Another confirmation of a hypothesis made more than 100 years ago - i.e. all cancers are hormonally sensitive and to speak of a steroid-negative cancer is nonsense. If all cancers are driven by at least one steroid then it would make sense to discover what that steroid is and develop therapeutic...
  5. haidut

    Aspirin/salt For Treating A Broken Heart, And What REALLY Causes Afib

    At a first glance the study below seems rather mundane but a careful read provides some very interesting insights. The syndrome of "broken heart" is a real physiological condition that medicine has tried to deny for decades despite even assigning it its own official medical name - Takotsubo...
  6. haidut

    The Keto Diet Works Only For A Week, Then It Causes Obesity And Diabetes

    A great study that goes a long way towards dispelling the currently dominant dietary fad - the keto diet, as well as various other functionally equivalent diets such as Paleo, Warrior, intermittent fasting, etc. As the study unequivocally demonstrates, the reductions in blood sugar and weight...
  7. haidut

    How Chronic Stress (cortisol) Causes Disease

    Back in 2018 I did a post on a neat study that demonstrated how the presence of cellular (mitochondrial) fragments in the blood stream acts identically to the pituitary hormone ACTH and as such activates the HPA axis. The more cellular fragments are in the bloodstream the more intense the stress...
  8. haidut

    Male Fertility Depends On Intensity Of (sperm) Metabolism

    Yet another aspect of health that turns out to be directly controlled by quality/speed of metabolism. I made a few posts in the past demonstrating that progesterone and pregnenolone activate a calcium channel (CatSper) specific to progesterone, which greatly increases sperm motility...
  9. haidut

    Burning More Fat And Less Glucose Leads To Diabetes

    I really hope the keto community and other low-carb diet afficionados are taking note of the stream of recent studies that keep demonstrating a causative link between low-carb and/or high-fat diets, fasting, chronic stress, cortisol and diabetes. The evidence at this point is indisputable, no...
  10. haidut

    Chronic Stress (adversity) Lowers Dopamine And Causes Mental Illness

    The evidence for the role of chronic stress in virtually every health condition doctors have a name for just keeps on accumulating. Unfortunately, even in this latest study the scientists keep insisting that there is some mysterious and unquantifiable difference between chronic stress...
  11. haidut

    Estrogen And Cortisol, Not Androgens, Suppress Immunity

    There is a very famous theory in reproductive biology still considered the dominant one in its field. Namely, males have to accept a trade-off between androgen levels and immunity. It is known as the immunocompetence handicap hypothesis (ICHH). Higher androgen levels, the theory goes, allow the...
  12. haidut

    Rats Can Drive Cars (to Lower Stress), Befriend Robot Rats And Help Them When In Trouble

    Official/pathological science keeps sternly warning us not to anthropomorphize and to think of animals as nothing but dumb, soul-less automatons. Yet, there has been no evidence discovered in over 100 years of pathological science reign to support such a view. To the contrary, the studies below...
  13. Adrenaline

    Interesting Facts About Cyproterone (Hair Loss)

    Cyproterone Acetate is an anti-androgen drug used for transitioning, hair loss, acne, hirsutism and so-called androgenic disorders. But when I search PubMed I found interesting mechanisms about this drug. * First of all it strongly decreases cortisol and aldosterone and increases DHEA levels...
  14. haidut

    Poverty Makes People Dumb And Prematurely Old

    A common debate in public policy is whether people slide into poverty because they are stupid or being poor makes people stupid and unable to cope with life. The study below adds some evidence to the latter claim and found that extended poverty (20 years or longer) exposure also causes premature...
  15. Tristan Loscha

    Study:Normal To High NaCl Intake Is Associated WithPsoriasis, CNS-Disorders,IL17

    These Data-Hamsters are unhinged,let them entertain us though.Allegedly excess NaCl and concomitant rise of Sodium sensing Glucocorticoid-Kinase1,Interleukine liberation,NFKB induction etc, is a major driver of inflammation. Link To Full...
  16. Mito

    Glucose And Lipid Homeostasis And Inflammation In Humans Following An Isocaloric Ketogenic Diet

    Objective The objective of this study was to measure changes in glucose, lipid, and inflammation parameters after transitioning from a baseline diet (BD) to an isocaloric ketogenic diet (KD). Methods Glucose homeostasis, lipid homeostasis, and inflammation were studied in 17 men (BMI...
  17. haidut

    High Cortisol And Low Testosterone Likely Drive PTSD

    As the article below states, 20%+ of service members come back with PTSD. It is a devastating mental condition that makes patients not only unable to participate meaningfully in society but often drives them to violent and homicidal/suicidal behavior. Given the roles of cortisol and serotonin in...
  18. haidut

    Cheating Is Driven By Cortisol, Not Testosterone

    The topic of macho behavior and its apparent mediator testosterone has been studies every since steroids were discovered. The mainstream dogma states that high testosterone drives cheating behavior (especially of males) as some sort of dominance-asserting behavior of genetically superior...
  19. haidut

    Cortisol (stress) Directly Causes Depression

    I have posted quite a few threads/posts on the role of stress as perhaps the main cause of depression and other mental disorders. Officially, psychiatry claims that no environmental factor is known to be a direct cause of depression and that depression is a “complex” mix of genetic...
  20. ecstatichamster

    Cortisol Lowers TSH - Can Make Hypo Thyroid Person Seem "normal"

    Thyrotropin Levels during Hydrocortisone Infusions That Mimic Fasting-Induced Cortisol Elevations: A Clinical Research Center Study 1 Both short term fasting and administration of high doses of glucocorticoids lead to marked suppression of serum TSH levels in healthy subjects. However, it is...
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