caloric restriction

  1. haidut

    Obesity is estrogen-driven; Chronic fasting burns mostly muscle, not fat

    I wanted to do a quick post on this, as this topic is one of the most discussed in both medicine and society in general. Namely, whether fasting is a good and healthy approach to weight loss, which is largely determined by whether the weight we lose during fasting is mostly fat or muscle. Even...
    • haidut
    • Thread
    • caloric restriction estrogen fasting fat metabolism muscle obesity stress
    • Replies: 80
    • Forum: Scientific Studies
  2. haidut

    Aspirin may replicate the benefits of fasting, while avoiding its risks

    I just made a post about fasting raising risk of early death by about 30%. On the other hand, fasting has been shown to lower biomarkers of inflammation as well as increase autophagy, with at least the former being undeniably beneficial. We already know from other studies that the benefits of...
    • haidut
    • Thread
    • aspirin autophagy caloric restriction fasting lifespan longevity mimetic
    • Replies: 11
    • Forum: Scientific Studies
  3. Limon9

    Cognitive Benefits Of Caloric Restriction Are Due To Reduced Tryptophan/Serotonin/mTOR Signalling

    It seems that consuming pure egg white will indeed make you stupid enough to consume pure egg white. Key Points - Calorie restriction improves mental test performance in mice. - Adding tryptophan into calorie-restricted diet abolished memory benefits. - Giving C.R. mice the serotonergic drug...
    • Limon9
    • Thread
    • caloric restriction cognition mtor rapamycin serotonin study tryptophan
    • Replies: 1
    • Forum: Scientific Studies
  4. haidut

    Fasting decreases androgens, increases aldosterone (and possibly cortisol/estrogens) in women

    I often get criticized that I rely too much on animal studies, so here is a human one that should give the proponents of caloric restriction / fasting a pause. Even a short fast (24-48 hours) resulted in decreased androgen synthesis in women, while increasing aldosterone. In general, fasting...
    • haidut
    • Thread
    • aldosterone androgen caloric restriction cortisol estrogen fasting steroid
    • Replies: 1
    • Forum: Scientific Studies
  5. BlackMolasses

    People who eat very little but seem healthy?

    Usually the people I met who ate very little had obvious signs of hypothyroidism and poor health. But there is also a category of people who eat excessively little but seem very healthy. I have a friend in her 20s who needs to eat 1000 to 1500 calories a day, mostly from very low nutrient...
    • BlackMolasses
    • Thread
    • caloric restriction calories diet health nutrients nutrition
    • Replies: 2
    • Forum: Diet
  6. haidut

    Malnutrition (fasting) or protein deficiency sufficient to cause diabetes

    Yet another study that should give a pause to all health care providers who push their patients to lose weight at any cost - i.e. "lower is always better", when it comes to BMI, as the dogma goes. Well, apparently not, according to the study below. The even more astounding fact is that it looks...
    • haidut
    • Thread
    • bmi caloric restriction diabetes fasting malnutrition protein deficiency zinc
    • Replies: 3
    • Forum: Scientific Studies
  7. haidut

    Despite Striking Increase In Dieting And Exercise, Obesity Is Skyrocketing

    Maybe it takes a study like the one below to finally wake the public health authorities from their century-long slumber. I doubt there is a person alive today living in the Western world who has not been raised by the mantra "eat less and move more" as the single proven way to lose weight...
    • haidut
    • Thread
    • caloric restriction diet dieting exercise failure fasting obesity unsuccessful
    • Replies: 54
    • Forum: Scientific Studies
  8. haidut

    Low-protein High-carb Diet Has The Same Benefits As Caloric Restriction

    A recent study posted on the forum claimed that low carb is better for weight loss than other diets. Low Carb More Effective In Weight Loss Than High Carb? But the key question which so far most dieting studies ignore is this. Is the diet actually improving health and increasing lifespan...
    • haidut
    • Thread
    • benefit caloric restriction casein diet endotoxin fasting health high-carb lifespan longevity low-protein sucrose
    • Replies: 92
    • Forum: Scientific Studies
  9. haidut

