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cocaine
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Pregnenolone (P5) blocks stress-induced anxiety, hypertension and cocaine cravings
A great new study, and with humans too! As the study aptly demonstrates, the primary driver of cocaine cravings is likely stress and the anxiety it causes. This finding is another corroboration of the findings of the great Rat Park experiment/study on "addiction". In the study below, the...- haidut
- Thread
- addiction anxiety cocaine cvd hypertension p5 pregnenolone stress
- Replies: 16
- Forum: Scientific Studies
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Gut bacteria overgrowth drives (cocaine) addiction; glycine can reverse it
Yet another study highlighting the importance of the microbiome for our health, and suggesting again that there may be no such thing as truly beneficial bacteria. Any bacteria capable of colonizing our GI tract seems to be capable of causing pathology if it is allowed to proliferate without...- haidut
- Thread
- addiction antibiotics brain cocaine gelatin glycine gut microbiome
- Replies: 18
- Forum: Scientific Studies
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Estrogen promotes, progesterone inhibits drug (cocaine) abuse
An interesting study, which not only exposes yet another negative side of estrogen but also demonstrates the opposing actions estrogen and progesterone have on the brain. The former is excitatory (by activating the glutamate system and inhibiting the GABA system) while the latter does the exact...- haidut
- Thread
- addiction cocaine drugs estrogen gaba glutamate progesterone
- Replies: 8
- Forum: Scientific Studies
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Cocaine "addiction" May Be Driven By Serotonin
Another study on addiction and its mechanisms, but this one focuses on cocaine which is the second most highly abused drug after alcohol, at least in the US (excluding weed). This new study shows that blocking the serotonin receptor 7 (5-HT7) blocked the cocaine abuse behavior. This would...- haidut
- Thread
- 5-ht7 abuse addiction antibiotics charcoal cocaine cyproheptadine metergoline serotonin
- Replies: 2
- Forum: Scientific Studies