• tca300: I understand this is off topic from what you typically teach, but I was wondering if you have run across any information or learned on your own, things that help people grieve over lost loved ones, and or fear of losing others to death? Thank you!

    Ray Peat: It activates the “helplessness” reactions in the body, stress weakening your own life, and I think it can help to get out of that if you think of your life as a continuation of theirs—the same life, though with fewer bodies.

    Rest in Paradise, Raymond Peat  October 12, 1936 - November 24 2022

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calcitriol

  1. haidut

    Vitamin D3 anabolic, calcitriol catabolic for muscle/thymus

    Several great studies, which will probably do little to calm down the controversy that seems to be brewing lately in the blogosphere over whether supplementing with vitamin D3 is beneficial or not. Namely, the last study below demonstrated direct muscle-anabolic effects from supplementation with...
  2. haidut

    Vitamin D May Stop Melanoma Growth

    A great study that corroborates my recent post on avoiding sunlight being as bad for health as smoking a pack of cigarettes a day. After all, without sunlight there won't be much vitamin D synthesis and supplementation is not effective for many people due to variety of factors including excess...
  3. haidut

    High Estrogen (Androgen Deficiency) Causes Low Vitamin D; DHT Is Therapeutic

    I rarely stumble across studies like this one. Namely, showing in one single experiment both the detrimental effects of estrogen on one of the most important biomarkers of health (vitamin D), and the beneficial effects of a steroid long vilified/demonized by virtually everybody wearing a white...
  4. P

    Statins May Exert Beneficial Effects Through A Pathway Other Than It's Cholesterol Lowering Action

    Was surprised when saw a study showing statins have positive effects on bones, did a bit of searching and it turned out that it has some positive action,generally, through inhibiting rho kinase, which also is protective against heart disease. Im not promoting statin use at all(for obvious...
  5. ecstatichamster

    Calcium Speeds Up Prostate Cancer (but Fructose Slows It Down)

    An interesting study https://www.researchgate.net/profile/Alicja_Wolk/publication/13772836_Calcium_and_fructose_intake_in_relation_to_risk_of_prostate_cancer/links/02e7e526eb8b0d1f50000000.pdf Laboratory and clinical data indicate an antitumor effect of 1,25(OH)2 vitamin I) 11.25i()1h ,l)i on...
  6. haidut

    Vitamin D Restores Sensitivity To Cortisol

    The so-called "glucocorticoid resistance" is thought be behind a number of degenerative conditions including diabetes, depression, schizophrenia, chronic inflammation, autoimmune conditions, etc. The condition, similar to insulin resistance, is characterized by elevated serum cortisol levels and...
  7. haidut

    Vitamin D May Be Therapeutic Against Liver Fibrosis And Liver Cancer

    I posted a few threads on vitamin D and how it may help treat endotoxin-related condition, especially ones affecting the liver. Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked Conditions Endotoxin is perhaps the primary driver of actual liver fibrosis, which (if left...
  8. haidut

    Androgens (DHT, T) Treat Prostate Cancer, Especially When Combined With Vitamin D

    I recently posted a study showing that vitamin D inhibits the deactivation of androgens, which results in a build up of strong androgens like DHT. https://raypeatforum.com/community/threads/vitamin-d-inhibits-the-deactivation-of-androgens.12411/ That study conclude that this effect of vitamin D...
  9. haidut

    Vitamin D Inhibits The Deactivation Of Androgens

    Vitamin D is one of the most versatile substances in Peat world. It is actually a steroid and not a true vitamin, and as a steroid it is expected to have effects on other steroids. Its role in opposing estrogen, together with the other fat-soluble vitamins, is well-known. Now, this study shows...
  10. haidut

    Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked Conditions

    The activation of TLR by various substances like endotoxin, ethanol / alcohol, opioids, SSRI, etc is involved in the pathogenesis of many conditions, especially IBD, colon cancer, periodontal disease, etc. There are very few effective endotoxin antagonists in clinical use, which is unfortunate...
  11. haidut

    Vitamin D Is Dopaminergic And Decreases Obesity And Addiction Behaviors

    Over the last few years, I have posted studies on the forum showing that the vitamin E, A, and K all have dopaminergic activity that contributes to their positive effects on metabolism and health. This study discovered that vitamin D is another potent dopamine agonist, and that its dopaminergic...
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