    The Benefits Of Fasting Are Due To Lowering Endotoxin (LPS), Not Less Calories

    As many of you know, the argument for/against fasting has been raging on the forum for several years at this point. While Ray has spoken several times favorably about potentially skipping a meal or two, he has repeatedly said that chronic fasting is not something he recommends due to its...
    • haidut
    • Thread
    • antagonist benefits caloric restriction cr diabetes endotoxin fasting inflammation lps microbiome obesity tlr4
    • Replies: 39
    • Forum: Scientific Studies
  10. haidut

    Exercise + Fasting Is Stress, Causes Obesity And IR, And Requires Cortisol Blockade To Reverse

    I think this thread will ring true for all people who at some in their lives exercised in order to lose weight. Just like fasting, it works great in younger age (<30) but it really masks a bigger metabolic problem and of course badly backfired in the long run. Exercise is a forced/stressed...
    • haidut
    • Thread
    • antagonist caloric restriction corticol dhea exercise fasting glucocorticoid insulin resistance mifepristone obesity progesterone receptor ru486 stress
    • Replies: 148
    • Forum: Scientific Studies
  11. haidut

    Inhibiting Serotonin During Protein Feeding Doubles Maximum Lifespan

    This study is actually on the effects of a high protein diet on brain neurotransmitters and lifespan. It was done in fruit flies but the serotonin in those fruit flies are essentially the same in humans. So, the results should hold. One of the big takeaways from the study is the explanation of...
    • haidut
    • Thread
    • 5-ht2 caloric restriction doubles food inhibition lifespan perceived protein reward serotonin starvation tph
    • Replies: 14
    • Forum: Scientific Studies
  12. F

    Calorie Restriction In Peat Thinking [Life Extension]

    I just read this: http://www.economist.com/news/briefing/21704788-fight-cheat-death-hotting-up-adding-ages It explores life extension through calorie restriction. Peating seems to involve a lot more calories than normal Explanation?
  13. S

    Dietary Restriction Reduces Gut Pathology In Aging Females

    Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction Here are some clues about the real mechanisms behind the benefits.
  14. P

    Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-obese Youn

    http://www.ncbi.nlm.nih.gov/pubmed/26332798 Abstract Although caloric restriction (CR) could delay biologic aging in humans, it is unclear if this would occur at the cost of significant bone loss. We evaluated the effect of prolonged CR on bone metabolism and bone mineral density (BMD) in...
  15. P

    Effect Of Calorie Restriction And Refeeding On Skin Wound Healing In The Rat

    Effect of calorie restriction and refeeding on skin wound healing in the rat Abstract Calorie restriction (CR) is a reliable anti-aging intervention that attenuates the onset of a number of age-related diseases, reduces oxidative damage, and maintains function during aging. In the current...
  16. Giraffe

    Dietary Protein During Caloric Restriction

    A Systematic Review of Dietary Protein During Caloric Restriction in Resistance Trained Lean Athletes: A Case for Higher Intakes This review included only studies with adult lean athletes who performed resistance training during weight loss. " Training experience ranged from elite athletes and...
  17. NathanK

    For every 10% loss of body weight via underfeeding lowers metabolism 15%

    Interesting study. For every 10% of body weight lost due to underfeeding the subjects lowered their metabolism 15%. Changes in Energy Expenditure Resulting from Altered Body Weight Full text: http://www.nejm.org/doi/full/10.1056/NE ... #t=article "....Many obese people who lose weight have...
  18. haidut

    Low Protein / High Carb Diet - Healthier Than Caloric Restriction

    Ray has written about this before, several times across his many articles. He criticizes the caloric restriction (CR) studies due to the fact that the studies used toxic food ingredients, including PUFA. So, lowering those toxic food ingredients in the CR diets would produce a positive effect...
  19. haidut

    Low Calorie, Low Carb Intake Lowers T3 And Increases RT3

    Perfectly logical findings for those following Peat, but it is nonetheless nice to see even a mainstream "broscience" blog conclude that the only solution to curing the chronic low T3 syndrome is...to eat more and make sure a lot of the food is carbs. Also, it seems that people are also finally...
  20. haidut

    Optimal Diet For Increasing Lifespan

    Despite their many drawbacks due to being guided by wrong theories, some modern nutrition studies are starting to go in the right direction. This latest study looked at some important issues covered by both Peat and mainstream medicine. The issues are whether caloric restriction increases...
    • haidut
    • Thread
    • article caloric restriction diet hypocaloric lifespan study
    • Replies: 116
    • Forum: Scientific Studies
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