caffeine

  1. Dan W

    Caffeine powder crackdown

    The FDA has recently sent warning letters to caffeine powder suppliers, causing them to discontinue many of their products. It's hard to tell whether the FDA's complaints can be addressed by introducing altered products/labeling, but I'm paranoid :tinfoilhat that this may be the end of...
    • Dan W
    • Thread
    • caffeine supplemental supplier
    • Replies: 28
    • Forum: Caffeine
  2. haidut

    Vitamin B3 Blocks FFA Elevation Caused By Caffeine

    Even though it is a logical finding knowing how niacinamide works, I still wanted to post this since it is one of the few studies looking at the combined effects of Peat substances like niacinamide and caffeine. I guess for simplicity you can assume that taking as much niacinamide as caffeine...
  3. haidut

    Caffeine Increases Both Gastric Acid And Pepsin Levels

    I know several people on the forum taking digestive enzymes and Peat also wrote that low gastric acid is one of the main signs (and issues) in hypothyroidism. So, before you go and spend money on pepsin capsules and digestive enzymes, you may want to try caffeine with your meals. The study...
  4. haidut

    Aspirin Is Dopaminergic; Additive Effects With Caffeine

    It is a well established fact that caffeine is dopaminergic in effect even though it does not bind directly to any dopamine "receptors". It looks like aspirin is also dopaminergic. As you can see from the study, using aspirin alone required doses equivalent do 5g - 6g in a human. However, in a...
  5. haidut

    Full Tolerance To Stress Response Of Caffeine Within 4 Days

    Event the people who find that caffeine gives them a "stress response" or raises their blood pressure, cortisol, etc should be able to quickly adapt. This study shows complete adaptation to all parameters of the "stress response" induced by 250mg caffeine daily. The adaptation occurred in as...
  6. haidut

    Caffeine And Aspirin Improve Both Mood And Performance

    Human study with low dose of caffeine and moderate dose of aspirin. http://www.ncbi.nlm.nih.gov/pubmed/3680601 "...We observed that caffeine (64 mg), when added to aspirin (800 mg), significantly improves vigilance performance and increases self-reported efficiency when compared with either...
  7. haidut

    Caffeine Increases Absorption And Concentration Of Aspirin

    Just a note for those using the two nutrients together. http://www.ncbi.nlm.nih.gov/pubmed/3720797 "...The effects of caffeine on the pharmacokinetics and bioavailability of aspirin were studied in 12 healthy adult male volunteers. The subjects received 650 mg of aspirin or 650 mg of aspirin...
  8. haidut

    Optimal Dose Of Caffeine In Humans

    Many people on the forum and elsewhere take caffeine for its pro-metabolic and disease-preventing effects. However, caffeine can induce a stress response. This is especially true in people with poor glycogen stores, liver problems, and hypothyroidism in general. This study says that a human dose...
  9. haidut

    Caffeine Lowers Serotonin Levels Raised By Exercise (stress)

    As many of you know, TPH is the enzyme responsible for synthesizing serotonin from tryptophan. Inhibiting TPH leads to rapid decreases of the levels of serotonin. There is TPH1 (expressed in the brain) and TPH2 (expressed in peripheral tissues). Inhibiting TPH1 has been shown to ameliorate...
  10. haidut

    Caffeine Lowers Parathyroid Hormone (PTH)

    The study tested both calcium and caffeine. Caffeine had a significant effect at a dose of about 300mg for a human. Calcium had a biphasic effect - lower dose of calcium increased PTH, while a higher dose lowered it. The high dose calcium was equivalent to a human dose of about 1,500mg - 2,000mg...
  11. haidut

    Caffeine - A "new" Drug For Depression / Social Defeat

    Caffeine has been popping up in the news lately. Several studies caught my eye, so I am posting them here. Two independent groups of researchers found out that caffeine protects against stress-induced mood and memory dysfunction. One of the studies focused on depression and found that increase...
  12. S

    Fasting Enhances Arousal Effect Of Caffeine In Mice.

    Fasting activated histaminergic neurons and enhanced arousal effect of caffeine in mice.
  13. B

    Microdosing Caffeine

    Over the past couple months I've tried to be able to consume coffee, but no matter what I did (tons of sugar and milk, with meals, taurine, etc.) it always ended with the same low blood sugar anxiety crash after the short lived feel good buzz. For the past two weeks I ditched caffeine completely...
  14. haidut

    Topical Caffeine For Weight Loss

    This study shows that adding caffeine to an herbal extract used for weight loss resulted in increasing its fat loss efficacy by more than 100%. The herbal extract was used topically as a 2% solution and caffeine was added in the same concentration as adjuvant. After 32 days there was significant...
  15. Dan W

    Coffee an hour after a meal was still effective at inhibiting iron absorption

    I think it was BigPapaChakra who found this: http://ajcn.nutrition.org/content/37/3/416.long The relevant part to coffee-timing is study 3:
  16. Dan W

    Coffee And Cocoa As Aromatase Inhibitors

    I had to post this because we've gone nearly 17 minutes without discussing an aromatase inhibitor :lol: I don't have access to the full text of this study, but it's referenced elsewhere as showing coffee and cocoa strongly inhibiting aromatase in a microsomal assay...
  17. Y

    Study Says Coffee/caffeine Shortens Lifespan By Shortening Telomeres

    Hi all, Please refer to the study below. It basically says that coffee, decreases telomeres which are end parts of DNA. Which increases cellular death chance. And telomeres are associated with poor health, and shorter lifespan. alcohol on other hand, increased it. NOT saying i believe this...
  18. J

    Caffeine Inhibits GABA

    I'm trying to understand the Peatish position on this. I know Peat is a huge fan of GABA, for instance: "The similarity between the structures and actions of glycine and GABA suggest that their “receptors” are similar, if not identical. For years, it has been known that progesterone and...
  19. S

    Circadian Autophagy, Fat Liver, Lithium And Caffeine

    Atg7 complementation resulted in reduced hepatic fatty acid infiltration ( Figures 6A and 6B), liver triglyceride content ( Figure 6C), and serum insulin level ( Figure 6D). There was a modest increase in serum triglyceride, but not free fatty acid levels, in mice expressing exogenous Atg7 (...
  20. haidut

    Caffeine Is A Potent Anti-estrogen; Can Block Estrogen "receptor" Completely

    After reading the study on caffeine and breast cancer I posted in a different thread, I found some facts that U thought warranted a separate thread. Here is the original thread. viewtopic.php?f=75&t=6481 It looks like caffeine has such a potent anti-estrogenic activity that it is capable of...
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