cholecalciferol

A great study highlighting once again the importance of calcium, vitamin D and especially the pro-inflammatory parathyroid hormone (PTH) for mental health. While there are many studies (both observational and intervention ones) examining the role of vitamin D in mental health, this is one of the...

A neat human study, which demonstrates that topical treatment with vitamin D may treat even large scars that have been present on the skin for years. Many people have such scars as a result of surgery, trauma, chemical/heat burns, radiation, etc. As the study says, the typical treatment is with...

Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition...

Danny and I already discussed this topic on a recent podcast, but I decided to post the studies anyways, considering how important the topic is. While progesterone and testosterone are the most well-known differentiating factors in humans, the role of vitamin D has gone largely unnoticed. The...

A remarkable claim in this study, but not really surprising to people who have been studying the vitamin D effects on the immune system. While the study was observational, as the authors explain, the correlation between vitamin D insufficiency and COVID-19 mortality was so high that the authors...

A really interesting study, which will likely generate more than a few hateful emails for my Inbox :): Anyways, as the study demonstrates, fasting achieves these negative effects due to the elevated fatty acids working through PPAR activator PGC-1α, to activate both the estrogen receptor (ER)...

A great study for a number of reasons. First, it discussed openly that in animal research circles cortisol administration is considered an official and reliable method of causing major depression. As the article states, for some reason human medical circles have been unwilling to accept the...

In a recent post of mine I discussed the effects of cortisol on various aminotransferases (especially TAT), their role as biomarkers of catabolism, and how inhibitors of said aminotransferases have a potent anti-catabolic / anabolic effects. In that same post, I also described how cortisol (a...

"Effect of Calcifediol Treatment and best Available Therapy versus best Available Therapy on Intensive Care Unit Admission and Mortality Among Patients Hospitalized for COVID-19: A Pilot Randomized Clinical study" Author links open overlay panelMarta EntrenasCastilloaLuis ManuelEntrenas...

Finally Confirmed! Vitamin D Nearly Abolishes ICU Risk in COVID-19 September 3, 2020 The first randomized controlled trial (RCT) of vitamin D in COVID-19 has just been published. The results are astounding: vitamin D nearly abolished the odds of requiring treatment in ICU. Although the number...

It is always good to see proof that medicine has not completely lost its mind by blindly chasing only the latest and greatest discovery in pharma antiviral drugs. The preventive and therapeutic effects of magnesium on viral diseases have been known for decades and has prompted the health...

A very interesting study, not only because of its obvious social implications but also because it confirms the anabolic effects of the vitamin D/K combination, as well as the likely androgenic effects of vitamin D. I could not help but pronounce the D/K combo in my head as "dee-k" :): Another...

A neat study, albeit lasting much longer (about 1.5 years) than most other intervention studied with vitamin D. What makes this study particularly interesting is that it only used high doses vitamin D (60,000 IU once weekly) initially until blood levels rose into the normal range. It did not...

A great new study demonstrating the crucial role of vitamin D in maintaining proper immune function. The study demonstrates that maintaining normal levels of vitamin D is strongly protective against gut infections by Salmonella-type bacteria. Interestingly, the authors claim that vitamin D is...

Despite the ongoing assault against "ineffective" dietary supplements, the evidence in favor of them keeps piling on. One of the favorite targets of mainstream media is vitamin D, and multiple claims of "ineffectiveness" based on "meta" studies have come out in the last 5 years. Usually, this is...

A great study that corroborates my recent post on avoiding sunlight being as bad for health as smoking a pack of cigarettes a day. After all, without sunlight there won't be much vitamin D synthesis and supplementation is not effective for many people due to variety of factors including excess...

As many readers know, there is an epidemic of vitamin D deficiency. It is of worldwide proportions, but is visible mainly in "developed" countries in the Western world. The official stance of mainstream medicine is that while vitamin D deficiency is undesirable, it does not really have much...

Note that the title is the actual opinion of the study authors, and not my interpretation. The study lasted 12 weeks and used 5,000 IU vitamin D3 (cholecalciferol) daily. Beneficial effects on seizures were visible after 6 weeks and were correlated with normalizing vitamin D levels in the...

The study shows that a daily dose of 4,000 IU – 8,000 IU vitamin D reduces cancer progression by up to 36%. The study had 2 phases, the first one used 4,000 IU vitamin D daily and the second one used 8,000 IU daily. Both phases reported robust benefit, and also noted something Peat has been...

The study is not interventional, so too early to say if vitamin D supplementation will help ADHD. However, the link seems promising given the role of vitamin D in dopamine synthesis, which is though to be low in ADHD. [Full text] Vitamin D and vitamin D receptor levels in children with...