cholecalciferol

A really interesting study, which will likely generate more than a few hateful emails for my Inbox :): Anyways, as the study demonstrates, fasting achieves these negative effects due to the elevated fatty acids working through PPAR activator PGC-1α, to activate both the estrogen receptor (ER)...

A great study for a number of reasons. First, it discussed openly that in animal research circles cortisol administration is considered an official and reliable method of causing major depression. As the article states, for some reason human medical circles have been unwilling to accept the...

In a recent post of mine I discussed the effects of cortisol on various aminotransferases (especially TAT), their role as biomarkers of catabolism, and how inhibitors of said aminotransferases have a potent anti-catabolic / anabolic effects. In that same post, I also described how cortisol (a...

"Effect of Calcifediol Treatment and best Available Therapy versus best Available Therapy on Intensive Care Unit Admission and Mortality Among Patients Hospitalized for COVID-19: A Pilot Randomized Clinical study" Author links open overlay panelMarta EntrenasCastilloaLuis ManuelEntrenas...

Finally Confirmed! Vitamin D Nearly Abolishes ICU Risk in COVID-19 September 3, 2020 The first randomized controlled trial (RCT) of vitamin D in COVID-19 has just been published. The results are astounding: vitamin D nearly abolished the odds of requiring treatment in ICU. Although the number...

It is always good to see proof that medicine has not completely lost its mind by blindly chasing only the latest and greatest discovery in pharma antiviral drugs. The preventive and therapeutic effects of magnesium on viral diseases have been known for decades and has prompted the health...

A very interesting study, not only because of its obvious social implications but also because it confirms the anabolic effects of the vitamin D/K combination, as well as the likely androgenic effects of vitamin D. I could not help but pronounce the D/K combo in my head as "dee-k" :): Another...

A neat study, albeit lasting much longer (about 1.5 years) than most other intervention studied with vitamin D. What makes this study particularly interesting is that it only used high doses vitamin D (60,000 IU once weekly) initially until blood levels rose into the normal range. It did not...

A great new study demonstrating the crucial role of vitamin D in maintaining proper immune function. The study demonstrates that maintaining normal levels of vitamin D is strongly protective against gut infections by Salmonella-type bacteria. Interestingly, the authors claim that vitamin D is...

Despite the ongoing assault against "ineffective" dietary supplements, the evidence in favor of them keeps piling on. One of the favorite targets of mainstream media is vitamin D, and multiple claims of "ineffectiveness" based on "meta" studies have come out in the last 5 years. Usually, this is...

A great study that corroborates my recent post on avoiding sunlight being as bad for health as smoking a pack of cigarettes a day. After all, without sunlight there won't be much vitamin D synthesis and supplementation is not effective for many people due to variety of factors including excess...

As many readers know, there is an epidemic of vitamin D deficiency. It is of worldwide proportions, but is visible mainly in "developed" countries in the Western world. The official stance of mainstream medicine is that while vitamin D deficiency is undesirable, it does not really have much...

Note that the title is the actual opinion of the study authors, and not my interpretation. The study lasted 12 weeks and used 5,000 IU vitamin D3 (cholecalciferol) daily. Beneficial effects on seizures were visible after 6 weeks and were correlated with normalizing vitamin D levels in the...

The study shows that a daily dose of 4,000 IU – 8,000 IU vitamin D reduces cancer progression by up to 36%. The study had 2 phases, the first one used 4,000 IU vitamin D daily and the second one used 8,000 IU daily. Both phases reported robust benefit, and also noted something Peat has been...

The study is not interventional, so too early to say if vitamin D supplementation will help ADHD. However, the link seems promising given the role of vitamin D in dopamine synthesis, which is though to be low in ADHD. [Full text] Vitamin D and vitamin D receptor levels in children with...

I rarely stumble across studies like this one. Namely, showing in one single experiment both the detrimental effects of estrogen on one of the most important biomarkers of health (vitamin D), and the beneficial effects of a steroid long vilified/demonized by virtually everybody wearing a white...

As many of you know arterial stiffness is one of the main signs of CVD and contributes significantly to both elevations of blood pressure (BP) and actual ischemic events in brain/heart. According to official guidelines, arterial stiffness cannot be reversed once it sets in, and the only recourse...

Just like the other vitamin products we have released, this product does not really need any introduction to anybody familiar with Peat's work. So, unlike other products of ours, there won't be as many references listed in support of this product but I think even the few ones below are enough to...

The so-called "glucocorticoid resistance" is thought be behind a number of degenerative conditions including diabetes, depression, schizophrenia, chronic inflammation, autoimmune conditions, etc. The condition, similar to insulin resistance, is characterized by elevated serum cortisol levels and...

This is one of the rare human studies using direct intervention for autism. As you can see, there was significant improvement in symptoms with a dose of 300 IU / kg of bodyweight, given daily for 4 months. In addition to the pro-metabolic effects of vitamin D, it is also a known inhibitor of TPH...