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cholecalciferol

  1. haidut

    Low vitamin D and HIGH (not low) PTH predict bone deterioration

    A great new study, which would hopefully trigger a re-assessment of the current approaches in treating osteoporosis/osteopenia. Namely, one of the core therapies for deteriorating bone health/density (usually associated with aging, glucocorticoid treatment, kidney disease, etc) is administration...
  2. haidut

    Vitamin D likely effective as an antidepressant

    That is the simple conclusion of the largest meta-study to date. Namely, vitamin D in doses above 2,000 IU daily has antidepressant effect when used as monotherapy. The antidepressant effects of vitamin D when used in combination with pharma antidepressant drugs is already well-established, so...
  3. haidut

    Vitamin D Deficiency Can Lead to Dementia And Stroke

    Despite this being an observational study, the analysis for extraneous factors has been strong enough that the authors believe the link between vitamin D deficiency and dementia/stroke is causal. As the study itself says, almost 20% of dementia/stroke cases could be prevented by simply...
  4. haidut

    Vitamin D can prevent, and even reverse, the cancerization process

    The study is on ovarian cancer but I don't see why its findings won't apply to all other cancers, as the study itself states, especially the ones forming in the abdominal cavity and involving the peritoneum. he study found that vitamin D can actually restore the "cancer" cells back to normal...
  5. haidut

    Milk or water are optimal drinks for (oral) vitamin D bioavailability

    Just a quick post about something I thought many people will probably find interesting, considering the widespread use of oral vitamin D supplements. The findings of the study are a bit surprising, considering that vitamin D is one of the "fat-soluble" vitamins and as such is expected to be...
  6. haidut

    High-dose vitamin D could help fight HIV/AIDS

    Actual article title, though I disagree with the "high-dose" qualifier as it corresponds roughly to a vitamin D3 dose of ~7,000 IU daily, which is not really a pharmacological dose. While the authors were not brave enough to claim that vitamin D supplementation could be an effective prophylactic...
  7. haidut

    Vitamin D2 (ergocalciferol), unlike D3 (cholecalciferol), ineffective for immune health

    A very important study, with huge ramifications, considering most people taking prescription vitamin D are consuming vitamin D2 (ergocalciferol) as that is the only FDA-approved vitamin D variety available for oral use. The widely available OTC variety vitamin D3 (cholecalciferol) is not...
  8. haidut

    Vitamin D effective in humans for preventing autoimmune diseases

    A human study, one of the largest ever conducted, and covering virtually all major autoimmune conditions. Also, the study claims that this is the first intervention trial that looked at effects of vitamin D on developing autoimmune conditions, so the link is causal - i.e. we can now claim that...
  9. haidut

    Muscles starve/waste in the absence of vitamin D

    As turns out, yet again, vitamin D is far from being the simple "bone vitamin" as most TV/online commercials would have us believe. It is actually a (seco)steroid and has already been implicated in a host of metabolic and immune process affecting virtually every disease. Recently, I posted a few...
  10. haidut

    Oral vitamin D3 may treat steroid-driven hair loss

    A very interesting study, which demonstrates that a relatively low (5,000 IU) oral daily dose of vitamin D3 for 6 months, may be able to treat gender-specific (driven by steroids) hair loss. Now, the study participants were all female, with female-pattern hair loss (FPHL), however the findings...
  11. haidut

    Vitamin D may prevent/delay Type I diabetes

    Vitamin D seems to be trying to take aspirin's crown as a universal drug away. The study below is the latest evidence that this remarkable nutrient may have therapeutic effects in conditions that most doctors consider completely unrelated outside of vitamin D's realm (e.g. calcium absorption)...
  12. haidut

    Vitamin D3 anabolic, calcitriol catabolic for muscle/thymus

    Several great studies, which will probably do little to calm down the controversy that seems to be brewing lately in the blogosphere over whether supplementing with vitamin D3 is beneficial or not. Namely, the last study below demonstrated direct muscle-anabolic effects from supplementation with...
  13. haidut

    Vitamins D and E - the Taliban in the COVID-19 war

    Despite the massive censorship all over the Internet, there have been plenty of articles and studies on vitamin D and its role in COVID-19. Several studies reported that at least 9 in 10 of hospitalized patients have severe vitamin D deficiency. In addition, a few small studies demonstrated that...
  14. haidut

    Vitamin D, reducing fat oxidation may treat lung fibrosis, COVID-19

    Pulmonary fibrosis, regardless of etiology, is considered invariably a progressive and fatal disease. Despite this official story, behind the scenes several pharma companies are running clinical trials with several anti-fibrotic agents and the results so-far demonstrate that the condition is...
  15. haidut

    Avoiding sunlight increases colon cancer risk

    Some time ago I posted about avoiding sunlight being as bad for systemic health as smoking a pack of cigarettes a day. The study below corroborates that view, but with a focus on colon cancer risk and vitamin D. Namely, avoiding sunlight exposure results in much lower vitamin D, which is...
  16. haidut

    High PTH, low vitamin D implicated in bipolar disorder (BD)

    A great study highlighting once again the importance of calcium, vitamin D and especially the pro-inflammatory parathyroid hormone (PTH) for mental health. While there are many studies (both observational and intervention ones) examining the role of vitamin D in mental health, this is one of the...
  17. haidut

    Vitamin D (topical) safe and effective for removing scars

    A neat human study, which demonstrates that topical treatment with vitamin D may treat even large scars that have been present on the skin for years. Many people have such scars as a result of surgery, trauma, chemical/heat burns, radiation, etc. As the study says, the typical treatment is with...
  18. haidut

    Vitamin D deficiency impairs muscles by lowering energy production

    Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition...
  19. haidut

    Vitamin D can force cancer cells to differentiate back into normal

    Danny and I already discussed this topic on a recent podcast, but I decided to post the studies anyways, considering how important the topic is. While progesterone and testosterone are the most well-known differentiating factors in humans, the role of vitamin D has gone largely unnoticed. The...
  20. haidut

    Nine out of ten COVID-19 deaths may be due to vitamin D deficiency

    A remarkable claim in this study, but not really surprising to people who have been studying the vitamin D effects on the immune system. While the study was observational, as the authors explain, the correlation between vitamin D insufficiency and COVID-19 mortality was so high that the authors...
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