co2

  1. DeadCatBounce

    Rectal CO2 with carbonated water enema ? Experiment

    A bit weird thread and experiment. Been having hair shedding issue last few days due to a DHEA experiment for which I posted a separate thread. Yesterday decided to carbonate some purified water with my sodastream and use it on the scalp to see if it helps. While I was pouring the carbonated...
  2. haidut

    Low-dose niacinamide has striking anti-obesity effects

    It looks like the medical world has firmly set its sights on the bioenergetic wave/target, as the number of scientific papers focusing on niacinamide, NAD/NADH ratio and OXPHOS in general has been steadily climbing since 2010. That would be good news, despite the attempts of companies such as...
  3. haidut

    Hypogonadism in older males due to low OXPHOS

    I suspect many readers will simply say "duh!", but believe or not the origin of age-related hypogonadism in males is still considered unknown. Most endocrinologists have discovered experimentally that treating their patients with SERM or AI drugs restores androgens to youthful levels, but the...
  4. JamesGatz

    Awaken your breathing - Guided breathing exercises and meditations to boost metabolism, reduce stress, and expand our bones

    This will be a thread dedicated to breathing correctly and to awaken our breathing systems - respiration/breathing are extremely important to metabolic health and is definitely a field that I believe this many on the forum will benefit from ***** Full Credit to The Great Work/Kharna Dharma and...
  5. tastyfood

    Gerolsteiner now $2.69 at Whole Foods. WTF. Up from $2 in the last 8 months.

    Getting additional minerals and carbonation from water will keep costing you more and more if the trend continues. I used to get a bottle of Gerolsteiner carbonated mineral water for $2 at Whole Foods in the US. A bit cheaper at Trader Joe's. A while ago it went up to about $2.20. Now it's...
  6. A

    Aspirin could act as a suicide inhibitor of carbonic anhydrase II

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226357/ Abstract Carbonic anhydrase II (CAII) is a metalloenzyme that catalyzes the reversible hydration/dehydration of CO2/HCO3−. In addition, CAII is attributed to other catalytic reactions, including esterase activity. Aspirin (acetyl-salicylic...
  7. ecstatichamster

    Anyone have good CO2 tank, bag resources and experience

    I bought a CO2 tank but it’s not with me. Do you have experience and sources for the big body bag, tank etc.? Dr. Peat’s discussions on Radio One have gotten me re-interested in this. CO2 has been the greatest thing for me so far, ever.
  8. A

    Hypoxic chambers may cause myocardial repair after a heart attack

    Abstract Background: Oxygen supplementation in myocardial infarction (MI) remains controversial. Inflammation is widely believed to play a central role in myocardial repair. A better understanding of these processes may lead to the design of novel strategies complementary to MI treatment...
  9. md_a

    Ray Peat Interview Dr. Ray Peat, Ph.D – Your Health Questions Answered – February 21, 2022

    https://oneradionetwork.com/all-shows/dr-ray-peat-ph-d-your-health-questions-answered-february-21-2022/
  10. Mauritio

    Gates, Musk and Oxford want to remove CO2 from the atmosphere - big time.

    "Microsoft Corp. founder Bill Gates and Tesla Inc.'s Elon Musk do not agree on much but both are writing large checks to support carbon removal." I think they will do something big to get rid of CO2 in the air. It's not enough for them to make the corporations pay for it (carbon credits)...
  11. A

    Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection?

    The ongoing Covid-19 is a contagious disease, and it is characterised by different symptoms such as fever, cough, and shortness of breath. Rising concerns about Covid-19 have severely affected the healthcare system in all countries as the Covid-19 outbreak has developed at a rapid rate all...
  12. A

    Elevated CO2 Levels Delay Skeletal Muscle Repair by Increasing Fatty Acid Oxidation

    Muscle dysfunction often occurs in patients with chronic obstructive pulmonary diseases (COPD) and affects ventilatory and non-ventilatory skeletal muscles. We have previously reported that hypercapnia (elevated CO2 levels) causes muscle atrophy through the activation of the AMPKα2-FoxO3a-MuRF1...
  13. A

    Elevating the level of hypoxia inducible factor may be a new potential target for the treatment of depression

    فاکتور 1 القایی هیپوکسی (HIF-1) یک فاکتور رونویسی است که بیان ژن را در پاسخ به کاهش سطح اکسیژن در بافت یا هیپوکسی تنظیم می کند. HIF-1 با واسطه در متابولیسم میتوکندری و در نتیجه کاهش استرس اکسیداتیو اثرات محافظتی در برابر هیپوکسی اعمال می کند. اخیراً، افزایش سطح استرس اکسیداتیو و متابولیسم...
  14. Hans

    CO2 might be the stronger and safest anti-inflammatory agent against RONA

    https://pubmed.ncbi.nlm.nih.gov/34741187/ "Mitogen-activated protein kinase (MAPK) signalling pathways are crucial for developmental processes, oncogenesis, and inflammation, including the production of proinflammatory cytokines caused by reactive oxygen species and upon severe acute respiratory...
  15. A

    Intermittent hypoxia training as non-pharmacologic therapy for cardiovascular diseases: Practical analysis on methods and equipment

    The global industrialization has brought profound lifestyle changes and environmental pollutions leading to higher risks of cardiovascular diseases. Such tremendous challenges outweigh the benefits of major advances in pharmacotherapies (such as statins, antihypertensive, antithrombotic drugs)...
  16. A

    Hypercapnia-inducible factor: a hypothesis | Aging and longevity

    Abstract Cells and tissues sense and respond to hypercapnia by global activation or down-regulation of hundreds of genes and switching on/off a number of signaling and metabolic pathways. We hypothesize for the first time that such complex rearrangements are hardly possible without subtle...
  17. S

    CO2 Bag Bath Experience

    Been wanting to play around with CO2 for awhile now and finally got the inspiration to go out and get everything needed. Here's what I did followed by my experience: Warning: You can suffocate and die, please go slowly, make sure someone is around, and always empty the bag of CO2 after your...
  18. JamesGatz

    What are the best plants to have in your home ? Is there a benefit to having Christmas trees in your backyard that you can spend time around ?

    One of my neighbors has these evergreen trees all over her front yard (they have a very clean Christmas Tree smell that you smell when you buy evergreens - I notice that when I am near her house around her trees - The air feels significantly cleaner and I feel a noticeable metabolic boost - I...
  19. JamesGatz

    How cruel is the practice of limb amputation ? Below-knee amputations effect on lifespan and hospitals causing this issue ?

    I was looking at this story of Nick Cordero who died of "covid" after he had his leg amputated by the hospital because : https://www.cnn.com/2020/04/19/entertainment/nick-cordero-coronavirus-leg-amputation-trnd/index.html Saturday was day 18 of him being sedated in the intensive care unit...
  20. A

    Metabolic remodelling of mice by hypoxic (decreased O2)-hypercapnic (increased CO2) environment

    We hypothesised that hypoxic-hypercapnic environment (HHE) could induce metabolic suppression and associated benefits for health and longevity, as observed in the naked-mole rat (NMR). We developed a model of self-produced HHE (similar to a natural habitat of NMRs), which is simple, reliable and...
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